Patents by Inventor Crystal Marie Anderson-Cunanan
Crystal Marie Anderson-Cunanan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11304798Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.Type: GrantFiled: May 15, 2019Date of Patent: April 19, 2022Assignee: Boston Scientific Scimed, Inc.Inventors: David Robert Wulfman, Thomas A. Wrobel, Crystal Marie Anderson-Cunanan, Joseph Thomas Delaney, Jr., Patrick Willoughby, Mark W. Boden, Peter G. Edelman, Michael Eppihimer
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Patent number: 10443107Abstract: A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).Type: GrantFiled: July 25, 2018Date of Patent: October 15, 2019Assignee: Boston Scientific Scimed, Inc.Inventors: Crystal Marie Anderson-Cunanan, Daniel J. Foster, Ray McCarthy, Mary M. Byron, David Robert Wulfman, Bradley S. Swehla
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Patent number: 10405975Abstract: A prosthetic heart valve provided herein can include a cultured cell tissue leaflet. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member. The cultured cell tissue can be obtained by culturing fibroblast cells, smooth muscle cells, or a combination thereof to form a sheet of cultured cells and chemically cross-linking the fibroblast cells while under tension. In some cases, the cultured cell tissue can be radially tensioned. In some cases, the cultured cell tissue can be bi-axially tensioned.Type: GrantFiled: September 22, 2016Date of Patent: September 10, 2019Assignee: Boston Scientific Scimed, Inc.Inventors: Crystal Marie Anderson-Cunanan, Katherine Cora Fazackerley, Michael Eppihimer, Shannon Smith Kenwood, Natalia P. Sushkova, Karen Suzanne Lavery
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Publication number: 20190262131Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.Type: ApplicationFiled: May 15, 2019Publication date: August 29, 2019Inventors: David Robert Wulfman, Thomas A. Wrobel, Crystal Marie Anderson-Cunanan, Joseph Thomas Delaney, JR., Patrick Willoughby, Mark W. Boden, Peter G. Edelman, Michael Eppihimer
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Patent number: 10314696Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.Type: GrantFiled: March 28, 2016Date of Patent: June 11, 2019Assignee: Boston Scientific Scimed, Inc.Inventors: David Robert Wulfman, Thomas A. Wrobel, Crystal Marie Anderson-Cunanan, Joseph Thomas Delaney, Jr., Patrick Willoughby, Mark W. Boden, Peter G. Edelman, Michael Eppihimer
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Patent number: 10231830Abstract: A prosthetic heart valve provided herein can include a kidney capsule tissue leaflet. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member. The kidney capsule tissue can be obtained from a farm animal, such as a cow, pig, horse, goat, or sheep. In some cases, the kidney capsule tissue can be tensioned (e.g., bi-axially tensioned) and/or chemically cross-linked.Type: GrantFiled: November 1, 2016Date of Patent: March 19, 2019Assignee: Boston Scientific Scimed, Inc.Inventors: Lynne E. Swanson, Crystal Marie Anderson-Cunanan, Katherine Cora Fazackerley, Philip D. Crompton
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Patent number: 10195024Abstract: A prosthetic heart valve provided herein can include a porcine small intestine submucosa (P-SIS) tissue leaflet. The P-SIS tissue can include multiple stacked layers that are tensioned and cross-linked to form a material having a thickness of between 50 microns and 0.33 mm. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member.Type: GrantFiled: September 22, 2016Date of Patent: February 5, 2019Assignee: Boston Scientific Scimed, Inc.Inventors: Crystal Marie Anderson-Cunanan, Katherine Cora Fazackerley
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Publication number: 20180327871Abstract: A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).Type: ApplicationFiled: July 25, 2018Publication date: November 15, 2018Inventors: Crystal Marie Anderson-Cunanan, Daniel J. Foster, Ray McCarthy, Mary M. Byron, David Robert Wulfman, Bradley S. Swehla
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Patent number: 10080820Abstract: A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).Type: GrantFiled: August 29, 2016Date of Patent: September 25, 2018Assignee: Boston Scientific Scimed, Inc.Inventors: Crystal Marie Anderson-Cunanan, Daniel J. Foster, Ray McCarthy, Mary M. Byron, David Robert Wulfman, Bradley S. Swehla
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Publication number: 20170128201Abstract: A prosthetic heart valve provided herein can include a kidney capsule tissue leaflet. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member. The kidney capsule tissue can be obtained from a farm animal, such as a cow, pig, horse, goat, or sheep. In some cases, the kidney capsule tissue can be tensioned (e.g., bi-axially tensioned) and/or chemically cross-linked.Type: ApplicationFiled: November 1, 2016Publication date: May 11, 2017Inventors: Lynne E. Swanson, Crystal Marie Anderson-Cunanan, Katherine Cora Fazackerley, Philip D. Crompton
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Publication number: 20170100237Abstract: A prosthetic heart valve provided herein can include a cultured cell tissue leaflet. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member. The cultured cell tissue can be obtained by culturing fibroblast cells, smooth muscle cells, or a combination thereof to form a sheet of cultured cells and chemically cross-linking the fibroblast cells while under tension. In some cases, the cultured cell tissue can be radially tensioned. In some cases, the cultured cell tissue can be bi-axially tensioned.Type: ApplicationFiled: September 22, 2016Publication date: April 13, 2017Inventors: Crystal Marie Anderson-Cunanan, Katherine Cora Fazackerley, Michael Eppihimer, Shannon Smith Kenwood, Natalia P. Sushkova, Karen Suzanne Lavery
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Publication number: 20170100238Abstract: A prosthetic heart valve provided herein can include a porcine small intestine submucosa (P-SIS) tissue leaflet. The P-SIS tissue can include multiple stacked layers that are tensioned and cross-linked to form a material having a thickness of between 50 microns and 0.33 mm. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member.Type: ApplicationFiled: September 22, 2016Publication date: April 13, 2017Inventors: Crystal Marie Anderson-Cunanan, Katherine Cora Fazackerley
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Publication number: 20170065744Abstract: A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).Type: ApplicationFiled: August 29, 2016Publication date: March 9, 2017Inventors: Crystal Marie Anderson-Cunanan, Daniel J. Foster, Ray McCarthy, Mary M. Byron, David Robert Wulfman, Bradley S. Swehla
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Publication number: 20160296323Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.Type: ApplicationFiled: March 28, 2016Publication date: October 13, 2016Inventors: David Robert Wulfman, Thomas A. Wrobel, Crystal Marie Anderson-Cunanan, Joseph Thomas Delaney, JR., Patrick Willoughby, Mark W. Boden, Peter G. Edelman, Michael Eppihimer