Patents by Inventor Csaba FEKETE

Csaba FEKETE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic mouse for the assessment of thyroid hormone (TH) action
    Patent number: 10694724
    Abstract: A transgenic animal model that is suitable for the cell or tissue specific assessing of thyroid hormone (TH) action in vivo is described. The recombinant DNA construct and methods suitable to generate such an animal are also provided. The assessment of TH action is based on a reporter that is dependent on an endogenously expressed thyroid hormone receptor (TR) and coregulators of said receptor.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: June 30, 2020
    Assignee: Kisérleti Orvostudoányi Kutatóintézet
    Inventors: Csaba Fekete, Balázs Gereben, Petra Mohácsik, Ferenc Erdélyi, Gábor Szabó
  • TRANSGENIC MOUSE FOR THE ASSESSMENT OF THYROID HORMONE (TH) ACTION
    Publication number: 20170325429
    Abstract: A transgenic animal model that is suitable for the cell or tissue specific assessing of thyroid hormone (TH) action in vivo is described. The recombinant DNA construct and methods suitable to generate such an animal are also provided. The assessment of TH action is based on a reporter that is dependent on an endogenously expressed thyroid hormone receptor (TR) and coregulators of said receptor.
    Type: Application
    Filed: November 30, 2015
    Publication date: November 16, 2017
    Inventors: Csaba FEKETE, Balázs GEREBEN, Petra MOHÁCSIK, Ferenc ERDÉLYI, Gábor SZABÓ
  • PREIMPLANTATION ASSESSMENT OF EMBRYOS THROUGH DETECTION OF FREE EMBRYONIC DNA
    Publication number: 20170002414
    Abstract: The invention provides an in vitro method for non-invasive preimplantation assessment of an embryo by comprising amplifying and detecting a nucleic acid sequence of interest indicative of a genetic deficiency from a sample taken from the in vitro culture medium of the embryo and assessing the embryo as having a genetic deficiency if the presence of the sequence of interest is detected in the in vitro culture medium of the embryo. The examples show the detection of SNPs relating to the genes MDR1 and prothrombin and the SNP responsible for the Leiden syndrome. The application also mentions the possibility of establishing short tandem repeat (STR) marker profiles of DNA in the culture medium and full genome sequencing of the DNA in the culture medium as a means for determining embryo quality.
    Type: Application
    Filed: January 30, 2015
    Publication date: January 5, 2017
    Inventors: József BÓDIS, L. Gábor KOVÁCS, István VERMES, Csaba FEKETE, Orsolya RIDEG, Zoltán Endre BIHARI, Ferenc Péter PACH, Emese BATÓ, Ildikó PAPP, Bence GÁLIKK, Csaba SZERZÖ