Patents by Inventor Csaba Lorincz

Csaba Lorincz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4424223
    Abstract: The invention relates to the new 17,18-dehydro-apovincaminol-3',4',5'-trimethoxy-benzoate of formula (I) ##STR1## and acid addition salts thereof. According to another aspect of the invention there is provided a process for the preparation of these new compounds. Still another aspect of the invention is a pharmaceutical composition for treating psoriasis.
    Type: Grant
    Filed: February 4, 1982
    Date of Patent: January 3, 1984
    Assignee: Richter Gedeon Vegyeszeti Gyar RT
    Inventors: Tibor Keve, Bela Zsadon, Gyorgy Fekete, Csaba Lorincz, Janos Galambos, Maria Zajer nee Balazs, Lilla Forgach, Egon Karpati, Arpad Kiraly, Gyongyver Kiraly nee Soos, Laszlo Szporny, Bela Rosdy
  • Patent number: 4419359
    Abstract: The present invention relates to the compounds of the Formulae 1a and 1b and pharmaceutically acceptable acid addition salts thereof.The new 9-nitro-apovincaminol-3',4',5'-trimethoxybenzoate of the Formula 1a ##STR1## and the 11-nitro-apovincaminol-3',4',5'-trimethoxy-benzoate of the Formula 1b ##STR2## and pharmaceutically acceptable acid addition salts thereof can be prepared by nitrating the apovincaminol-3',4',5'-trimethoxy-benzoate of the Formula 11, ##STR3## if desired separating the mixture of the compounds of the Formulae 1a and 1b thus obtained into its components, if desired converting a compound of the Formula 1a or 1b thus obtained into pharmaceutically acceptable acid addition salts thereof.The new compounds of the present invention can be used in therapy in the treatment of psoriasis.
    Type: Grant
    Filed: February 4, 1982
    Date of Patent: December 6, 1983
    Assignee: Richter Gedeon Vegyeszeti Gyar RT
    Inventors: Tibor Keve, Gyorgy Fekete, Csaba Lorincz, Janos Galambos, Bela Zsadon, Maria Zajer nee Balazs, Lilla Forgach, Egon Karpati, Arpad Kiraly, Gyongyver Kiraly nee Soos, Laszlo Szporny, Bela Rosdy
  • Patent number: 4334910
    Abstract: A herbicidal composition capable of preventing weed growth of potatoes or soybean plants consists of a triazene or an aromatic nitro compound together with an inorganic salt, especially sodium bisulfate or potassium bisulfate which reduced the quantity of the organic herbicide below that usually required to obtain a corresponding herbicidal effect and hence prevents phytotoxic damage. The composition contains 0.1:1 to 15:1 parts by weight of the inorganic compound to the organic compound and is applied in an amount of 0.1 to 30 kg of the composition per hectare.
    Type: Grant
    Filed: August 30, 1976
    Date of Patent: June 15, 1982
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Csaba Lorincz, Eva Lorincz nee Csapo, Istvan Gebhardt, Antal Gimesi, Bela Stefko, Erik Bogsch, Zsuzsanna Foldesi nee Szasz, Kalman Szasz
  • Patent number: 4209443
    Abstract: A mixture of minor diindole alkaloids from Vinca-containing vinblastine and 4-deacetoxy-vinblastine vines, are separated by subjecting the mixture to a deacetylation to correct the vinblastine to deacetyl-vinblastine prior to chromatographic separation of said mixture in a single stage.
    Type: Grant
    Filed: March 1, 1978
    Date of Patent: June 24, 1980
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Karola Jovanovics, Lajos Dancsi, Sandor Eckhardt, Csaba Lorincz, Janos Sugar, Zsuzsa Relle nee Somfai, Kalman Szasz, Jozsef Tamas, Aron Szollosy
  • Patent number: 4199505
    Abstract: A process for the preparation of alkaloids of the leurosine type having the formula I ##STR1## and the acid addition salts thereof. In the formula I R is hydrogen or methyl. The compounds prepared according to the invention are known compounds showing cytostatic activity.
    Type: Grant
    Filed: May 19, 1978
    Date of Patent: April 22, 1980
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Csaba Szantay, Lajos Szabo, Katalin Honty, Katalin Nogradi, Karola Jovanovics, Eszter Dezseri, Lajos Dancsi, Csaba Lorincz, Bela Szarvady, Lajos Kovacs
  • Patent number: 4172077
    Abstract: Tumor inhibiting alkaloids are recovered from Vinca Rosea L. by a method which comprises extracting the dried leaves with a solvent selected from the group consisting of an alkanol having 1 to 5 carbon atoms, a mixture of an alkanol having 1 to 5 carbon atoms and a dilute, aqueous solution, benzene and benzene homologs; subsequently purifying the alkaloid extract obtained by a phase-change method between immiscible solvents, precipitating the main amount of dimeric alkaloids in form of their sulphuric acid addition salts, isolating leurosine, vincistine, vinblastine, desacetoxy-vinblastine, N-desmethyl-vinblastine and desacetyl-vinblastine from the salt mixture obtained, and then completing the separation and isolation of the remaining alkaloids by separation and isolation by adjusting the pH-value of the mother liquor, after precipitation and removal of the salt mixture, to 5.
    Type: Grant
    Filed: May 22, 1978
    Date of Patent: October 23, 1979
    Assignee: Richter Gedeon Vegyeszeti Gyar RT
    Inventors: Karola Jovanovics, Gyorgy Fekete, Eszter Dezseri, Lajos Dancsi, Csaba Lorincz, Bela Szarvady, Gyorgy Dobo, Csaba Szantay, Lajos Szabo
  • Patent number: 4108996
    Abstract: Apovincaminol ester of formula ##STR1## wherein R is an alkylcarbonyl group having 3 to 12 carbon atoms, or a pharmaceutically acceptable acid addition salt thereof.
    Type: Grant
    Filed: July 7, 1976
    Date of Patent: August 22, 1978
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Csaba Lorincz, Maria Bolyos, Kalman Szasz, Laszlo Szporny, Egon Karpati, Eva Palosi
  • Patent number: 4070358
    Abstract: A process is disclosed for the separation and recovery of vinblastine and leurosine from a mixture of diindole alkaloids obtained by extraction of the plant, Vinca rosea L.
    Type: Grant
    Filed: October 22, 1976
    Date of Patent: January 24, 1978
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt
    Inventors: Karola Jovanovics, Kalman Szasz, Csaba Lorincz, Laszlo Hermann, Eszter Dezseri
  • Patent number: 4065458
    Abstract: A heart and vasotropic pharmaceutical of the formula: ##STR1## wherein R represents a hydrogen atom or an acyl group, preferably a C.sub.1-15 alkylcarbonyl, C.sub.2-6 alkenylcarbonyl, or a phenyl- (C.sub.1-5)-alkylcarbonyl group or a benzoyl group optionally substituted with halogen, trihalomethyl, C.sub.1-4 or nitroAnd pharmaceutically acceptable acid addition and quaternary salts thereof.
    Type: Grant
    Filed: June 9, 1976
    Date of Patent: December 27, 1977
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Csaba Lorincz, Kalman Szasz, Maria Bolyos, Karola Jovanovics, Laszlo Szporny, Egon Karpati, Eva Palosi
  • Patent number: 4035370
    Abstract: Vasodilatory eburnamine-type alkaloid esters of the formula (I) ##STR1## and salts and quaternary derivatives thereof, wherein X.about.Y REPRESENTS A =CH=CH- or ##STR2## R represents a C.sub.1-6 alkoxycarbonyl group optionally substituted with a hydroxy group or with a halogen atom, further an alkenyloxycarbonyl, aryloxycarbonyl, aralkoxycarbonyl group or an acylated primary alcohol group, especially apovincaninic acid ethyl ester, have been prepared by various methods of esterification.
    Type: Grant
    Filed: December 29, 1975
    Date of Patent: July 12, 1977
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Csaba Lorincz, Egon Karpati, Laszlo Szporny, Kalman Szasz, Lajos Kisfaludy