Patents by Inventor Csaba Varadi

Csaba Varadi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220163549
    Abstract: The present teachings relate to methods, systems, and kits for the preparation, purification and/or analysis of a glycan or glycoconjugate, and specifically to a magnetic bead based sample preparation protocol. In some aspects, the sample preparation protocol can provide for glycoconjugate capture, glycan release, fluorescent derivatization, and glycan purification for subsequent capillary electrophoresis, liquid chromatography, or other glycoanalytical method using magnetic beads containing negatively charged carboxyl groups extending from the surface of the magnetic beads.
    Type: Application
    Filed: February 14, 2022
    Publication date: May 26, 2022
    Inventors: Andras Guttman, Clarence Lew, Marton Szigeti, Csaba Varadi
  • Patent number: 11249098
    Abstract: The present teachings relate to methods, systems, and kits for the preparation, purification and/or analysis of a glycan or glycoconjugate, and specifically to a magnetic bead based sample preparation protocol. In some aspects, the sample preparation protocol can provide for glycoconjugate capture, glycan release, fluorescent derivatization, and glycan purification for subsequent capillary electrophoresis, liquid chromatography, or other glycoanalytical method using magnetic beads containing negatively charged carboxyl groups extending from the surface of the magnetic beads.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: February 15, 2022
    Assignee: Beckman Coulter, Inc.
    Inventors: Andras Guttman, Clarence Lew, Marton Szigeti, Csaba Varadi
  • Publication number: 20210147329
    Abstract: The present invention relates to a process for the preparation of iloprost of formula I through new intermediates, isolation of iloprost of formula I in solid form, as well as preparation of the 16(S)-iloprost and 16(R)-iloprost isomers of formulae (S)-I and (R)-I and isolation of iloprost of formula I and 16(S)-iloprost of formula (S)-I in solid, crystalline form.
    Type: Application
    Filed: April 16, 2019
    Publication date: May 20, 2021
    Applicant: CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA ZRT.
    Inventors: Imre ROZSUMBERSZKI, Zsuzsanna KARDOS, Irén HORTOBÁGYI, Tibor SZABÓ, Csaba VÁRADI, Tamás BÁN
  • Patent number: 10442762
    Abstract: The subject of the invention is a novel process for the preparation of Carboprost tromethamine salt where alkylation the enone of the general formula (II) is carried out in the presence of a chiral auxiliary in aprotic solvent with a Grignard reagent. The methyl ester epimers of formula (VII) are separated by gravity silica gel chromatography and the salt formation is carried out by using solid tromethamine base.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: October 15, 2019
    Assignee: CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA ZRT.
    Inventors: Péter Buzder-Lantos, Zsuzsanna Kardos, Irén Hortobágyi, István Lászlófi, Imre Juhász, László Fónagy, Csaba Váradi, Ágnes Nagyné Borkó
  • Publication number: 20190227086
    Abstract: The present teachings relate to methods, systems, and kits for the preparation, purification and/or analysis of a glycan or glycoconjugate, and specifically to a magnetic bead based sample preparation protocol that can enable full automation and reduced sample preparation time relative to current methods of glycoanalysis. In some aspects, the sample preparation protocol can provide for glycoconjugate capture, glycan release, fluorescent derivatization, and glycan purification for subsequent capillary electrophoresis, liquid chromatography, or other glycoanalytical method without requiring time-consuming sample preparation steps such as centrifugation or vacuum-centrifugation.
    Type: Application
    Filed: February 15, 2019
    Publication date: July 25, 2019
    Inventors: Andras Guttman, Clarence Lew, Marton Szigeti, Csaba Varadi
  • Patent number: 10247745
    Abstract: The present teachings relate to methods, systems, and kits for the preparation, purification and/or analysis of a glycan or glycoconjugate, and specifically to a magnetic bead based sample preparation protocol that can enable full automation and reduced sample preparation time relative to current methods of glycoanalysis. In some aspects, the sample preparation protocol can provide for glycoconjugate capture, glycan release, fluorescent derivatization, and glycan purification for subsequent capillary electrophoresis, liquid chromatography, or other glycoanalytical method without requiring time-consuming sample preparation steps such as centrifugation or vacuum-centrifugation.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: April 2, 2019
    Assignee: Beckman Coulter, Inc.
    Inventors: Andras Guttman, Clarence Lew, Marton Szigeti, Csaba Varadi
  • Publication number: 20180362457
    Abstract: The subject of the invention is a novel process for the preparation of Carboprost tromethamine salt where alkylation the enone of the general formula (II) is carried out in the presence of a chiral auxiliary in aprotic solvent with a Grignard reagent. The methyl ester epimers of formula (VII) are separated by gravity silicagel chromatography and the salt formation is carried out by using solid tromethamine base.
    Type: Application
    Filed: November 10, 2016
    Publication date: December 20, 2018
    Applicant: CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA ZRT .
    Inventors: Péter BUZDER-LANTOS, Zsuzsanna KARDOS, Irén HORTOBÁGYI, István LÁSZLÓFI, Imre JUHÁSZ, László FÓNAGY, Csaba VÁRADI, Ágnes NAGYNÉ BORKÓ
  • Publication number: 20170045538
    Abstract: The present teachings relate to methods, systems, and kits for the preparation, purification and/or analysis of a glycan or glycoconjugate, and specifically to a magnetic bead based sample preparation protocol that can enable full automation and reduced sample preparation time relative to current methods of glycoanalysis. In some aspects, the sample preparation protocol can provide for glycoconjugate capture, glycan release, fluorescent derivatization, and glycan purification for subsequent capillary electrophoresis, liquid chromatography, or other glycoanalytical method without requiring time-consuming sample preparation steps such as centrifugation or vacuum-centrifugation.
    Type: Application
    Filed: April 27, 2015
    Publication date: February 16, 2017
    Inventors: Andras Guttman, Clarence Lew, Marton Szigeti, Csaba Varadi