Patents by Inventor Cuicui YANG

Cuicui YANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Flavanone derivatives, and preparation method and use thereof
    Patent number: 10513512
    Abstract: The invention relates to flavanone derivatives, and preparation method and use thereof, particularly relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same, a preparation method thereof, and use thereof for preventing or treating a mental disorder or a nervous system disease. The compound of the invention exerts significant activity of inhibiting microglial activation and neuroinflammation, can antagonize dopamine D2 receptor, improve the ethological change in multiple animal models for mental disorders, effectively inhibit neuroinflammation and demyelination, and can be used to prevent or treat a mental disorder and a nervous system disease.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: December 24, 2019
    Assignee: Xuanwu Hospital of Capital Medical University
    Inventors: Lin Li, Hongshun Gu, Lan Zhang, Xi Chen, Linlin Yin, Ruyi Zhang, Cuicui Yang
  • FLAVANONE DERIVATIVES, AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20190031644
    Abstract: The invention relates to flavanone derivatives, and preparation method and use thereof, particularly relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same, a preparation method thereof, and use thereof for preventing or treating a mental disorder or a nervous system disease. The compound of the invention exerts significant activity of inhibiting microglial activation and neuroinflammation, can antagonize dopamine D2 receptor, improve the ethological change in multiple animal models for mental disorders, effectively inhibit neuroinflammation and demyelination, and can be used to prevent or treat a mental disorder and a nervous system disease.
    Type: Application
    Filed: January 11, 2017
    Publication date: January 31, 2019
    Applicant: Xuanwu Hospital of Capital Medical University
    Inventors: Lin LI, Hongshun GU, Lan ZHANG, Xi CHEN, Linlin YIN, Ruyi ZHANG, Cuicui YANG