Patents by Inventor Cuiling Zhao

Cuiling Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination of PVY monoclonal antibodies capable of recognizing different antigenic determinants, and use thereof
    Patent number: 12145979
    Abstract: The invention discloses a combination of PVY monoclonal antibodies capable of recognizing different antigenic determinants, and a use thereof, and belongs to the biotechnological field. Monoclonal antibodies N1, M1, M2, M3 and C1 obtained in the invention have specific CDRs, and are significantly different from existing reported monoclonal antibodies. The five monoclonal antibodies and a combination thereof can recognize all or most PVY isolates which have been reported, thus reducing the possibility of detection omissions; and the five monoclonal antibodies do not react with other congeneric viruses and non-congeneric viruses, thus reducing the possibility of detection errors. Therefore, the monoclonal antibodies and the combination thereof can realize accurate PVY detection.
    Type: Grant
    Filed: October 26, 2023
    Date of Patent: November 19, 2024
    Assignee: SHANDONG AGRICULTURAL UNIVERSITY
    Inventors: Xiangdong Li, Zhiyong Yan, Cuiling Zhao, Qing Zhu, Xiuqi Mu, Yanping Tian, Chao Geng
  • COMBINATION OF PVY MONOCLONAL ANTIBODIES CAPABLE OF RECOGNIZING DIFFERENT ANTIGENIC DETERMINANTS, AND USE THEREOF
    Publication number: 20240239872
    Abstract: The invention discloses a combination of PVY monoclonal antibodies capable of recognizing different antigenic determinants, and a use thereof, and belongs to the biotechnological field. Monoclonal antibodies N1, M1, M2, M3 and C1 obtained in the invention have specific CDRs, and are significantly different from existing reported monoclonal antibodies. The five monoclonal antibodies and a combination thereof can recognize all or most PVY isolates which have been reported, thus reducing the possibility of detection omissions; and the five monoclonal antibodies do not react with other congeneric viruses and non-congeneric viruses, thus reducing the possibility of detection errors. Therefore, the monoclonal antibodies and the combination thereof can realize accurate PVY detection.
    Type: Application
    Filed: October 26, 2023
    Publication date: July 18, 2024
    Inventors: Xiangdong LI, Zhiyong Yan, Cuiling Zhao, Qing Zhu, Xiuqi Mu, Yanping Tian, Chao Geng