Patents by Inventor Cuiwei Ai

Cuiwei Ai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LAG3 ANTAGONIST CELL BASED POTENCY ASSAY
    Publication number: 20230333090
    Abstract: The present disclosure describes a murine T cell 3A9 comprising a polynucleotide sequence encoding human LAG3, and a murine IL-2 promotor operably associated with a reporter gene. The disclosure also describes a cell-based potency assay for measuring LAG3 antagonist activity using a co-cultured system with the murine T cells and LK35.2 murine B cells, and hen egg lysozyme peptide.
    Type: Application
    Filed: December 16, 2020
    Publication date: October 19, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Kevin B. Gurney, Yue Zhang, Linda Liang, Cuiwei Ai