Patents by Inventor Cullen Schmid

Cullen Schmid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of 20-nor-salvinorin A
    Patent number: 11512075
    Abstract: The invention provides 20-nor-salvinorin A, an analog of the kappa-opioid agonist salvinorin A. The 20-nor-salvinorin A is an active kappa-opioid modulator and can be used for treatment of medical conditions wherein modulation of the kappa-opioid receptor is medically indicated, such as pain, pruritis, depression, or inflammation, or conditions implicating perception and consciousness. 20-nor-salvinorin A can be less additive when used in treatment compared to a mu-opioid receptor agonist, and 20-nor-salvinorin A is more stable in vivo than is parent compound salvinorin A. The invention further provides synthetic intermediates and procedures for preparation of 20-nor-salvinorin A.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: November 29, 2022
    Assignee: The Scripps Research Institute
    Inventors: Ryan Shenvi, Jeremy Roach, Yusuke Sasano, Laura Bohn, Cullen Schmid
  • SYNTHESIS OF 20-NOR-SALVINORIN A
    Publication number: 20200131162
    Abstract: The invention provides 20-nor-salvinorin A, an analog of the kappa-opioid agonist salvinorin A. The 20-nor-salvinorin A is an active kappa-opioid modulator and can be used for treatment of medical conditions wherein modulation of the kappa-opioid receptor is medically indicated, such as pain, pruritis, depression, or inflammation, or conditions implicating perception and consciousness. 20-nor-salvinorin A can be less additive when used in treatment compared to a mu-opioid receptor agonist, and 20-nor-salvinorin A is more stable in vivo than is parent compound salvinorin A. The invention further provides synthetic intermediates and procedures for preparation of 20-nor-salvinorin A.
    Type: Application
    Filed: June 7, 2018
    Publication date: April 30, 2020
    Inventors: Ryan Shenvi, Jeremy Roach, Yusuke Sasano, Laura Bohn, Cullen Schmid