Abstract: A system, includes a first screw mechanism including: a first block; a first screw threaded through the first block and including a first skin-interfacing portion; and an intramedullary (IM) member extending from and attached to the first block and including an end portion configured to be inserted into an intramedullary canal of a first bone fragment, wherein a first lateral force is generated between the first skin-interfacing portion against a second bone fragment, adjacent to the first bone fragment, and a holding force provided by the end portion when the first screw is rotated and the end portion is located in the intramedullary canal.

Abstract: A dental implant includes a generally cylindrical body, an interior bore, and a non-rotational feature. The generally cylindrical body has a main-central axis and is formed from cold-worked, high strength, commercially pure titanium having an ultimate tensile strength of at least about 900 MPa. The generally cylindrical body has a proximal portion and an opposing distal portion for anchoring the dental implant in bone of a patient. The interior bore is formed in the generally cylindrical body and has (i) a bore-central axis and (ii) a threaded portion for receiving a screw that is configured to removable hold an abutment in engagement with the dental implant. The non-rotational feature is configured to engage the abutment in a non-rotational fashion.

Abstract: Methods of designing, generating, screening, and identifying one or more of these peptides possessing multiple functionalities, for example, including (i) high binding to a cellular target (e.g., melanin pigment in the eye), (ii) high cell-penetration (e.g., to enter cells and access melanin in the melanosomes), and (ii) low cytotoxicity have been developed. Peptides or drug conjugates thereof having these multiple functionalities are particularly effective for selective delivery, prolonged residence, and sustained release of active agents to the epithelial tissues via mucosal surfaces. Methods of using these peptides are also described.

Abstract: A garment support includes a body including a top portion, a middle portion, and bottom portion, the top portion includes a first leg and a second leg defining a receptacle extending along a length of the body to receive and support a garment, and the bottom portion includes a lower edge that is pointed along the length of the body.

Abstract: A door structure system for a vehicle includes an inner panel, an outer panel, and an outer belt reinforcement member. The outer belt reinforcement member extends in a fore-and-aft direction of the door structure. The outer belt reinforcement member creates an overlap joint with a hem flange portion of the inner panel. The outer belt reinforcement member includes touch-down feature that extends toward the inner panel and into contact with a bearing surface of the inner panel that is stepped down relative to the hem flange portion. The overlap joint and the touch-down feature both contribute to an increased upper frame stiffness of the door structure and improve sealing performance between the door structure and the vehicle body structure.

Abstract: Provided are a system, method, and device for automatically synchronizing test information of a test for testing a software of an embedded system. According to embodiments, the method may be implemented by at least one processor and may include: collecting at least one test result of the testing; determining at least one test case associated with the at least one test result; determining, from among a plurality of test requirements of the at least one test case, at least one test requirement associated with the at least one test result; and synchronizing the at least one test result with the at least one test requirement.

Abstract: Provided are a system, method, and device for managing a test for testing software of an embedded system. According to embodiments, the method may be implemented by at least one processor and may include: receiving, from a user, at least one first user input associated with one or more test requirements; generating, based on the first user input, at least one test package; generating, based on the at least one test package, at least one test environment configuration file; validating the at least one test package and the at least one test environment configuration file; determining a change in the software; and based on determining the change in the software, executing the test according to the validated at least one test package and the validated at least one test environment configuration file, wherein the software of the embedded system may include an in-vehicle electronic control unit (ECU).

Abstract: An apparatus for a battery-powered active exoskeleton boot includes a shin pad and one or more housings. The one or more housings enclose electronic circuitry and an electric motor. The apparatus includes a battery holder coupled to the shin pad and located below the knee of the user and above the one or more housings enclosing the electronic circuitry. The apparatus includes a battery module removably affixed to the battery holder and comprising a first power connector that electrically couples to a second power connector located in the battery holder while attached to the battery holder to provide electric power to the electronic circuitry and the electric motor. The apparatus includes an output shaft coupled to the electric motor. The electronic circuitry controls delivery of power from the battery module to the electric motor to generate torque about the axis of rotation of the ankle joint of the user.

Abstract: The present technology provides for the learning of information relevant to a user account by a generative response engine and accessing this information when preparing personalized responses to prompts provided by the user account. A further aspect of the present technology is that the user account does not need to explicitly tell the generative response engine to remember a particular information. Instead, the present technology is configured such that the generative response engine can learn such facts, preferences, or contexts from conversational prompts provided to the chatbot without providing explicit instructions to remember the data. A further aspect of the present technology is that the user account can request that the generative response engine forget some learned facts too.

Abstract: An apparatus for an active exoskeleton boot is provided. The apparatus can include a foot plate disposed within a boot of a user. The apparatus can include a first adapter extending from a side surface of the foot plate having a slot and an actuator module comprising a chassis and a post, and the post coupled to the chassis. The apparatus can include a second adapter extending from an end surface of the post. The slot of the first adapter can be configured to engage the second adapter when the actuator module is positioned at a first angle relative to the first adapter. The first adapter can be configured to lock with the second adapter when the actuator module rotates from the first angle to a second angle relative to the first adapter.

Abstract: Disclosed herein are monoclonal antibodies that specifically bind to human mature Factor D and that do not bind to human Pro-Factor D, monoclonal antibodies that specifically bind to human Pro-Factor D and do not bind to human mature Factor D, and monoclonal antibodies that bind to both human mature Factor D and human Pro-Factor D. Also disclosed are methods of using the monoclonal antibodies, and compositions comprising the same, for detection of the mature and/or the pro-form of Factor D in biological samples, to determine the status of the Alternative Pathway of Complement (APC) in a mammalian subject, or to determine the status of Factor D after treatment with a MASP-3 inhibitory agent which inhibits the conversion of Pro-Factor D to mature Factor D.

Abstract: In its many embodiments, the invention provides compounds of structural Formula (I): (I), and pharmaceutically acceptable salts thereof, wherein, ring A, R1, R2 and R3 are as defined herein, and pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other therapeutically active agents). The invention further provides methods for the preparation and use of the compounds of the invention, or a pharmaceutically acceptable salt thereof, alone and in combination with other therapeutic agents, as antagonists of A2a and/or A2b receptors, and in the treatment of a variety of diseases, conditions, or disorders that are mediated, at least in part, by the adenosine A2a receptor and/or the adenosine A2b receptor.

Abstract: A system for generating electricity from a body of water that comprises an enclosure having a first upper aperture, a second upper aperture, and a closable lower outlet. The system furthers comprises a buoyant container movable within the enclosure between an upper position and a lower position. The container has an upper end that is at least partially open and a lower end having a closable drain. The system further comprises a set of upper supports coupled to the enclosure and configured to support the container in the upper position, and a set of lower supports fixed to the lower end of the enclosure to allow water to partially surround the buoyant container and help it float up to the upper position. The system comprises a cable, rod, or other connection member coupled at one end to the container and configured to extend through the enclosure for connection to an electrical generator.

Abstract: Collaborative computing and electronic records are disclosed. An entity that may be able to help achieve an objective is discovered and a connection to the entity established. A meta-language is used to exchange with the entity a description of the objective and a description of the entity. The meta-language is used to negotiate with the entity a contract to help achieve the objective. In the event a contract to help achieve the objective is reached, performing a self-configuration in accordance with the contract.

Abstract: Methods, apparatuses, and computer-readable media for providing a pedestrian-oriented navigation app for a mobile device. Destination information is received from a pedestrian using a mobile device. The mobile device retrieves pedestrian-oriented mapping data and routing for the navigation of the pedestrian to the destination, determines a current location and direction of the pedestrian based upon GPS data and compass data retrieved from the device, and displays the current location and direction of the pedestrian along with a route for the pedestrian to the destination on the user interface of the mobile device based on the pedestrian-oriented mapping data and routing. If the mobile device detects that the pedestrian has deviated from the route, the mobile device alters the display on the user interface to alert the pedestrian to the deviation.

Abstract: A recliner chair includes a mounting bracket configured to mount to a base. A seat portion and a back portion are attached at a frame that is pivotally attached at the mounting bracket. The frame is pivotable relative to the mounting bracket to move the seat portion and the back portion between a non-reclined position and a reclined position. An ottoman is pivotable relative to the base between a lowered position and a raised position. An actuator is operable to pivot the ottoman between the lowered position and the raised position and to pivot the frame to move the seat portion and the back portion between the non-reclined position and the reclined position. The actuator is disposed within a structure at a side of the recliner chair and outboard of the seat portion.