Patents by Inventor Curt Frils Nielsen

Curt Frils Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060252156
    Abstract: The present invention relates to methods of mixing large numbers of heterologous genes, which are located on artificial chromsomes. The methods of the present invention are useful for evolution of cells and whole genomes to acquire new functionality(ies), such as the ability to synthesise novel secondary metabolites and/or the evolution of novel metabolic pathways. In particular the methods may involve mating or fusing two populations of cells, each population comprising different combinations of heterologous genes. Subsequently, desirable cells may be selected. In embodiments of the invention the heterologous genes are comprised within expression cassettes. The expression cassette can be in the form of a concatermer, and can be cut out using a restriction enzyme in order to make new combinations of expression cassettes.
    Type: Application
    Filed: August 1, 2003
    Publication date: November 9, 2006
    Applicant: Evolva Ltd. c/o Dr. iur. Martin Eisenring
    Inventors: Neil Goldsmith, Soren Nielsen, Alexandra Sorensen, Curt Frils Nielsen