Abstract: Systems and methods for software development in which the development of a base product proceeds concurrently with the internationalization and localization of the base product to produce multiple language versions of the product for polylingual simultaneous shipment to customers wherein one or more of the multiple languages can be uploaded by the customer in a single installation process.

Abstract: High-intensity, spiked noise is reduced in chromatography-mass spectrometry data by applying a nonlinear filter such as a moving median filter to the data. The filter is applied to individual mass chromatograms, plots of ion abundance versus retention time for each detected mass-to-charge ratio, and the filtered chromatograms are combined to form a filtered total ion current chromatogram. Standard linear filters are not effective for reducing noise in liquid chromatography-mass spectrometry (LC-MS) data because they assume a normal distribution of noise. LC-MS noise, however, is not normally distributed.