Abstract: Disclosed are compositions comprising an antibody conjugated to one or more molecular guidance system (MGS) peptides. Disclosed are methods of treating a subject in need thereof comprising administering to the subject in need thereof an effective amount of an antibody conjugated to one or more MGS peptides, wherein the antibody targets an intracellular target involved in the disease process. Disclosed are methods of targeting an intracellular target comprising administering an antibody conjugated to one or more MGS peptides, wherein the antibody targets an intracellular target.

Abstract: Disclosed herein, are compositions comprising one or more a molecular guidance system (MGS) peptides and a cytotoxic agent. Also described herein, are methods of administering the compositions to patients with cancer.

Abstract: Disclosed herein, are compositions comprising one or more molecular guidance system (MGS) peptides and a cytotoxic agent. Also described herein, are methods of administering the compositions to patients with cancer.

Abstract: Disclosed are compositions comprising a nucleic acid sequence conjugated to one or more MGS peptides. Disclosed are methods of modifying gene expression of a gene of interest comprising administering to a cell a composition comprising a nucleic acid sequence conjugated to one or more MGS peptides, wherein the nucleic acid sequence binds to the RNA transcribed from the gene of interest, the gene of interest or a sequence upstream of the gene of interest. Disclosed are methods of targeting a gene of interest in an intracellular target comprising administering to a cell a composition comprising a nucleic acid sequence conjugated to one or more MGS peptides, wherein the MGS peptide targets the intracellular target, wherein the nucleic acid sequence binds to the RNA transcribed from the gene interest in an intracellular target.

Abstract: Disclosed herein, are compositions comprising one or more molecular guidance system (MGS) peptides and a cytotoxic agent. Also described herein, are methods of administering the compositions to patients with cancer.

Abstract: Disclosed are compositions comprising an antibody conjugated to one or more molecular guidance system (MGS) peptides. Disclosed are methods of treating a subject in need thereof comprising administering to the subject in need thereof an effective amount of an antibody conjugated to one or more MGS peptides, wherein the antibody targets an intracellular target involved in the disease process. Disclosed are methods of targeting an intracellular target comprising administering an antibody conjugated to one or more MGS peptides, wherein the antibody targets an intracellular target.

Abstract: A computer system processes a message from a user mobile device by receiving the message from the user mobile device, wherein the message comprises a purchase request, and then determining a matching purchase offer in a database containing a plurality of purchase offers, wherein the matching purchase offer corresponds to an offer identified in the purchase request. The system then transmits a purchase request to a purchase agent at a third party provider that is associated with the matching purchase offer, and processing a purchase transaction received from the purchase agent at the third party provider.

Abstract: A distributed computational system, with local and remote processing components, is configured to provide a user interface of the local component that is stored in the local component but is controlled and updated by the remote component.

Abstract: A computer system processes a message from a user mobile device by receiving the message from the user mobile device, wherein the message comprises a purchase request, and then determining a matching purchase offer in a database containing a plurality of purchase offers, wherein the matching purchase offer corresponds to an offer identified in the purchase request. The system then transmits a purchase request to a purchase agent at a third party provider that is associated with the matching purchase offer, and processing a purchase transaction received from the purchase agent at the third party provider.

Abstract: A network comprising a server and a remote client including an input output pin is disclosed. The server and the client are connected through a Transmission Control Protocol (TCP) connection. The server controls the client input output pin, e.g., switches it on and off. The input output pin control instruction is transmitted from the server to the client. The control instruction is not stored in the client memory upon its execution.

Abstract: A single integrated circuit chip interfaces device control circuitry of a device to a client machine via a computer network. The chip comprises an internal data bus; a central processing unit connected to the internal data bus; an internal memory connected to the internal data bus; a device interface connected to the internal data bus, wherein the device interface comprises circuit blocks for communicating digital information between the integrated circuit and the device control circuitry; and a network interface connected to the internal data bus, wherein the network interface comprises circuit blocks for communicating digital information between the integrated circuit and the computer network.