Patents by Inventor Curtis Cetrulo

Curtis Cetrulo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240139242
    Abstract: The technology described herein is directed to compositions comprising components of multi-component CALs or CARs, e.g., a TCR recognition domain; and one or both of: (a) an intracellular signaling domain; and (b) a first-type protein interaction domain. Further provided herein are methods for treating or preventing an autoimmune disease, a transplant rejection, or graft versus host disease.
    Type: Application
    Filed: October 16, 2020
    Publication date: May 2, 2024
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, THE GENERAL HOSPITAL CORPORATION
    Inventors: Mohammadreza PAKYARI, Wilson WONG, Atsushi OKUMA, Curtis CETRULO
  • Publication number: 20230321183
    Abstract: The technology described herein is directed to compositions comprising components of multi-component CALs or CARs, e.g., a TCR recognition domain; and one or both of: (a) an intracellular signaling domain; and (b) a first-type protein interaction domain. Further provided herein are methods for treating or preventing an autoimmune disease, a transplant rejection, or graft versus host disease.
    Type: Application
    Filed: June 16, 2023
    Publication date: October 12, 2023
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, THE GENERAL HOSPITAL CORPORATION
    Inventors: Mohammadreza PAKYARI, Wilson WONG, Atsushi OKUMA, Curtis CETRULO
  • Patent number: 11723950
    Abstract: The technology described herein is directed to compositions comprising components of multi-component CALs or CARs, e.g., a TCR recognition domain; and one or both of: (a) an intracellular signaling domain; and (b) a first-type protein interaction domain. Further provided herein are methods for treating or preventing an autoimmune disease, a transplant rejection, or graft versus host disease.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: August 15, 2023
    Assignees: TRUSTEES OF BOSTON UNIVERSITY, THE GENERAL HOSPITAL CORPORATION
    Inventors: Mohammadreza Pakyari, Wilson Wong, Atsushi Okuma, Curtis Cetrulo
  • Publication number: 20210113653
    Abstract: The technology described herein is directed to compositions comprising components of multi-component CALs or CARs, e.g., a TCR recognition domain; and one or both of: (a) an intracellular signaling domain; and (b) a first-type protein interaction domain. Further provided herein are methods for treating or preventing an autoimmune disease, a transplant rejection, or graft versus host disease.
    Type: Application
    Filed: October 16, 2020
    Publication date: April 22, 2021
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, THE GENERAL HOSPITAL CORPORATION
    Inventors: Mohammadreza PAKYARI, Wilson WONG, Atsushi OKUMA, Curtis CETRULO
  • Publication number: 20110059050
    Abstract: The invention relates to methods and compositions for stem cell transplantation. Aspects of the invention relate to administering hematopoietic stem cells and mesemchymal cells to a patient.
    Type: Application
    Filed: January 26, 2007
    Publication date: March 10, 2011
    Inventors: Kyle Cetrulo, Curtis Cetrulo