Patents by Inventor Curtis Coughlin, II

Curtis Coughlin, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-oxo-pipecolic acid quantitation by mass spectrometry
    Patent number: 12025596
    Abstract: Methods for determining the presence or amount of oxopiperidine in a biological sample using mass spectrometry. These methods may be used to efficiently and non-invasively diagnose pyridoxine dependent epilepsy (PDE) due to deficient a-aminoadipic-?-semialdehyde (?-AASA) dehydrogenase activity due to mutations in ALDH7A1, resulting in the accumulation of ?1-P6C, P6CH, and 6-Oxo-PIP in biological samples.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: July 2, 2024
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Michael F. Wempe, Johan L. Van Hove, Curtis Coughlin, II
  • 6-OXO-PIPECOLIC ACID QUANTITATION BY MASS SPECTROMETRY
    Publication number: 20220057371
    Abstract: Methods for determining the presence or amount of oxopiperidine in a biological sample using mass spectrometry. These methods may be used to efficiently and non-invasively diagnose pyridoxine dependent epilepsy (PDE) due to deficient a-aminoadipic-?-semialdehyde (?-AASA) dehydrogenase activity due to mutations in ALDH7A1, resulting in the accumulation of ?1-P6C, P6CH, and 6-Oxo-PIP in biological samples.
    Type: Application
    Filed: February 19, 2019
    Publication date: February 24, 2022
    Inventors: Michael F. Wempe, Johan L. Van Hove, Curtis Coughlin, II