Patents by Inventor Curtis Gerald JONES

Curtis Gerald JONES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of detecting platelet activating antibodies that cause heparin-induced thrombocytopenia/thrombosis
    Patent number: 10215767
    Abstract: The present invention provides a method of detecting platelet activation in a patient, the method comprising the steps of a) obtaining a blood sample from a patient suspected of having heparin-induced thrombocytopenia (HIT); b) incubating an effective amount of platelet factor 4 (PF4) with a sample of platelets to yield a sample of PF4-treated platelets; c) contacting the patient blood sample with the PF4-treated platelets; and d) measuring the extent of platelet activation, wherein an increase in platelet activation compared with results obtained using a normal blood sample is indicative of the patient having HIT.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: February 26, 2019
    Assignee: Versiti Blood Research Institute Foundation, Inc.
    Inventors: Richard H. Aster, Daniel W. Bougie, Curtis Gerald Jones, Anand Padmanabhan
  • METHOD OF DETECTING PLATELET ACTIVATING ANTIBODIES THAT CAUSE HEPARIN-INDUCED THROMBOCYTOPENIA/THROMBOSIS
    Publication number: 20180074078
    Abstract: The present invention provides a method of detecting platelet activation in a patient, the method comprising the steps of a) obtaining a blood sample from a patient suspected of having heparin-induced thrombocytopenia (HIT); b) incubating an effective amount of platelet factor 4 (PF4) with a sample of platelets to yield a sample of PF4-treated platelets; c) contacting the patient blood sample with the PF4-treated platelets; and d) measuring the extent of platelet activation, wherein an increase in platelet activation compared with results obtained using a normal blood sample is indicative of the patient having HIT.
    Type: Application
    Filed: November 20, 2017
    Publication date: March 15, 2018
    Inventors: Richard H. Aster, Daniel W. Bougie, Curtis Gerald Jones, Anand Padmanabhan
  • Method of detection of platelet-activating antibodies that cause heparin-induced thrombocytopenia/thrombosis
    Patent number: 9851367
    Abstract: The present invention provides a method of detecting platelet activation in a patient, the method comprising the steps of a) obtaining a blood sample from a patient suspected of having heparin-induced thrombocytopenia (HIT); b) incubating an effective amount of platelet factor 4 (PF4) with a sample of platelets to yield a sample of PF4-treated platelets; c) contacting the patient blood sample with the PF4-treated platelets; and d) measuring the extent of platelet activation, wherein an increase in platelet activation compared with results obtained using a normal blood sample is indicative of the patient having HIT.
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: December 26, 2017
    Assignee: Blood Center Research Foundation
    Inventors: Richard H. Aster, Daniel W. Bougie, Curtis Gerald Jones, Anand Padmanabhan
  • Method of Detection of Platelet-Activating Antibodies That Cause Heparin-Induced Thrombocytopenia/Thrombosis
    Publication number: 20160231338
    Abstract: The present invention provides a method of detecting platelet activation in a patient, the method comprising the steps of a) obtaining a blood sample from a patient suspected of having heparin-induced thrombo-cytopenia (HIT); b) incubating an effective amount of platelet factor 4 (PF4) with a sample of platelets to yield a sample of PF4-treated platelets; c) contacting the patient blood sample with the PF4-treated platelets; and d) measuring the extent of platelet activation, wherein an increase in platelet activation compared with results obtained using a normal blood sample is indicative of the patient having HIT.
    Type: Application
    Filed: October 28, 2014
    Publication date: August 11, 2016
    Inventors: Richard H. ASTER, Daniel W. BOUGIE, Curtis Gerald JONES, Anand PADMANABHAN