Patents by Inventor Curtis Keith

Curtis Keith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20120149900
    Abstract: Fluorinated compounds and methods of making fluorinated compounds are described herein.
    Type: Application
    Filed: January 8, 2010
    Publication date: June 14, 2012
    Inventors: Tobias Ritter, Laura Brass, Curtis Keith, Alan Watson, David J. Greenblatt
  • FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20120095217
    Abstract: Fluorinated compounds and methods of making fluorinated compounds are described herein.
    Type: Application
    Filed: January 8, 2010
    Publication date: April 19, 2012
    Inventors: Tobias Ritter, Laura Brass, Curtis Keith, Alan Watson, David J. Greenblatt
  • METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS
    Publication number: 20120058979
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: November 9, 2011
    Publication date: March 8, 2012
    Applicant: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant R. Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley, Michael S. Slavonic, Brendan Smith, Benjamin A. Auspitz
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Patent number: 8080553
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: December 20, 2011
    Assignee: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant R. Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley, Michael S. Slavonic, Brendan Smith, Benjamin A. Auspitz
  • COMBINATIONS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS
    Publication number: 20110223621
    Abstract: The invention features pharmaceutical compositions that include dipyridamole and a corticosteroid.
    Type: Application
    Filed: March 15, 2011
    Publication date: September 15, 2011
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole W. Hurst, Michael A. Foley
  • Combinations for the treatment of immunoinflammatory disorders
    Patent number: 7915265
    Abstract: The invention features pharmaceutical compositions that include dipyridamole and a corticosteroid.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: March 29, 2011
    Assignee: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole W. Hurst, Michael A. Foley
  • Methods and reagents for the treatment of metabolic disorders
    Patent number: 7795310
    Abstract: The invention features compositions, methods, and kits for the treatment of metabolic disorders such as diabetes and obesity.
    Type: Grant
    Filed: June 30, 2005
    Date of Patent: September 14, 2010
    Assignee: CombinatoRx, Inc.
    Inventors: Margaret S. Lee, Grant R. Zimmermann, Alyce L. Finelli, Daniel Grau, Curtis Keith, M. James Nichols
  • COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20100173881
    Abstract: The invention features methods and compositions for the treatment of immunonflammatory disorders.
    Type: Application
    Filed: January 22, 2010
    Publication date: July 8, 2010
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmerrmann, Curtis Keith, Alexis Borisy
  • COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20080280863
    Abstract: The invention features methods and compositions for the treatment of immunoinflammatory disorders.
    Type: Application
    Filed: February 25, 2008
    Publication date: November 13, 2008
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Screening system for identifying drug-drug interactions and methods of use thereof
    Publication number: 20080194421
    Abstract: The invention features a method of screening for drug-drug interactions using combinational arrays. The method includes the steps of: (a) receiving a test drug from a client; (b) contacting the test drug and at least 200 library drugs from a drug library in an assay under conditions that ensure that each test drug/library drug contacting is segregated from the others; (c) recording the result of the contacting step (b); (d) identifying combinations of drugs that produce a result in the assay that is different from the results produced by either drug of the combination by itself, wherein each identified combination indicates an interaction between the test drug and the library drug of the combination; and (e) communicating the results of the identifying step (d) to the client.
    Type: Application
    Filed: January 24, 2008
    Publication date: August 14, 2008
    Inventors: Alexis Borisy, Daniel Grau, Brent R. Stockwell, Curtis Keith
  • Combinations for the treatment of inflammatory disorders
    Patent number: 7335371
    Abstract: The invention features methods and compositions for the treatment of immunonflammatory disorders.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: February 26, 2008
    Assignee: CombinatoRx, Incorporated
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Anti-scarring drug combinations and use thereof
    Publication number: 20070299043
    Abstract: The present invention provides devices or implants that comprise anti-scarring drug combinations, methods or making such devices or implants, and methods of inhibiting fibrosis between the devices or implants and tissue surrounding the devices or implants. The present invention also provides compositions that comprise anti-fibrotic drug combinations, and their uses in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
    Type: Application
    Filed: April 4, 2007
    Publication date: December 27, 2007
    Inventors: William Hunter, Philip Toleikis, David Gravett, Daniel Grau, Alexis Borisy, Curtis Keith, Benjamin Auspitz, M. Nichols, Edward Jost-Price, George Serbedzija
  • Combinations for the treatment of rheumatoid arthritis
    Publication number: 20070259841
    Abstract: The invention features a method for treating a patient diagnosed with rheumatoid arthritis by systemically administering an azole and a steroid to the patient. The invention also features a pharmaceutical composition containing an azole and a steroid for the treatment of rheumatoid arthritis.
    Type: Application
    Filed: June 13, 2007
    Publication date: November 8, 2007
    Applicant: CombinatoRx, Incorporated
    Inventors: Jason Fong, Edward Jost-Price, Curtis Keith, Palaniyandi Manivasakam, Robyn Sackeyfio, Grant Zimmermann
  • Anti-scarring drug combinations and use thereof
    Publication number: 20070208134
    Abstract: The present invention provides devices or implants that comprise anti-scarring drug combinations, methods or making such devices or implants, and methods of inhibiting fibrosis between the devices or implants and tissue surrounding the devices or implants. The present invention also provides compositions that comprise anti-fibrotic drug combinations, and their uses in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
    Type: Application
    Filed: October 3, 2006
    Publication date: September 6, 2007
    Inventors: William Hunter, Philip Toleikis, David Gravett, Daniel Grau, Alexis Borisy, Curtis Keith, Benjamin Auspitz, M. Nichols, Edward Jost-Price, George Serbedzija
  • Soft tissue implants and drug combination compositions, and use thereof
    Publication number: 20070196421
    Abstract: Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring drug combination in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.
    Type: Application
    Filed: October 3, 2006
    Publication date: August 23, 2007
    Inventors: William Hunter, Philip Toleikis, David Gravett, Daniel Grau, Alexis Borisy, Curtis Keith, Benjamin Auspitz, M. Nichols, Edward Jost-Price, George Serbedzija
  • Implantable sensors, implantable pumps and anti-scarring drug combinations
    Publication number: 20070197957
    Abstract: Pumps and sensors for contact with tissue are used in combination with an anti-scarring agent or a composition that comprises an anti-scarring agent to inhibit scarring that may otherwise occur when the pumps and sensors are implanted within an animal.
    Type: Application
    Filed: October 3, 2006
    Publication date: August 23, 2007
    Inventors: William Hunter, Philip Toleikis, David Gravett, Daniel Grau, Alexis Borisy, Curtis Keith, Benjamin Auspitz, M. Nichols, Edward Jost-Price, George Serbedzija
  • Electrical devices and anti-scarring drug combinations
    Publication number: 20070198063
    Abstract: Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring drug combination or a composition that comprises an anti-scarring drug combination to inhibit scarring that may otherwise occur when the devices are implanted within an animal.
    Type: Application
    Filed: October 3, 2006
    Publication date: August 23, 2007
    Inventors: William Hunter, Philip Toleikis, David Gravett, Daniel Grau, Alexis Borisy, Curtis Keith, Benjamin Auspitz, M. Nichols, Edward Jost-Price, George Serbedzija
  • Combinations for the treatment of immunoinflammatory disorders
    Patent number: 7253155
    Abstract: The invention features a method for treating a patient having an immunoinflammatory disorder, by administering to the patient (i) a tetra-substituted pyrimidopyrimidine, and (ii) a corticosteroid simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit immunoinflammation.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: August 7, 2007
    Assignee: CombinatoRx, Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmerman, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley
  • Combinations for the treatment of noeplastic disorders
    Publication number: 20070099906
    Abstract: The invention features a method for treating a patient having a cancer or other neoplasm by administering to the patient two compounds simultaneously or within 14 days of each other in amounts sufficient to treat the patient.
    Type: Application
    Filed: December 7, 2006
    Publication date: May 3, 2007
    Inventors: Alexis Borisy, Curtis Keith, Michael Foley, Brent Stockwell
  • Combinations of drugs for the treatment of neoplasms
    Publication number: 20070099905
    Abstract: The invention features a method for treating a patient having a cancer or other neoplasm by administering to the patient two compounds simultaneously or within 14 days of each other in amounts sufficient to treat the patient.
    Type: Application
    Filed: October 24, 2006
    Publication date: May 3, 2007
    Inventors: Alexis Borisy, Curtis Keith, Michael Foley, Brent Stockwell, Debra Gaw, M. Nichols, Margaret Lee