Abstract: A system and method of generating an image analysis report relating to an image of a subject. The method includes querying a user for an image description providing locational information regarding the image, querying the user for a physical description providing locational information regarding the subject, and querying the user for a finding description providing selected characteristics of the image. A description set including the user's responses to the queries is stored and processed to generate the report. Any of the querying steps may include providing the user with a limited set of entry options, and some of the entry may be by selecting a location on a graphical map. A second description set relating to a different image of the same or a different subject may also be entered, and the user may be queried for information relating to a causal link between the description sets. A user may be queried for a confidence level of any observation or conclusion.