Abstract: This disclosure relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.

Abstract: Composite components and methods for adding a composite material to a composite component are provided. For example, a method comprises positioning a composite material segment against the composite component to form a component layup; applying an insulating material around at least a portion of the component layup to form an insulated layup; and densifying the insulated layup, where the composite component was previously densified before positioning the composite material segment against the composite component. In some embodiments, the composite material is ceramic matrix composite (CMC) and the composite material segment is a plurality of CMC plies. The composite component may be a CMC gas turbine engine component that comprises an original CMC component and a new CMC material segment joined to the original CMC component through the transfer of silicon between the original CMC component and the new CMC material segment during melt infiltration.

Abstract: Various embodiments of an apparatus, methods, systems and computer program products described herein are directed to an agricultural observation and treatment system and method of operation. The agricultural treatment system may determine a first real-world geo-spatial location of the treatment system. The system can receive captured images depicting real-world agricultural objects of a geographic scene. The system can associate captured images with the determined geo-spatial location of the treatment system. The treatment system can identify, from a group of mapped and indexed images, images having a second real-word geo-spatial location that is proximate with the first real-world geo-spatial location. The treatment system can compare at least a portion of the identified images with at least a portion of the captured images. The treatment system can determine a target object and emit a fluid projectile at the target object using a treatment device.

Abstract: The present disclosure provides a method of facilitating authenticating of users. Further, the method includes initiating, using a processing device, an authentication session for a user for an authentication instance. Further, the method includes identifying, using the processing device, authentication prompts for the authenticating of the user based on the initiating. Further, the method includes transmitting, using a communication device, the authentication prompts to user devices. Further, the method includes receiving, using the communication device, data in response to the authentication prompts from the user devices. Further, the method includes analyzing, using the processing device, the data using machine learning models. Further, the method includes generating, using the processing device, an authentication status for the user based on the analyzing. Further, the method includes terminating, using the processing device, the authentication session based on the generating.

Abstract: The present disclosure provides a method of facilitating authenticating of users. Further, the method includes initiating, using a processing device, an authentication session for a user for an authentication instance. Further, the method includes identifying, using the processing device, authentication prompts for the authenticating of the user based on the initiating. Further, the method includes transmitting, using a communication device, the authentication prompts to user devices. Further, the method includes receiving, using the communication device, data in response to the authentication prompts from the user devices. Further, the method includes analyzing, using the processing device, the data using machine learning models. Further, the method includes generating, using the processing device, an authentication status for the user based on the analyzing. Further, the method includes terminating, using the processing device, the authentication session based on the generating.

Abstract: Disclosed herein are filtration articles comprising a porous ceramic structure comprising a plurality of channels separated by a plurality of porous interior walls, and a nanomembrane disposed on at least a portion of a surface of the porous ceramic structure, wherein the nanomembrane comprises nanoparticles of at least one inorganic oxide, and wherein the nanoparticles are present in a concentration ranging from about 0.001 g/L to about 1 g/L based on the total volume of the porous ceramic structure. Methods for making such filtration articles and methods for filtering a particulate from a fluid using such filtration articles are also disclosed herein.

Abstract: The present invention relates to a porcine parvovirus and porcine reproductive and respiratory syndrome virus vaccine for protecting a subject, preferably swine, against diseases associated with porcine parvovirus and porcine reproductive and respiratory syndrome virus. The present invention further relates to methods of producing immunogenic compositions as well as such immunogenic compositions exhibiting reduced virucidal activity.

Abstract: Apparatus and methods are disclosed which are capable of being used to determine filtration efficiency of a filter body even in a clean state. Methods of determining a filtration efficiency of a filter including forcing an inlet flow comprised of a gas (such as air) flow into the inlet end of the filter at a set flow rate, introducing particles such as smoke particles into the inlet flow, and optically counting the number of particles entering and exiting the filter during a sampling event, such as with diffraction based optical particle counters positioned upstream and downstream of the filter. Preferably the gas flow is a soot-free flow stream which does not load the honeycomb filter body with contaminants that need to be removed or burned out. The filter body can thus remain in an essentially clean state even after testing its filtration efficiency.

Abstract: The present disclosure provides a method of facilitating authenticating of users. Further, the method includes initiating, using a processing device, an authentication session for a user for an authentication instance. Further, the method includes identifying, using the processing device, authentication prompts for the authenticating of the user based on the initiating. Further, the method includes transmitting, using a communication device, the authentication prompts to user devices. Further, the method includes receiving, using the communication device, data in response to the authentication prompts from the user devices. Further, the method includes analyzing, using the processing device, the data using machine learning models. Further, the method includes generating, using the processing device, an authentication status for the user based on the analyzing. Further, the method includes terminating, using the processing device, the authentication session based on the generating.

Abstract: A method of producing bi-modal particles includes the steps of igniting a first precursor gas using a primary burner thereby producing a first plurality of particles of a first size, fluidly transporting the first plurality of particles down a particle tube, igniting a second precursor gas using a secondary burner thereby producing a second plurality of particles of a second size, flowing the second plurality of particles into the first plurality of particles, and capturing the first and second plurality of particles.

Abstract: Shielding a storage device of a storage system from one or more storage performance enhancement procedures (SPEPs) is disclosed. A SPEP can be regarded as a procedure that manipulates data stored via a storage device in a manner that attempts to improve performance of the storage system. As such, SPEPs are generally distinct from basic reading and writing of data that is not associated with storage system performance optimization. A SPEP can typically be effectively run without storage device performance degradation, however some conditions, such as very full drives, etc., can result in substantial storage device performance degradation where one or more SPEP is performed. As such, shielding can restrict permission to perform one or more SPEPs at a storage device expected to, or actually experiencing, a threshold level of performance degradation. Shielding is distinct from conventional techniques marking a drive as failed, failing, etc., as is disclosed herein.

Abstract: Shielding a storage device of a storage system from one or more storage performance enhancement procedures (SPEPs) is disclosed. A SPEP can be regarded as a procedure that manipulates data stored via a storage device in a manner that attempts to improve performance of the storage system. As such, SPEPs are generally distinct from basic reading and writing of data that is not associated with storage system performance optimization. A SPEP can typically be effectively run without storage device performance degradation, however some conditions, such as very full drives, etc., can result in substantial storage device performance degradation where one or more SPEP is performed. As such, shielding can restrict permission to perform one or more SPEPs at a storage device expected to, or actually experiencing, a threshold level of performance degradation. Shielding is distinct from conventional techniques marking a drive as failed, failing, etc., as is disclosed herein.

Abstract: Methods for producing a glass sheet are provided. The methods can include forming a glass ribbon from molten glass, applying a polymer precursor to at least a portion of a first or second major surface of the glass ribbon, curing the polymer precursor to form a polymer coating, and separating the glass ribbon to produce at least one glass sheet. Glass ribbons and glass sheets produced by these methods are also disclosed.

Abstract: Facilitating device compatibility is provided herein. A system can comprise a processor and a memory that stores executable instructions that, when executed by the processor, facilitate performance of operations. The operations can comprise evaluating a parameter of a device to a defined parameter of a device pool based on receipt of a request to add the device to the device pool and based on a determination that a device type of the device does not match a defined device type of the device pool. Further, the operations can comprise either allowing the device to be included in the device pool based on the evaluating, or denying the device to be included in the device pool based on the evaluating. If the inclusion of the device is denied, the operations can comprise providing information indicative of a denial to add the device to the device pool.

Abstract: A method of forming a solid, dense, hermetic lithium-ion electrolyte membrane comprises combing an amorphous, glassy, or low melting temperature solid reactant with a refractory oxide reactant to form a mixture, casting the mixture to form a green body, and sintering the green body to form a solid membrane. The resulting electrolyte membranes can be incorporated into lithium-ion batteries.

Abstract: Disclosed herein are filtration articles comprising a porous ceramic structure comprising a plurality of channels separated by a plurality of porous interior walls, and a nanomembrane disposed on at least a portion of a surface of the porous ceramic structure, wherein the nanomembrane comprises nanoparticles of at least one inorganic oxide, and wherein the nanoparticles are present in a concentration ranging from about 0.001 g/L to about 1 g/L based on the total volume of the porous ceramic structure. Methods for making such filtration articles and methods for filtering a particulate from a fluid using such filtration articles are also disclosed herein.

Abstract: Solid lithium-ion ceramic electrolyte membranes have an average thickness of less than 200 micrometers. A constituent electrolyte material has an average grain size of less than 10 micrometers. The solid lithium-ion ceramic electrolyte is free-standing. Alternatively, solid lithium-ion electrolyte membranes have a composition represented by Li1+x?yMxM?2?x?yM?y(PO4)3, where M is a 3+ ion, M? is a 4+ ion, M? is a 5+ ion, 0?x?2 and 0?y?2.

Abstract: Disclosed herein are filtration articles comprising a porous ceramic structure comprising a plurality of channels separated by a plurality of porous interior walls, and a nanomembrane disposed on at least a portion of a surface of the porous ceramic structure, wherein the nanomembrane comprises nanoparticles of at least one inorganic oxide, and wherein the nanoparticles are present in a concentration ranging from about 0.001 g/L to about 1 g/L based on the total volume of the porous ceramic structure. Methods for making such filtration articles and methods for filtering a particulate from a fluid using such filtration articles are also disclosed herein.