Patents by Inventor Curtis Thorne

Curtis Thorne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of using an antibody to inhibit WNT-mediated signaling in cancer
    Patent number: 9175090
    Abstract: The present invention is directed to monoclonal antibodies and fragments thereof directed to LRP5/6 that find use in the prevention and treatment of cardiac remodeling and cancer. Also disclosed are methods for using such monoclonal antibodies in the prevention and treatment of such diseases.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: November 3, 2015
    Assignee: VANDERBILT UNIVERSITY
    Inventors: Ethan Lee, Pampee P. Young, Josiane Eid, Robert Carnahan, Curtis Thorne, Kelly Meyers
  • Pyrvinium For The Treatment of Cancer
    Publication number: 20090099062
    Abstract: The present invention concerns a pyrvinium compound or an analog thereof for the treatment of cancers. This compound inhibits Wnt activity in the cells of cancers such as adrenocortical, hepatocellular, hepatoblastoma, malignant melanoma, ovarian, Wilm's tumor, Barrett's esophageal, glioma, bladder, breast, gastric, head & neck, lung cell, mesothelioma, and cervical cancers. The present invention also provides a method for assaying for compounds that alter Wnt pathway activity. Also provided are methods for treating Wnt-related non-cancer disease states.
    Type: Application
    Filed: May 29, 2008
    Publication date: April 16, 2009
    Inventors: Ethan Lee, Laura Lee, Curtis Thorne, Emilios Tahinci, Kelly Christian Meyers