Patents by Inventor Cuthbert O. Simpkins

Cuthbert O. Simpkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10716756
    Abstract: A pharmaceutical composition comprising a lipid component, an amphiphilic emulsifier, a polar liquid carrier, and one or more electrolytes, where the amphiphilic emulsifier forms lipid carrying micelles having a lipophilic core comprising the lipid component in the polar liquid carrier, and/or liposomes organized as a lipid bilayer and/or other particle configurations. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating ischemic conditions with reduced reperfusion injury.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: July 21, 2020
    Assignee: Vivacelle Bio, Inc.
    Inventor: Cuthbert O. Simpkins
  • Publication number: 20190151244
    Abstract: A pharmaceutical composition comprising a lipid component, an amphiphilic emulsifier, a polar liquid carrier, and one or more electrolytes, where the amphiphilic emulsifier forms lipid carrying micelles having a lipophilic core comprising the lipid component in the polar liquid carrier, and/or liposomes organized as a lipid bilayer and/or other particle configurations. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating ischemic conditions with reduced reperfusion injury.
    Type: Application
    Filed: June 15, 2017
    Publication date: May 23, 2019
    Applicant: VIVACELLE BIO, INC.
    Inventor: Cuthbert O. SIMPKINS
  • Publication number: 20190015327
    Abstract: A pharmaceutical composition comprising a lipid component, an amphiphilic emulsifier, a polar liquid carrier, and one or more electrolytes, where the amphiphilic emulsifier forms lipid carrying micelles or liposomes having a lipophilic core comprising the lipid component in the polar liquid carrier, and the micelles or liposomes have an average diameter between 90 nm and 120 nm and are stable for at least 4 weeks at room temperature. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply including but not limited to restoring normal cardiac rhythm after cardiac arrest or arrhythmia and to raise the blood pressure and correct hypovolemia.
    Type: Application
    Filed: September 14, 2016
    Publication date: January 17, 2019
    Inventor: Cuthbert O. SIMPKINS
  • Patent number: 9622968
    Abstract: A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form free-moving, optionally lipid-carrying, micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure and correct hypovolemia.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: April 18, 2017
    Assignee: VIVACELLE BIO, INC.
    Inventor: Cuthbert O. Simpkins
  • Patent number: 9439855
    Abstract: A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form free-moving, optionally lipid-carrying, micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure and correct hypovolemia.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: September 13, 2016
    Assignee: Vivacelle Bio, Inc.
    Inventor: Cuthbert O. Simpkins
  • Patent number: 9387162
    Abstract: A pharmaceutical composition comprising a lipid component; an amphiphilic emulsifier; and a polar liquid carrier. The lipid component and the amphiphilic emulsifier form free-moving lipid-carrying micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: July 12, 2016
    Assignee: VIVACELLE BIO, INC.
    Inventor: Cuthbert O. Simpkins
  • Publication number: 20150064259
    Abstract: A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form free-moving, optionally lipid-carrying, micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure and correct hypovolemia.
    Type: Application
    Filed: November 6, 2014
    Publication date: March 5, 2015
    Inventor: Cuthbert O. SIMPKINS
  • Publication number: 20150064266
    Abstract: A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form free-moving, optionally lipid-carrying, micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure and correct hypovolemia.
    Type: Application
    Filed: November 6, 2014
    Publication date: March 5, 2015
    Inventor: Cuthbert O. SIMPKINS
  • Patent number: 8906855
    Abstract: A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form free-moving, optionally lipid-carrying, micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure and correct hypovolemia.
    Type: Grant
    Filed: August 9, 2013
    Date of Patent: December 9, 2014
    Assignee: Vivacelle Bio, Inc.
    Inventor: Cuthbert O. Simpkins
  • Publication number: 20140112961
    Abstract: A pharmaceutical composition comprising a lipid component; an amphiphilic emulsifier; and a polar liquid carrier. The lipid component and the amphiphilic emulsifier form free-moving lipid-carrying micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure.
    Type: Application
    Filed: November 21, 2013
    Publication date: April 24, 2014
    Inventor: Cuthbert O. SIMPKINS
  • Patent number: 8618056
    Abstract: A pharmaceutical composition comprising a lipid component; an amphiphilic emulsifier; and a polar liquid carrier. The lipid component and the amphiphilic emulsifier form free-moving lipid-carrying micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure.
    Type: Grant
    Filed: October 14, 2011
    Date of Patent: December 31, 2013
    Inventor: Cuthbert O. Simpkins
  • Publication number: 20130323308
    Abstract: A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form free-moving, optionally lipid-carrying, micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure and correct hypovolemia.
    Type: Application
    Filed: August 9, 2013
    Publication date: December 5, 2013
    Inventor: Cuthbert O. SIMPKINS
  • Patent number: 8569236
    Abstract: A method for treating conditions related to lack of blood supply with a lipid based resuscitation fluid is disclosed. The resuscitation fluid contains a lipid component and an aqueous carrier. The lipid component forms an emulsion with the aqueous carrier. The resuscitation fluid can be used to increase the blood pressure and to carry oxygen to tissues. The resuscitation fluid can also be used for preserving the biological integrity of donor organs for transplantation.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: October 29, 2013
    Inventor: Cuthbert O. Simpkins
  • Publication number: 20130095192
    Abstract: A method for treating conditions related to lack of blood supply with a lipid based resuscitation fluid is disclosed. The resuscitation fluid contains a lipid component and an aqueous carrier. The lipid component forms an emulsion with the aqueous carrier. The resuscitation fluid can be used to increase the blood pressure and to carry oxygen to tissues. The resuscitation fluid can also be used for preserving the biological integrity of donor organs for transplantation.
    Type: Application
    Filed: December 7, 2012
    Publication date: April 18, 2013
    Inventor: Cuthbert O. SIMPKINS
  • Patent number: 8367613
    Abstract: A method for treating conditions related to lack of blood supply with a lipid based resuscitation fluid is disclosed. The resuscitation fluid contains a lipid component and an aqueous carrier. The lipid component forms an emulsion with the aqueous carrier. The resuscitation fluid can be used to increase the blood pressure and to carry oxygen to tissues. The resuscitation fluid can also be used for preserving the biological integrity of donor organs for transplantation.
    Type: Grant
    Filed: October 12, 2011
    Date of Patent: February 5, 2013
    Inventor: Cuthbert O. Simpkins
  • Patent number: 8198243
    Abstract: A method for treating conditions related to lack of blood supply with a lipid based resuscitation fluid is disclosed. The resuscitation fluid contains a lipid component and an aqueous carrier. The lipid component forms an emulsion with the aqueous carrier. The resuscitation fluid can be used to increase the blood pressure and to carry oxygen to tissues. The resuscitation fluid can also be used for preserving the biological integrity of donor organs for transplantation.
    Type: Grant
    Filed: October 12, 2011
    Date of Patent: June 12, 2012
    Inventor: Cuthbert O. Simpkins
  • Publication number: 20120087956
    Abstract: A pharmaceutical composition comprising a lipid component; an amphiphilic emulsifier; and a polar liquid carrier. The lipid component and the amphiphilic emulsifier form free-moving lipid-carrying micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure.
    Type: Application
    Filed: October 14, 2011
    Publication date: April 12, 2012
    Inventor: Cuthbert O. SIMPKINS
  • Publication number: 20120034277
    Abstract: A method for treating conditions related to lack of blood supply with a lipid based resuscitation fluid is disclosed. The resuscitation fluid contains a lipid component and an aqueous carrier. The lipid component forms an emulsion with the aqueous carrier. The resuscitation fluid can be used to increase the blood pressure and to carry oxygen to tissues. The resuscitation fluid can also be used for preserving the biological integrity of donor organs for transplantation.
    Type: Application
    Filed: October 12, 2011
    Publication date: February 9, 2012
    Inventor: Cuthbert O. SIMPKINS
  • Publication number: 20120028235
    Abstract: A method for treating conditions related to lack of blood supply with a lipid based resuscitation fluid is disclosed. The resuscitation fluid contains a lipid component and an aqueous carrier. The lipid component forms an emulsion with the aqueous carrier. The resuscitation fluid can be used to increase the blood pressure and to carry oxygen to tissues. The resuscitation fluid can also be used for preserving the biological integrity of donor organs for transplantation.
    Type: Application
    Filed: October 12, 2011
    Publication date: February 2, 2012
    Inventor: Cuthbert O. SIMPKINS
  • Patent number: 8063020
    Abstract: A method for treating conditions related to lack of blood supply with a lipid based resuscitation fluid is disclosed. The resuscitation fluid contains a lipid component and an aqueous carrier. The lipid component forms an emulsion with the aqueous carrier. The resuscitation fluid can be used to increase the blood pressure and to carry oxygen to tissues. The resuscitation fluid can also be used for preserving the biological integrity of donor organs for transplantation.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: November 22, 2011
    Inventor: Cuthbert O. Simpkins