Patents by Inventor Cvetko Nikolic

Cvetko Nikolic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11445975
    Abstract: The present disclosure provides systems and methods for predicting fluid responsiveness. Embodiments include sensors configured to obtain a high-resolution electrocardiogram signal and a computer system connected to the sensors that detects and processes changes in at least one of length, amplitude, slope, area, depth, and height of at least one of P, Q, R, S, T, and U complex of the electrocardiogram signal caused by the influence of physiological variables on each other to create a prognostic index. The prognostic index of the changes in the electrocardiogram signal may then be used to generate a fluid responsiveness prediction. The fluid responsiveness prediction may then be used to control fluid administration for patients that are receiving anesthesia during surgery or that are critically ill or unresponsive. Disclosed embodiments may also be used as a diagnostic tool for athletes during training, who are undergoing endurance tests, for bike riders, etc.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: September 20, 2022
    Assignee: CN MEDICAL RESEARCH LLC
    Inventor: Cvetko Nikolic
  • Patent number: 11284836
    Abstract: The present disclosure provides systems and methods for predicting fluid responsiveness. Embodiments include sensors configured to obtain a high-resolution electrocardiogram signal and a computer system connected to the sensors, the computer system including a memory, a processor, and a display device. Computer system may be configured to receive the electrocardiogram signal from the sensors. Processor may be configured to detect and process changes in at least one of length, amplitude, slope, area, depth, and height of at least one of P, Q, R, S, T, and U complex of the electrocardiogram signal caused by the influence of physiological variables on each other to create a prognostic index. Processor may be further configured to analyze, quantify, and combine the prognostic index of the changes in the electrocardiogram signal and generate a fluid responsiveness prediction. Display device may display the results of the fluid responsiveness prediction.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: March 29, 2022
    Assignee: CN MEDICAL RESEARCH LLC
    Inventor: Cvetko Nikolic
  • Publication number: 20190046113
    Abstract: The present disclosure provides systems and methods for predicting fluid responsiveness. Embodiments include sensors configured to obtain a high-resolution electrocardiogram signal and a computer system connected to the sensors that detects and processes changes in at least one of length, amplitude, slope, area, depth, and height of at least one of P, Q, R, S, T, and U complex of the electrocardiogram signal caused by the influence of physiological variables on each other to create a prognostic index. The prognostic index of the changes in the electrocardiogram signal may then be used to generate a fluid responsiveness prediction. The fluid responsiveness prediction may then be used to control fluid administration for patients that are receiving anesthesia during surgery or that are critically ill or unresponsive. Disclosed embodiments may also be used as a diagnostic tool for athletes during training, who are undergoing endurance tests, for bike riders, etc.
    Type: Application
    Filed: October 15, 2018
    Publication date: February 14, 2019
    Inventor: Cvetko Nikolic
  • Publication number: 20170027502
    Abstract: The present disclosure provides systems and methods for predicting fluid responsiveness. Embodiments include sensors configured to obtain a high-resolution electrocardiogram signal and a computer system connected to the sensors, the computer system including a memory, a processor, and a display device. Computer system may be configured to receive the electrocardiogram signal from the sensors. Processor may be configured to detect and process changes in at least one of length, amplitude, slope, area, depth, and height of at least one of P, Q, R, S, T, and U complex of the electrocardiogram signal caused by the influence of physiological variables on each other to create a prognostic index. Processor may be further configured to analyze, quantify, and combine the prognostic index of the changes in the electrocardiogram signal and generate a fluid responsiveness prediction. Display device may display the results of the fluid responsiveness prediction.
    Type: Application
    Filed: July 27, 2016
    Publication date: February 2, 2017
    Applicant: CN MEDICAL RESEARCH LLC
    Inventor: Cvetko Nikolic
  • Patent number: 4243498
    Abstract: A fluid bed electrolysis process is provided for the recovery of nickel from nickel-containing solution, e.g., leach solution, in which a fluid bed of substantially pure nickel particles or pellets of size ranging from about 150 to 2000 microns is employed, the fluid bed being preferably formed of reduced nickel oxide, such as hydrogen-reduced nickel oxide.
    Type: Grant
    Filed: February 16, 1979
    Date of Patent: January 6, 1981
    Assignee: Amax Inc.
    Inventors: William G. Sherwood, Donald R. Hodges, Cvetko Nikolic
  • Patent number: 4240886
    Abstract: A fluid bed electrolysis system and process are provided for efficiently removing electroplatable metal ions from an electrolyte, the system utilizing a cell having an axially disposed anode surrounded by a cathode, the anode being partitioned from the cathode by a porous diaphragm. The porous diaphragm defines an anode chamber surrounded by an annular cathode chamber, the annular cathode chamber being adapted to support a fluidizable cathode bed of electrically conductive particulate material, the system having electrolyte circulating means for recirculating electrolyte through said cell and for maintaining said electrically conductive particulate material in an electrochemically active fluidized state, including means for disengaging gas bubbles from said circulated solution formed during electrolysis.
    Type: Grant
    Filed: February 16, 1979
    Date of Patent: December 23, 1980
    Assignee: Amax Inc.
    Inventors: Donald R. Hodges, William G. Sherwood, Cvetko Nikolic
  • Patent number: 4241031
    Abstract: A process is provided for leaching nickeliferous sulfide material, such as NiS precipitate and thermally activated nickel sulfide material, e.g., nickel matte, the process comprising subjecting nickeliferous sulfide material in the finely divided state to leaching in hydrochloric acid of concentration ranging from about 3 N to 8 N at a temperature of over 50.degree. C., the temperature and acid concentration being selected to dissolve at least about 50% by weight of the total contained nickel.
    Type: Grant
    Filed: February 16, 1979
    Date of Patent: December 23, 1980
    Assignee: Amax Inc.
    Inventors: Gustavo A. Meyer, John R. Carlberg, Cvetko Nikolic
  • Patent number: 4202752
    Abstract: A fluid bed electrolysis cell and system are provided for efficiently extracting electroplatable metal ions from an electrolyte, the cell employed having preferably a plurality of anodes and cathodes concentrically disposed relative to each other, each of the anodes being partitioned from each of the cathodes by a porous diaphragm such as to define a plurality of anode chambers and cathode chambers. Each of the cathode chambers are adapted to support a fluidizable cathode bed of electrically conductive particulate material, e.g., powdered nickel, copper, and the like.
    Type: Grant
    Filed: April 3, 1979
    Date of Patent: May 13, 1980
    Assignee: Amax Inc.
    Inventors: William G. Sherwood, Donald R. Hodges, Cvetko Nikolic