Patents by Inventor Cynthia Anne Fink

Cynthia Anne Fink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multicyclic compounds and methods of their use
    Patent number: 8772291
    Abstract: This invention relates to multicyclic compounds, pharmaceutical compositions comprising them, and methods of their use in, for example, the treatment of cognitive disorders.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: July 8, 2014
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Joseph Barbosa, Li Dong, Cynthia Anne Fink, Jiancheng Wang, G. Gregory Zipp
  • MULTICYCLIC COMPOUNDS AND METHODS OF THEIR USE
    Publication number: 20100081691
    Abstract: This invention relates to multicyclic compounds, pharmaceutical compositions comprising them, and methods of their use in, for example, the treatment of cognitive disorders.
    Type: Application
    Filed: December 8, 2009
    Publication date: April 1, 2010
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: Joseph Barbosa, Li Dong, Cynthia Anne Fink, Jiancheng Wang, G. Gregory Zipp
  • METHODS OF TREATING SCHIZOPHRENIA
    Publication number: 20090306100
    Abstract: This invention relates to methods for treating, managing and preventing cognitive impairment associated with various diseases and disorders, age-associated memory impairment, and dementia.
    Type: Application
    Filed: June 15, 2009
    Publication date: December 10, 2009
    Inventors: Joseph Barbosa, Li Dong, Cynthia Anne Fink, Thomas Herbert Lanthom, Jian Cheng Wang, G. Gregory Zipp
  • (R)-PHENYL(HETEROCYCLE)METHANOL-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF THEIR USE
    Publication number: 20090286820
    Abstract: Multicyclic compounds, pharmaceutical compositions comprising them, and methods of their use are described.
    Type: Application
    Filed: May 19, 2009
    Publication date: November 19, 2009
    Inventors: Joseph Barbosa, Yingzhi Bi, Cynthia Anne Fink, Michael Alan Green, Jian Cheng Wang
  • (S)-PHENYL(HETEROCYCLE)METHANOL-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF THEIR USE
    Publication number: 20090181992
    Abstract: Multicyclic compounds and pharmaceutical compositions comprising them are described, along with methods of their use in the treatment of diseases such as age-associated memory impairment, Alzheimer's disease, Attention-Deficit/Hyperactivity Disorder (ADD/ADHD), autism, Down syndrome, Fragile X syndrome, Huntington's disease, Parkinson's disease, and schizophrenia.
    Type: Application
    Filed: March 24, 2009
    Publication date: July 16, 2009
    Inventors: Joseph Barbosa, Yingzhi Bi, Cynthia Anne Fink, Michael Alan Green, Jian Cheng Wang
  • Methods of Treating Cognitive Impairment and Dementia
    Publication number: 20080153811
    Abstract: This invention relates to methods for treating, managing and preventing cognitive impairment associated with various diseases and disorders, age-associated memory impairment, and dementia.
    Type: Application
    Filed: November 5, 2007
    Publication date: June 26, 2008
    Inventors: Joseph Barbosa, Li Dong, Cynthia Anne Fink, Thomas Herbert Lanthorn, Jian Cheng Wang, G. Gregory Zipp
  • (S)-PHENYL(HETEROCYCLE)METHANOL-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF THEIR USE
    Publication number: 20080146600
    Abstract: Multicyclic compounds, pharmaceutical compositions comprising them, and methods of their use are described.
    Type: Application
    Filed: November 5, 2007
    Publication date: June 19, 2008
    Inventors: Joseph Barbosa, Yingzhi Bi, Cynthia Anne Fink, Michael Alan Green, Jian Cheng Wang
  • (R)-PHENYL(HETEROCYCLE)METHANOL-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF THEIR USE
    Publication number: 20080146596
    Abstract: Multicyclic compounds, pharmaceutical compositions comprising them, and methods of their use are described.
    Type: Application
    Filed: November 5, 2007
    Publication date: June 19, 2008
    Inventors: Joseph Barbosa, Yingzhi Bi, Cynthia Anne Fink, Michael Alan Green, Jian Cheng Wang
  • Amine-linked Multicyclic Compounds and Methods of Their Use
    Publication number: 20080139598
    Abstract: This invention relates to multicyclic compounds, pharmaceutical compositions comprising them, and methods of their use.
    Type: Application
    Filed: November 5, 2007
    Publication date: June 12, 2008
    Inventors: Joseph Barbosa, Yingzhi Bi, Cynthia Anne Fink, Jian Cheng Wang
  • Dipeptide derivatives
    Patent number: 6992105
    Abstract: Compounds of the formula wherein R, R1, COOR2, R3–R7, alk, and X have meaning as defined, such being useful as dual inhibitors of angiotensin converting enzyme and neutral endopeptidase, as well as inhibitors of endothelin converting enzyme.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: January 31, 2006
    Assignee: Novartis AG
    Inventor: Cynthia Anne Fink
  • Pyrane derivatives as both ace-and nep-inhibitors
    Publication number: 20040266698
    Abstract: Compounds of the formula (I), wherein R1, R1-R7 and alk have meaning as defined, pharmaceutical compositions thereof, and use thereof for the treatment and/or prevention of cardiovascular disorders responsive to ACE and NEP inhibition and/or ECE inhibition.
    Type: Application
    Filed: February 24, 2004
    Publication date: December 30, 2004
    Inventor: Cynthia Anne Fink
  • Dipeptide derivatives
    Publication number: 20040235754
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: July 2, 2004
    Publication date: November 25, 2004
    Inventor: Cynthia Anne Fink
  • Dipeptide derivatives
    Patent number: 6777443
    Abstract: Compounds of the formula wherein R, R1, COOR2, R3-R7, alk, and X have meaning as defined, such being useful as dual inhibitors of angiotensin converting enzyme and neutral endopeptidase, as well as inhibitors of endothelin converting enzyme.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: August 17, 2004
    Assignee: Novartis AG
    Inventor: Cynthia Anne Fink
  • Certain thiol inhibitors of endothelin-converting enzyme
    Patent number: 6613782
    Abstract: Disclosed as endothelin converting enzyme inhibitors are the compounds of the formula wherein the variables have the meanings as defined hereinbefore.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: September 2, 2003
    Assignee: Novartis AG
    Inventors: Stéphane De Lombaert, Cynthia Anne Fink, Fariborz Firooznia, Denton Wade Hoyer, Arco Yingcheu Jeng
  • Certain heteroaryl substituted thiol inhibitors of endothelin-converting enzyme
    Publication number: 20030018057
    Abstract: Novel thiol derivatives of formula I 1
    Type: Application
    Filed: June 13, 2002
    Publication date: January 23, 2003
    Inventors: Cynthia Anne Fink, Faribroz Firooznia
  • Dipeptide derivatives
    Publication number: 20020183260
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: May 9, 2002
    Publication date: December 5, 2002
    Inventor: Cynthia Anne Fink
  • Certain heteroaryl substituted thiol inhibitors of endothelin-converting enzyme
    Patent number: 6426354
    Abstract: Novel thiol derivatives of formula I or of the formula Ia wherein the variables have the meanings as defined hereinbefore.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: July 30, 2002
    Assignee: Novartis AG
    Inventors: Cynthia Anne Fink, Fariborz Firooznia
  • Certain thiol inhibitors of endothelin-converting enzyme
    Patent number: 6423727
    Abstract: Disclosed as endothelin converting enzyme inhibitors are the compounds of the formula wherein the variables have the meanings as defined hereinbefore.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: July 23, 2002
    Assignee: Novartis AG
    Inventors: Stéphane De Lombaert, Cynthia Anne Fink, Fariborz Firooznia, Denton Wade Hoyer, Arco Yingcheu Jeng
  • Certain thiol inhibitors of endothelin-converting enzyme
    Publication number: 20020082218
    Abstract: Disclosed as endothelin converting enzyme inhibitors are the compounds of the formula 1
    Type: Application
    Filed: February 21, 2002
    Publication date: June 27, 2002
    Inventors: Stephane De Lombaert, Cynthia Anne Fink, Fariborz Firooznia, Denton Wade Hoyer, Arco Yingcheu Jeng
  • Cyclic amino acid derivatives
    Patent number: 5668158
    Abstract: Disclosed are the compounds of formula I ##STR1## wherein R represents hydrogen, lower alkyl, carbocyclic or heterocyclic aryl-lower alkyl or cycloalkyl-lower alkyl;R.sub.1 represents hydrogen, lower alkyl, cycloalkyl, carbocyclic aryl or heterocyclic aryl, or biaryl;R.sub.3 represents hydrogen or acyl;R.sub.4 represents hydrogen, lower alkyl, carbocyclic or heterocyclic aryl, carbocyclic or heterocyclic aryl-lower alkyl, cycloalkyl, cycloalkyl-lower alkyl, biaryl or biaryl-lower alkyl;R.sub.5 represents hydrogen or lower alkyl; or R.sub.4 and R.sub.
    Type: Grant
    Filed: February 14, 1996
    Date of Patent: September 16, 1997
    Assignee: Novartis Corporation
    Inventor: Cynthia Anne Fink