Patents by Inventor Cynthia Bamdad

Cynthia Bamdad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR MAKING PLURIPOTENT STEM CELLS
    Publication number: 20240368578
    Abstract: The present application discloses a method for inducing cells to gain characteristics of naïve stem cell state comprising culturing the cells in the presence of a MUC1* activator.
    Type: Application
    Filed: June 13, 2024
    Publication date: November 7, 2024
    Inventor: Cynthia Bamdad
  • DIAGNOSTIC METHODS USING ANTI-MUC1* ANTIBODIES
    Publication number: 20240352149
    Abstract: The present application discloses a method of determining suitability of treating a patient suffering from cancer or metastasis of cancer characterized by aberrant expression of MUC1, with a MUC1* targeting therapeutic.
    Type: Application
    Filed: March 21, 2024
    Publication date: October 24, 2024
    Inventor: Cynthia Bamdad
  • Chimeric antigen receptor compositions and methods for treating MUC1* diseases
    Patent number: 12115192
    Abstract: Disclosed herein are chimeric antigen receptors (CARs) that target MUC1*. In some embodiments, the CARs have been optimized to reduce T cell exhaustion.
    Type: Grant
    Filed: February 1, 2024
    Date of Patent: October 15, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Methods for deriving dopaminergic neurons from pluripotent stem cells
    Patent number: 12104170
    Abstract: The present application discloses a method of producing dopaminergic neurons from human stem cells by adding or increasing concentration of vitamin into neuro basal media at approximately Day 20+/?3 of a protocol for differentiating pluripotent stem cells into dopaminergic neurons.
    Type: Grant
    Filed: June 28, 2021
    Date of Patent: October 1, 2024
    Inventors: Cynthia Bamdad, Kevin R. Yi, Scott T. Moe, Thomas Jeon
  • METHOD OF SCREENING FOR AGENTS FOR DIFFERENTIATING STEM CELLS
    Publication number: 20240307359
    Abstract: The present application discloses a method for identifying an agent for the treatment or prevention of cancer or metastatic cancer comprising the steps of contacting stem cell with a potential agent, and identifying an agent that induces differentiation, or inhibits stem cell pluripotency or growth of the stem cell, wherein such agent is determined to be an anti-cancer agent.
    Type: Application
    Filed: January 19, 2024
    Publication date: September 19, 2024
    Inventors: Cynthia Bamdad, Scott Moe
  • HUMANIZED ANTI-MUC1* ANTIBODIES AND DIRECT USE OF CLEAVAGE ENZYME
    Publication number: 20240299507
    Abstract: The present application discloses humanized antibodies and antibody like proteins and fragments thereof and the use of proteolytic cleavage enzymes.
    Type: Application
    Filed: January 16, 2024
    Publication date: September 12, 2024
    Inventor: Cynthia Bamdad
  • NUCLEIC ACID ENCODING GENETICALLY ENGINEERED GROWTH FACTOR VARIANTS
    Publication number: 20240294590
    Abstract: The present application discloses a recombinantly made protein construct that preferentially forms multimers.
    Type: Application
    Filed: April 19, 2024
    Publication date: September 5, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • NME INHIBITORS AND METHODS OF USING NME INHIBITORS
    Publication number: 20240277803
    Abstract: The present application discloses inhibitors of NME family of proteins.
    Type: Application
    Filed: February 12, 2024
    Publication date: August 22, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • CHIMERIC ANTIGEN RECEPTOR COMPOSITIONS AND METHODS FOR TREATING MUC1* DISEASES
    Publication number: 20240261406
    Abstract: Disclosed herein are chimeric antigen receptors (CARs) that target MUC1*. In some embodiments, the CARs have been optimized to reduce T cell exhaustion.
    Type: Application
    Filed: January 9, 2024
    Publication date: August 8, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • CHIMERIC ANTIGEN RECEPTOR COMPOSITIONS AND METHODS FOR TREATING MUC1* DISEASES
    Publication number: 20240261331
    Abstract: Disclosed herein are chimeric antigen receptors (CARs) that target MUC1*. In some embodiments, the CARs have been optimized to reduce T cell exhaustion.
    Type: Application
    Filed: February 1, 2024
    Publication date: August 8, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Method for making pluripotent stem cells
    Patent number: 12049618
    Abstract: The present application discloses a method for inducing cells to gain characteristics of naïve stem cell state comprising culturing the cells in the presence of a MUC1* activator.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: July 30, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventor: Cynthia Bamdad
  • Anti-NME antibody and method of treating cancer or cancer metastasis
    Patent number: 12049514
    Abstract: The present application discloses anti-NME antibodies and their use in treating or preventing diseases.
    Type: Grant
    Filed: June 8, 2021
    Date of Patent: July 30, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • MEDIA FOR STEM CELL PROLIFERATION AND INDUCTION
    Publication number: 20240247229
    Abstract: The present application discloses a cell culture media for growth, maintenance and induction of reversion to a less mature state of a cell comprising a MUC1* activating ligand.
    Type: Application
    Filed: January 3, 2024
    Publication date: July 25, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Anti-NME antibody and method of treating cancer or cancer metastasis
    Patent number: 12037413
    Abstract: The present application discloses anti-NME antibodies and their use in treating or preventing diseases.
    Type: Grant
    Filed: August 3, 2021
    Date of Patent: July 16, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Humanized anti-MUC1* antibodies
    Patent number: 12006371
    Abstract: The present application discloses humanized antibodies and antibody like proteins and fragments thereof.
    Type: Grant
    Filed: August 4, 2022
    Date of Patent: June 11, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Diagnostic methods using anti-MUC1* antibodies
    Patent number: 11976132
    Abstract: The present application discloses a method of determining suitability of treating a patient suffering from cancer or metastasis of cancer characterized by aberrant expression of MUC1, with a MUC1* targeting therapeutic.
    Type: Grant
    Filed: February 26, 2019
    Date of Patent: May 7, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventor: Cynthia Bamdad
  • Media for stem cell proliferation and induction
    Patent number: 11976295
    Abstract: The present application discloses a cell culture media for growth, maintenance and induction of reversion to a less mature state of a cell comprising a MUC1* activating ligand.
    Type: Grant
    Filed: January 12, 2023
    Date of Patent: May 7, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Method of screening for agents for differentiating stem cells
    Patent number: 11931347
    Abstract: The present application discloses a method for identifying an agent for the treatment or prevention of cancer or metastatic cancer comprising the steps of contacting stem cell with a potential agent, and identifying an agent that induces differentiation, or inhibits stem cell pluripotency or growth of the stem cell, wherein such agent is determined to be an anti-cancer agent.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: March 19, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Scott Moe
  • Humanized anti-MUC1* antibodies
    Patent number: 11897967
    Abstract: The present application discloses humanized antibodies and antibody like proteins and fragments thereof.
    Type: Grant
    Filed: August 4, 2022
    Date of Patent: February 13, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • MUC1* ANTIBODIES
    Publication number: 20230295340
    Abstract: The present describes monoclonal antibodies.
    Type: Application
    Filed: December 6, 2022
    Publication date: September 21, 2023
    Inventors: Cynthia Bamdad, Sanjeev Mahanta