Patents by Inventor Cynthia Berlinicke

Cynthia Berlinicke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED 4-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)THIOPHENE-2-CARBOXAMIDE DERIVATIVES AND USE THEREOF
    Publication number: 20230382904
    Abstract: Provided herein are 4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)thiophene-2-carboxamide and 4-([1,2,4]triazolo[1,5-a]pyridin-7-yl)thiophene-2-carboxamide derivatives. Such compounds are useful, for example, for the treatment and/or prevention of neurodegenerative diseases or disorders such as ophthalmological neurodegenerative disorders. This disclosure also features compositions containing the same as well as methods of using and making the same.
    Type: Application
    Filed: October 12, 2021
    Publication date: November 30, 2023
    Inventors: Amit Patel, Donald Zack, Derek Welsbie, Cynthia Berlinicke, Brendan N. Lilley, Byung-Jin Kim, Hartmut Schirok, William Schubert, Michael Koch, Lionel Nicolas, Carsten Terjung, Mario Lobell, Simon Holton, Natalia Jungmann
  • SUBSTITUTED 2-AMINO-PYRAZOLYL-[1,2,4]TRIAZOLO[1,5A]PYRIDINE DERIVATIVES AND USE THEREOF
    Publication number: 20230086702
    Abstract: Provided herein are 2-amino-pyrazolyl-[1,2,4]triazolo [1,5a]pyridine derivatives. Such compounds are useful, for example, for the treatment and/or prevention of neurodegenerative diseases or disorders such as ophthalmological neurodegenerative disorders. This disclosure also features compositions containing the same as well as methods of using and making the same.
    Type: Application
    Filed: April 20, 2020
    Publication date: March 23, 2023
    Inventors: Hartmut Schirok, William Schubert, Michael Koch, Lionel Nicolas, Carsten Terjung, Mario Lobell, Simon Holton, Natalia Jungmann, Derek Welsbie, Donald Zack, Cynthia Berlinicke, Amit Patel, Brendan N. Lilley, Byung-Jin Kim
  • POLY(Beta-AMINO ESTER) NANOPARTICLES FOR THE NON-VIRAL DELIVERY OF PLASMID DNA FOR GENE EDITING AND RETINAL GENE THERAPY
    Publication number: 20230002790
    Abstract: Biodegradable particles for delivering a nucleic acid encoding gene-editing factors or a nucleic acid associated with a therapeutic protein to a cell, and compositions, methods, systems, and kits for gene editing in vivo or ex vivo or gene therapy for treating retinal eye diseases are disclosed.
    Type: Application
    Filed: October 10, 2019
    Publication date: January 5, 2023
    Inventors: Jordan J. Green, David Wilson, Yuan Rui, Donald J. Zack, Srinivasa Rao Sripathi, Cynthia A. Berlinicke
  • Compositions and methods for treatment of neurodegenerative disease
    Patent number: 9655882
    Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: May 23, 2017
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Donald J. Zack, Zhiyong Yang, Cynthia Berlinicke, Harry Quigley
  • Compositions and methods for treatment of neurodegenerative disease
    Patent number: 9539239
    Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: January 10, 2017
    Inventors: Donald Jeffrey Zack, Thomas Bannister, Tomas Vojkovsky, Zhiyong Yang, Cynthia Berlinicke
  • COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASE
    Publication number: 20160367527
    Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
    Type: Application
    Filed: October 19, 2015
    Publication date: December 22, 2016
    Applicants: THE SCRIPPS RESEARCH INSTITUTE, THE JOHNS HOPKINS UNIVERSITY
    Inventors: DONALD J. ZACK, THOMAS BANNISTER, TOMAS VOJKOVSKY, ZHIYONG YANG, CYNTHIA BERLINICKE
  • Compounds and methods of use thereof for treating neurodegenerative disorders
    Patent number: 9382229
    Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: July 5, 2016
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Donald J. Zack, Cynthia Berlinicke, Laszlo Hackler, Zhiyong Yang, Joseph P. Steiner, Tomas Vojkovsky, Dana Ferraris, Barbara S. Slusher, James Inglese
  • Compositions and methods for treatment of neurodegenerative disease
    Patent number: 9162981
    Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: October 20, 2015
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Donald J. Zack, Thomas Bannister, Tomas Vojkovsky, Zhiyong Yang, Cynthia Berlinicke
  • COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASE
    Publication number: 20150258061
    Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
    Type: Application
    Filed: February 19, 2015
    Publication date: September 17, 2015
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: DONALD J. ZACK, ZHIYONG YANG, CYNTHIA BERLINICKE, HARRY QUIGLEY
  • Compositions and methods for treatment of neurodegenerative disease
    Patent number: 8993615
    Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
    Type: Grant
    Filed: August 8, 2009
    Date of Patent: March 31, 2015
    Assignee: The Johns Hopkins University
    Inventors: Donald J. Zack, Zhiyong Yang, Cynthia Berlinicke, Harry Quigley
  • COMPOUNDS AND METHODS OF USE THEREOF FOR TREATING NEURODEGENERATIVE DISORDERS
    Publication number: 20140187540
    Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
    Type: Application
    Filed: February 15, 2012
    Publication date: July 3, 2014
    Applicant: The Johns Hopkins University
    Inventors: Donald J. Zack, Cynthia Berlinicke, Laszlo Hackler, Zhiyong Yang, Joseph P. Steiner, Tomas Vojkovsky, Dana Ferraris, Barbara S. Slusher, James Inglese
  • Compositions and Methods for Treatment of Neurodegenerative Disease
    Publication number: 20130217679
    Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
    Type: Application
    Filed: March 23, 2011
    Publication date: August 22, 2013
    Applicants: THE SCRIPPS RESEARCH INSTITUTE, THE JOHNS HOPKINS UNIVERSITY
    Inventors: Donald J. Zack, Thomas Bannister, Tomas Vojkovsky, Zhiyong Yang, Cynthia Berlinicke
  • COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASE
    Publication number: 20110172206
    Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
    Type: Application
    Filed: August 8, 2009
    Publication date: July 14, 2011
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Donald Jeffrey Zack, Zhiyong Yang, Cynthia Berlinicke, Harry Quigley