Patents by Inventor Cynthia L. Nichols

Cynthia L. Nichols has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
    Patent number: 4801712
    Abstract: D-2-Alkyl(or phenyl)thio-6-n-alkylergolines or .+-.-2-alkyl(or phenyl)thio-4-dialkylaminotetrahydrobenz[c,d]indoles, dopamine D-1 antagonists.
    Type: Grant
    Filed: June 11, 1987
    Date of Patent: January 31, 1989
    Assignee: Eli Lilly and Company
    Inventors: Bennett C. Laguzza, Cynthia L. Nichols, Nicholas J. Bach
  • Hydrazone immunoglobulin conjugates
    Patent number: 4801688
    Abstract: Immunoglobulin conjugates formed by reaction of an antineoplastic indole-dihydroindole vinca alkaloid containing a hydrazine group attached at C-3 or C-4 with an oxidized glycoprotein containing aldehyde groups.
    Type: Grant
    Filed: October 7, 1987
    Date of Patent: January 31, 1989
    Assignee: Eli Lilly and Company
    Inventors: Bennett C. Laguzza, Cynthia L. Nichols
  • 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
    Patent number: 4683313
    Abstract: D-2-Alkyl(or phenyl)thio-6-n-alkylergolines or .+-.-2-alkyl(or phenyl)thio-4-dialkylaminotetrahydrobenz[c,d]indoles, dopamine D-1 antagonists.
    Type: Grant
    Filed: June 24, 1985
    Date of Patent: July 28, 1987
    Assignee: Eli Lilly and Company
    Inventors: Bennett C. Laguzza, Cynthia L. Nichols, Nicholas J. Bach
  • Use of pyrimido[4,5-g]quinolines in treating parkinsonism
    Patent number: 4599339
    Abstract: Trans-(.+-.)-2-Amino or substituted amino-4-permissibly-substituted 6-lower alkyl or allyl-5,5a,-6,7,8,9,9a,10-octahydropyrimido[4,5-g]quinolines, the corresponding trans-(-)-stereoisomers and salts thereof, useful in treating anxiety, Parkinson's Syndrome, sexual dysfunction, depression, hypertension and elevated prolactin levels, and intermediates useful for the synthesis thereof.
    Type: Grant
    Filed: November 1, 1984
    Date of Patent: July 8, 1986
    Assignee: Eli Lilly and Company
    Inventors: Cynthia L. Nichols, Edmund C. Kornfeld
  • 2-Mercaptopyrimidohexahydroquinolines and related compounds
    Patent number: 4507478
    Abstract: Trans-(.+-.) or trans-(-)-2,4-permissibly-substituted-6-alkyl or allyl octahydropyrimido[4,5-g]quinolines and related compounds, ultraviolet light absorbers.
    Type: Grant
    Filed: September 26, 1983
    Date of Patent: March 26, 1985
    Assignee: Eli Lilly and Company
    Inventors: Cynthia L. Nichols, Edmund C. Kornfeld, John M. Schaus
  • Trans-( .+-.)-2,4,6-substituted-5,5a,6,7,8,9,9a,10-octahydro-pyrimido[4,5-g]quino lines
    Patent number: 4501890
    Abstract: Trans-(.+-.)-2-Amino or substituted amino-4-permissibly-substituted 6-lower alkyl or allyl-5,5a,-6,7,8,9,9a,10-octahydropyrimido[4,5-g]quinolines, the corresponding trans-(-)-stereoisomers and salts thereof, useful in treating anxiety, Parkinson's Syndrome, sexual dysfunction, depression, hypertension and elevated prolactin levels, and intermediates useful for the synthesis thereof.
    Type: Grant
    Filed: September 26, 1983
    Date of Patent: February 26, 1985
    Assignee: Eli Lilly and Company
    Inventors: Cynthia L. Nichols, Edmund C. Kornfeld