Patents by Inventor Cynthia M. Shafer

Cynthia M. Shafer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic derivatives of quinolinone benimidazoles
    Patent number: 6756383
    Abstract: Organi c compounds having the structural formulas I, II, and III are provided where the variables have the values described herein and R1 and R2 in structure I join together to form a 5 to 7 membered substituted or unsubstituted ring including at least one O, N, or S atom, and Z is an O, S, NH or NR group in structures I and II. Pharmaceutical formulations include the organic compound or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. A method of treating a patient includes administering a pharmaceutical formulation according to the invention to a patient in need thereof.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: June 29, 2004
    Assignee: Chiron Corporation
    Inventors: Paul A. Renhowe, Timothy D. Machajewski, Cynthia M. Shafer, Mary Ellen Wernette Hammond, Sabina Pecchi
  • Quinolinone derivatives
    Publication number: 20040097545
    Abstract: Organic compounds having the formulas I and II are provided where the variables have the values described herein.
    Type: Application
    Filed: July 3, 2003
    Publication date: May 20, 2004
    Inventors: Paul A. Renhowe, Sabina Pecchi, Timothy D. Machajewski, Cynthia M. Shafer, Clarke Taylor, William R. McCrea, Christopher McBride, Elisa Jazan
  • Benzimidazole quinolinones and uses thereof
    Publication number: 20040092535
    Abstract: Methods of inhibiting various enzymes and treating various conditions are provided that include administering to a subject a compound of Structure I or IB, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of the tautomer. Compounds having the Structure I and IB have the following structures and have the variables described herein. Such compounds may be used to prepare medicaments for use in inhibiting various enzymes and for use in treating conditions mediated by such enzymes.
    Type: Application
    Filed: August 19, 2003
    Publication date: May 13, 2004
    Applicant: Chiron Corporation
    Inventors: Paul A. Barsanti, Dirksen Bussiere, Stephen D. Harrison, Carla C. Heise, Johanna M. Jansen, Elisa Jazan, Timothy D. Michajewski, Christopher McBride, William R. McCrea, Simon Ng, Zhi-Jie Ni, Sabina Pecchi, Keith B. Pfister, Savithri Ramurthy, Paul A. Renhowe, Cynthia M. Shafer, Joel B. Silver, Allan S. Wagman, Marion Wiesmann
  • Quinolinone derivatives
    Publication number: 20040006101
    Abstract: Organic compounds having the formulas I and II are provided where the variables have the values described herein.
    Type: Application
    Filed: March 12, 2003
    Publication date: January 8, 2004
    Applicant: CHIRON CORPORATION
    Inventors: Paul A. Renhowe, Sabina Pecchi, Timothy D. Machajewski, Cynthia M. Shafer, Clarke Taylor, William R. McCrea, Christopher McBride, Eliza Jazan
  • Heterocyclic compounds
    Publication number: 20040002518
    Abstract: Organic compounds having the structural formulas I, II, and III are provided where the variables have the values described herein and R1 and R2 in structure I join together to form a 5 to 7 membered substituted or unsubstituted ring including at least one O, N, or S atom, and Z is an O, S, NH or NR group in structures I and II.
    Type: Application
    Filed: June 2, 2003
    Publication date: January 1, 2004
    Applicant: Chiron Corporation
    Inventors: Paul A. Renhowe, Cynthia M. Shafer
  • Indazole benzimidazole compounds
    Publication number: 20030207883
    Abstract: Organic compounds having the structure I are provided where the variables have the values described herein.
    Type: Application
    Filed: July 2, 2002
    Publication date: November 6, 2003
    Applicant: Chiron Corporation
    Inventors: Paul A. Renhowe, Cynthia M. Shafer, Christopher McBride, Joel Benjamin Silver, Sabina Pecchi, Timothy D. Machajewski, William R. McCrea, Daniel J. Poon, Teresa Thomas
  • Quinolinone derivatives
    Publication number: 20030158224
    Abstract: Organic compounds having the formulas I and II are provided where the variables have the values described herein.
    Type: Application
    Filed: October 30, 2002
    Publication date: August 21, 2003
    Applicant: Chiron Corporation
    Inventors: Paul A. Renhowe, Sabina Pecchi, Timothy D. Machajewski, Cynthia M. Shafer, Clarke Taylor, William R. McCrea Jr, Christopher McBride, Elisa Jazan
  • Quinolinone derivatives
    Patent number: 6605617
    Abstract: Organic compounds having the formulas I and II are provided where the variables have the values described herein. Pharmaceutical formulations include the organic compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and may be prepared by mixing the organic compounds or pharmaceutically acceptable salts of the organic compounds with a carrier and water. A method of treating a patient includes administering a pharmaceutical formulation according to the invention to a patient in need thereof.
    Type: Grant
    Filed: September 11, 2001
    Date of Patent: August 12, 2003
    Assignee: Chiron Corporation
    Inventors: Paul A. Renhowe, Sabina Pecchi, Timothy D. Machajewski, Cynthia M. Shafer, Clarke Taylor, William R. McCrea, Jr., Christopher McBride, Elisa Jazan
  • Quinolinone derivatives
    Publication number: 20030028018
    Abstract: Organic compounds having the formulas I and II are provided where the variables have the values described herein.
    Type: Application
    Filed: April 5, 2002
    Publication date: February 6, 2003
    Applicant: Chiron Coporation
    Inventors: Paul A. Renhowe, Sabina Pecchi, Timothy D Machajewski, Cynthia M. Shafer, Clarke Taylor, William R. McCrea, Christopher McBride, Elisa Jazan
  • Quinolinone derivatives
    Publication number: 20020107392
    Abstract: Organic compounds having the formulas I and II are provided where the variables have the values described herein.
    Type: Application
    Filed: September 11, 2001
    Publication date: August 8, 2002
    Inventors: Paul A. Renhowe, Sabina Pecchi, Timothy D. Machajewski, Cynthia M. Shafer, Clarke Taylor, William R. McCrea, Christopher McBride, Elisa Jazan
  • Heterocyclic compounds
    Publication number: 20020103230
    Abstract: Organic compounds having the structural formulas I, II, and III are provided where the variables have the values described herein and R1 and R2 in structure I join together to form a 5 to 7 membered substituted or unsubstituted ring including at least one O, N, or S atom, and Z is an O, S, NH or NR group in structures I and II.
    Type: Application
    Filed: August 30, 2001
    Publication date: August 1, 2002
    Inventors: Paul A. Renhowe, Timothy Machajewski, Cynthia M. Shafer, Mary Ellen Wernette-Hammond, Sabina Pecchi