Patents by Inventor Cynthia P. Paul

Cynthia P. Paul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTRACELLULAR EXPRESSION AND DELIVERY OF siRNAs IN MAMMALIAN CELLS
    Publication number: 20090042207
    Abstract: The present invention relates to compositions and methods for intracellular expression and delivery of siRNAs in mammalian cells. The siRNA is transcribed intracellularly as a double stranded RNA of about 18 to about 25 base pairs long from an expression cassette. Intracellular expression of siRNA is effective at reducing or eliminating expression of the targeted genes, and is applicable to reverse genetic analysis of genes and to genetic therapy, as for example to inhibiting expression of pathogenic genes and oncogenes.
    Type: Application
    Filed: August 21, 2008
    Publication date: February 12, 2009
    Inventors: David R. Engelke, Paul D. Good, Cynthia P. Paul
  • Intracellular expression and delivery of siRNAs in mammalian cells
    Publication number: 20030148519
    Abstract: The present invention relates to compositions and methods for intracellular expression and delivery of siRNAs in mammalian cells. The siRNA is transcribed intracellularly as a double stranded RNA of about 18 to about 25 base pairs long from an expression cassette. Intracellular expression of siRNA is effective at reducing or eliminating expression of the targeted genes, and is applicable to reverse genetic analysis of genes and to genetic therapy, as for example to inhibiting expression of pathogenic genes and oncogenes.
    Type: Application
    Filed: November 14, 2002
    Publication date: August 7, 2003
    Inventors: David R. Engelke, Paul D. Good, Cynthia P. Paul