Patents by Inventor Cynthia Rominger

Cynthia Rominger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay for B-Raf activity based on intrinsic MEK ATPase activity
    Publication number: 20060211073
    Abstract: The present invention provides a convenient assay to identify compounds with B-Raf inhibitory activity, referred to as the BRAMA (B-Raf Accelerated MEK ATPase) assay. The BRAMA assay is based on the discovery of ATPase activity of MEK, and utilizes changes in NADH concentration over time as an indicator of the production of ADP by activated MEK ATPase, where the MEK ATPase activity is activated by B-Raf. NADH concentration may conveniently be measured by Optical Density.
    Type: Application
    Filed: March 21, 2005
    Publication date: September 21, 2006
    Inventors: Earl May, Cynthia Rominger, Michael Schaber