Abstract: A tamper evident injection syringe of the disposable type is described having a container for storage of the material to be injected, means for expelling the material, an interference collar at one end of the container and a flange attached to the expelling means that is close fitting to the internal wall of the container and having a dimension greater than the interference collar such that the flange cannot pass through the interference means thereby preventing removal of the expelling means and the contents of the syringe. In addition a needle nub is described that permits connection of a needle or catheter and the connection of a tamper evident sealing cap that is easily removable yet when removed cannot be replaced without the removal being evident.