Abstract: The present invention provides methods and compositions for the evaluation, alteration and/or optimization of gene signaling. Methods and systems are also provided which exploit the information generated in the identification of new targets and non-canonical signaling pathways.

Abstract: The present invention provides methods and compositions for the treating a patient with a genetic disease, such as fibronectin glomerulopathy, hereditary coproporphyria and others. Methods and compositions are also provided for modulating the disease-associated gene(s) by altering gene signaling networks.

Abstract: A system that incorporates the subject disclosure may perform, for example, operations including obtaining a request from a mobile device to allow user access to restricted content of a separate device. The process further includes forwarding a token to the separate device by way of a second wireless network, to obtain a separate device token, and forwarding the token to the first device by way of the first network to obtain a mobile device token, wherein the mobile device token is forwarded to the separate device by way of a third network. A confirmation that the token was obtained at the separate device is based on the result of the comparison indicating a match between the mobile device token and the separate device token. Access to the restricted content of the separate device is authorized based on to the confirmation. Other embodiments are disclosed.

Abstract: A system that incorporates the subject disclosure may perform, for example, operations including obtaining a request from a mobile device to allow user access to restricted content of a separate device. The process further includes forwarding a token to the separate device by way of a second wireless network, to obtain a separate device token, and forwarding the token to the first device by way of the first network to obtain a mobile device token, wherein the mobile device token is forwarded to the separate device by way of a third network. A confirmation that the token was obtained at the separate device is based on the result of the comparison indicating a match between the mobile device token and the separate device token. Access to the restricted content of the separate device is authorized based on to the confirmation. Other embodiments are disclosed.

Abstract: A system that incorporates the subject disclosure may perform, for example, operations including receiving a request from a first device to access information content of a second device. The process further includes forwarding a token to the second device by way of a second wireless network, to obtain a second device token, and forwarding the token to the first device by way of the first network to obtain a first device token, wherein the first device forwards the first device token to the second device by way of a third network. A confirmation that the token was received at the first device is based on the result of the comparison indicating a match between the first device token and the second device token. Access to the information content of the second device is authorized in response to the confirmation. Other embodiments are disclosed.

Abstract: A system that incorporates teachings of the subject disclosure may include, for example, determining examination results based on sensory information obtained from sensors operating in a deployed environment, wherein the sensory information includes a combination of more than one of temperature, position, motion, and mission status. Software agents conduct reviews of examination results based on sensory ranges. Encryption key fragments are generated in response to the reviews of the examination results. The encryption key fragments are combined, to obtain a cryptographic session key. A clear-text version of encrypted sensitive information is obtained via the cryptographic session key responsive to the examination results falling within the sensory ranges. Decryption of the encrypted sensitive information is prevented responsive at least one of the examination results falling outside the sensory ranges. Other embodiments are disclosed.

Abstract: A system that incorporates teachings of the subject disclosure may include, for example, receiving multiple software agents and configuring a network of the multiple software agents according to a predetermined policy. The process can further include facilitating secure communications among software agents of the network of the multiple software agents according to the predetermined policy. A state of one of the system, a system environment within which the system operates, or a combination thereof can be determined, based on the secure communications among the software agents of the network of the multiple software agents. A computing environment can be facilitated conditionally on the state of the one of the system, the system environment, or the combination thereof, according to the predetermined policy to support a mission application. Other embodiments are disclosed.

Abstract: A system that incorporates the subject disclosure may perform, for example, operations including receiving a request from a first device to access information content of a second device. The process further includes forwarding a token to the second device by way of a second wireless network, to obtain a second device token, and forwarding the token to the first device by way of the first network to obtain a first device token, wherein the first device forwards the first device token to the second device by way of a third network. A confirmation that the token was received at the first device is based on the result of the comparison indicating a match between the first device token and the second device token. Access to the information content of the second device is authorized in response to the confirmation. Other embodiments are disclosed.

Abstract: A system that incorporates the subject disclosure may perform, for example, operations including receiving a request from a first device to access information content of a second device. The process further includes determining that the first device is authorized to access the information content according to authorization credentials, and determining a token associated with the request in response to determining that the first device is authorized to access the information content. The token is forwarded to the first device, and it is confirmed that the token was received at the first device. Access to the information content of the second device is authorized in response to confirming that the token was received at the first device. Other embodiments are disclosed.

Abstract: A system that incorporates the subject disclosure may perform, for example, operations including receiving a request from a first device to access information content of a second device. The process further includes determining that the first device is authorized to access the information content according to authorization credentials, and determining a token associated with the request in response to determining that the first device is authorized to access the information content. The token is forwarded to the first device, and it is confirmed that the token was received at the first device. Access to the information content of the second device is authorized in response to confirming that the token was received at the first device. Other embodiments are disclosed.

Abstract: A system that incorporates teachings of the subject disclosure may include, for example, receiving multiple software agents and configuring a network of the multiple software agents according to a predetermined policy. The process can further include facilitating secure communications among software agents of the network of the multiple software agents according to the predetermined policy. A state of one of the system, a system environment within which the system operates, or a combination thereof can be determined, based on the secure communications among the software agents of the network of the multiple software agents. A computing environment can be facilitated conditionally on the state of the one of the system, the system environment, or the combination thereof, according to the predetermined policy to support a mission application. Other embodiments are disclosed.

Abstract: A secure detection network system includes plurality of remote nodes, each remote node comprising a set of detector interfaces configured to couple to a set of detectors disposed to detect the presence of an illegal asset within a shipping container; at least one server node configured to initialize, install, and authenticate each remote node in the plurality of remote nodes, including delivering to each remote node an agent module, said agent module for each remote node comprising a node specific configuration file defining a set of nodes with which the remote node can communicate and a different encryption means corresponding to each node in the set of nodes; and a communication path coupling the plurality of remote nodes and the at least one server node.

Abstract: A secure detection network system includes plurality of remote nodes, each remote node comprising a set of detector interfaces configured to couple to a set of detectors disposed to detect the presence of an illegal asset within a shipping container; at least one server node configured to initialize, install, and authenticate each remote node in the plurality of remote nodes, including delivering to each remote node an agent module, said agent module for each remote node comprising a node specific configuration file defining a set of nodes with which the remote node can communicate and a different encryption means corresponding to each node in the set of nodes; and a communication path coupling the plurality of remote nodes and the at least one server node.

Abstract: A secure detection network system includes plurality of remote nodes, each remote node comprising a set of detector interfaces configured to couple to a set of detectors disposed to detect the presence of an illegal asset within a shipping container; at least one server node configured to initialize, install, and authenticate each remote node in the plurality of remote nodes, including delivering to each remote node an agent module, said agent module for each remote node comprising a node specific configuration file defining a set of nodes with which the remote node can communicate and a different encryption means corresponding to each node in the set of nodes; and a communication path coupling the plurality of remote nodes and the at least one server node.

Abstract: A secure detection network system includes plurality of remote nodes, each remote node comprising a set of detector interfaces configured to couple to a set of detectors disposed to detect the presence of an illegal asset within a shipping container; at least one server node configured to initialize, install, and authenticate each remote node in the plurality of remote nodes, including delivering to each remote node an agent module, said agent module for each remote node comprising a node specific configuration file defining a set of nodes with which the remote node can communicate and a different encryption means corresponding to each node in the set of nodes; and a communication path coupling the plurality of remote nodes and the at least one server node.

Abstract: The invention relates to a method of treating neuronal apoptosis in a mammal using nucleic acid encoding HSV-2 ICP10PK, or a polypeptide encoded thereby. The invention further relates to a method of treating neuronal apoptosis in a mammal using ICP10PK in combination with a nucleic acid encoding bcl-2, or the polypeptide encoded thereby. The invention also relates to the use of ICP10PK and ICP10PK in combination with bcl-2 to treat non-neuronal diseases characterized by apoptosis.

Abstract: A secure detection network system includes plurality of remote nodes, each remote node comprising a set of detector interfaces configured to couple to a set of detectors disposed to detect the presence of an illegal asset within a shipping container; at least one server node configured to initialize, install, and authenticate each remote node in the plurality of remote nodes, including delivering to each remote node an agent module, said agent module for each remote node comprising a node specific configuration file defining a set of nodes with which the remote node can communicate and a different encryption means corresponding to each node in the set of nodes; and a communication path coupling the plurality of remote nodes and the at least one server node.

Abstract: A secure detection network system includes plurality of remote nodes, each remote node comprising a set of detector interfaces configured to couple to a set of detectors disposed to detect the presence of an illegal asset within a shipping container; at least one server node configured to initialize, install, and authenticate each remote node in the plurality of remote nodes, including delivering to each remote node an agent module, said agent module for each remote node comprising a node specific configuration file defining a set of nodes with which the remote node can communicate and a different encryption means corresponding to each node in the set of nodes; and a communication path coupling the plurality of remote nodes and the at least one server node.

Abstract: The invention relates to a method of treating neuronal apoptosis in a mammal using nucleic acid encoding HSV-2 ICP10PK, or a polypeptide encoded thereby. The invention further relates to a method of treating neuronal apoptosis in a mammal using ICP10PK in combination with a nucleic acid encoding bcl-2, or the polypeptide encoded thereby. The invention also relates to the use of ICP10PK and ICP10PK in combination with bcl-2 to treat non-neuronal diseases characterized by apoptosis.

Abstract: In a printing system queuing jobs, some jobs are made dependent on primary jobs. If a user delete a primary job, the depending jobs are retrieved and automatically deleted.