Patents by Inventor Cynthia Stevenson

Cynthia Stevenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
    Publication number: 20050186143
    Abstract: The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 ?-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
    Type: Application
    Filed: November 17, 2004
    Publication date: August 25, 2005
    Applicant: Nektar Therapeutics
    Inventors: Cynthia Stevenson, Jayne Hastedt, S. Lehrman, Hi-Shi Chiang, David Bennett, David Lesikar, Bing Yang, David Gong, Kirsten Cabot
  • Modulating charge density to produce improvements in the characteristics of spray-dried proteins
    Publication number: 20050123509
    Abstract: Methods are provided for preparing spray-dried, drug-containing particles comprising the steps of selecting (i) a drug and an optional excipient, wherein the combination of the drug and optional excipient has an effective pI, and (ii) an aqueous solution having a pH that is different from the effective pI; (b) combining the solution and the drug and optional excipient, wherein an absolute net charge is associated with the drug and optional excipient as a result of an absolute difference between the pH and effective pI; and (c) spray drying the solution to form the spray-dried, drug-containing particles. Particles and compositions comprising the prepared particles as well as methods of use are also provided.
    Type: Application
    Filed: October 16, 2002
    Publication date: June 9, 2005
    Inventors: S. Lehrman, Bing Yang, Cynthia Stevenson
  • Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
    Patent number: 6838075
    Abstract: The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 ?-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: January 4, 2005
    Assignee: Nektar Therapeutics
    Inventors: Cynthia Stevenson, Jayne E. Hastedt, Russ Lehrman, Hi-Shi Chiang, David B. Bennett, David Lesikar, Bing Yang, David Gong, Kirsten Cabot
  • Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
    Publication number: 20030190291
    Abstract: The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 &agr;-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
    Type: Application
    Filed: March 14, 2003
    Publication date: October 9, 2003
    Applicant: Nektar Therapeutics
    Inventors: Cynthia Stevenson, Jayne E. Hastedt, S. Russ Lehrman, Hi-Shi Chiang, David B. Bennett, David Lesikar, Bing Yang, David Gong, Kirsten Cabot
  • Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
    Patent number: 6569406
    Abstract: The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 &agr;-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: May 27, 2003
    Assignee: Nektar Therapeutics
    Inventors: Cynthia Stevenson, Jayne E. Hastedt, S. Russ Lehrman, Hi-Shi Chiang, David B. Bennett, David Lesikar, Bing Yang, David Gong, Kirsten Cabot
  • Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
    Publication number: 20020065399
    Abstract: The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 &agr;-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
    Type: Application
    Filed: August 7, 2001
    Publication date: May 30, 2002
    Applicant: Inhale Therapeutic Systems, Inc.
    Inventors: Cynthia Stevenson, Jayne E. Hastedt, S. Russ Lehrman, Hi-Shi Chiang, David B. Bennett, David Lesikar, Bing Yang, David Gong, Kirsten Cabot