Patents by Inventor Cyril Dousson

Cyril Dousson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLIC PHOSPHATE SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF LIVER DISEASES
    Publication number: 20190365788
    Abstract: The present invention relates to Compounds of Formula (I) or Formula (II) or a pharmaceutically acceptable salt, solvate or enantiomer thereof, wherein A, B, R1, R2, R3, R4, Q and V are as defined herein. The present invention also relates to pharmaceutical compositions comprising a Compound of Formula (I) or Formula (II) and to their use in therapy.
    Type: Application
    Filed: November 15, 2017
    Publication date: December 5, 2019
    Applicant: IDENIX PHARMACEUTICALS LLC
    Inventors: Cyril Dousson, David Dukhan, Christophe C. Parsy, Stephane L. Bogen
  • NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF CANCER
    Publication number: 20170101431
    Abstract: Provided herein are compounds, compositions, and methods for the treatment of cancer, including leukemia. In one embodiment, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-cancer agents.
    Type: Application
    Filed: May 27, 2015
    Publication date: April 13, 2017
    Applicant: IDENIX PHARMACEUTICALS LLC
    Inventors: Cyril Dousson, David Dukhan, Christophe Claude Parsy, Francois-Rene Alexandre, Rachid Rahali, Jean-Laurent Paparin
  • Enantiomerically pure phosphoindoles as HIV inhibitors
    Patent number: 8486991
    Abstract: 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: July 16, 2013
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Richard Storer, Francois-Rene Alexandre, Cyril Dousson, Adel M. Moussa, Edward Bridges, Alistair Stewart, Jing Yang Wang, Benjamin Alexander Mayes
  • Phosphothiophene and phosphothiazole HCV polymerase inhibitors
    Patent number: 8193372
    Abstract: Provided herein are phosphothiophene and phosphothiazole compounds, for example, of any of Formulae I, IA, IIA, IIIA, IVA, VA, VIA, VIIA, IB, IIB, IIIB, IVB, VB, VIB and VIIB disclosed herein, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host infected with HCV.
    Type: Grant
    Filed: March 3, 2010
    Date of Patent: June 5, 2012
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Cyril Dousson, Claire Pierra, Jean-Francois Griffon, Frederic Leroy, Jean-Laurent Paparin, David Dukhan, Dominique Surleraux
  • Phospho-indoles as HIV inhibitors
    Patent number: 8044091
    Abstract: 3-phosphoindole compounds for the treatment of retroviral infections, and particularly for HIV, are described. Also included are compositions comprising the 3-phosphoindole derivatives alone or in combination with one or more other anti-retroviral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: October 25, 2011
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Richard Storer, Cyril Dousson, Francois-Rene Alexandre, Arlene Roland
  • ENANTIOMERICALLY PURE PHOSPHOINDOLES AS HIV INHIBITORS
    Publication number: 20110257129
    Abstract: 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Application
    Filed: June 2, 2011
    Publication date: October 20, 2011
    Inventors: Richard Storer, Francois-Rene Alexandre, Cyril Dousson, Adel M. Moussa, Edward Bridges, Alistair Stewart, Jing Yang Wang, Benjamin Alexander Mayes
  • Enantiomerically pure phosphoindoles as HIV inhibitors
    Patent number: 7960428
    Abstract: 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: June 14, 2011
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Richard Storer, Francois-Rene Alexandre, Cyril Dousson, Adel M. Moussa, Edward Bridges, Alistair Stewart, Jing Yang Wang, Benjamin Alexander Mayes
  • Phosphadiazine HCV polymerase inhibitors IV
    Patent number: 7932240
    Abstract: Provided herein are phosphadiazine polymerase inhibitor, for example, of any of Formulas IV, IV?, I?, II?, or IVa, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: April 26, 2011
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Cyril Dousson, Dominique Surleraux, Jean-Laurent Paparin, Claire Pierra, Arlène Roland
  • PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE HCV POLYMERASE INHIBITORS
    Publication number: 20100233123
    Abstract: Provided herein are phosphothiophene and phosphothiazole compounds, for example, of any of Formulae I, IA, IIA, IIIA, IVA, VA, VIA, VIIA, IB, IIB, IIIB, IVB, VB, VIIB and VIIB disclosed herein, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host infected with HCV.
    Type: Application
    Filed: March 3, 2010
    Publication date: September 16, 2010
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Cyril Dousson, Claire Pierra, Jean-Francois Griffon, Frederic Leroy, Jean-Laurent Paparin, David Dukhan, Dominique Surleraux
  • PHOSPHO-INDOLES AS HIV INHIBITORS
    Publication number: 20090163444
    Abstract: 3-phosphoindole compounds for the treatment of retroviral infections, and particularly for HIV, are described. Also included are compositions comprising the 3-phosphoindole derivatives alone or in combination with one or more other anti-retroviral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Application
    Filed: November 21, 2008
    Publication date: June 25, 2009
    Inventors: Richard Storer, Cyril Dousson, Francois-Rene Alexandre, Arlene Roland
  • Phospho-indoles as HIV inhibitors
    Patent number: 7534809
    Abstract: 3-phosphoindole compounds for the treatment of retroviral infections, and particularly for HIV, are described. Also included are compositions comprising the 3-phosphoindole derivatives alone or in combination with one or more other anti-retroviral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: May 19, 2009
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Richard Storer, Cyril Dousson, Francois-Rene Alexandre, Arlene Roland
  • PHOSPHADIAZINE HCV POLYMERASE INHIBITORS IV
    Publication number: 20090081158
    Abstract: Provided herein are phosphadiazine polymerase inhibitor, for example, of any of Formulas IV, IV?, I?, II?, or IVa, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: August 27, 2008
    Publication date: March 26, 2009
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Cyril Dousson, Dominique Surleraux, Jean-Laurent Paparin, Claire Pierra, Arlene Roland
  • PHOSPHADIAZINE HCV POLYMERASE INHIBITORS III AND VI
    Publication number: 20090060867
    Abstract: Provided herein are phosphadiazine polymerase inhibitor, for example, of Formula III, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: August 27, 2008
    Publication date: March 5, 2009
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Cyril Dousson, Dominique Surleraux, Jean-Francois Griffon, Claire Pierra, Arlene Roland, Rachid Rahali
  • PHOSPHADIAZINE HCV POLYMERASE INHIBITORS V
    Publication number: 20090060872
    Abstract: Provided herein are phosphadiazine polymerase inhibitor, for example, of any of Formulas V, V?, I?, II?, or Va, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: August 27, 2008
    Publication date: March 5, 2009
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Cyril Dousson, Dominique Surleraux, Jean-Laurent Paparin
  • PHOSPHADIAZINE HCV POLYMERASE INHIBITORS I AND II
    Publication number: 20090060866
    Abstract: Provided herein are phosphadiazine polymerase inhibitor, for example, of any of Formula I, II, III, I?, II?, I?, II?, Ia, IIa, or IIIa, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: August 27, 2008
    Publication date: March 5, 2009
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Cyril Dousson, Dominique Surleraux, Arlene Roland, Claire Pierra, Daniel Da Costa
  • Enantiomerically pure phosphoindoles as HIV inhibitors
    Publication number: 20080213217
    Abstract: 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Application
    Filed: September 28, 2007
    Publication date: September 4, 2008
    Inventors: Richard Storer, Francois-Rene Alexandre, Cyril Dousson, Adel M. Moussa, Edward Bridges, Alistair Stewart, Jing Yang Wang, Benjamin Alexander Mayes
  • Phospho-indoles as HIV inhibitors
    Publication number: 20060074054
    Abstract: 3-phosphoindole compounds for the treatment of retroviral infections, and particularly for HIV, are described. Also included are compositions comprising the 3-phosphoindole derivatives alone or in combination with one or more other anti-retroviral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Application
    Filed: September 16, 2005
    Publication date: April 6, 2006
    Inventors: Richard Storer, Cyril Dousson, Francois-Rene Alexandre, Arlene Roland