Patents by Inventor Cyril Lorenzato

Cyril Lorenzato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Specific binding molecule directed against galectin-3 protein
    Patent number: 11091552
    Abstract: A specific binding molecule is provided which binds to galectin-3 protein, methods of their production and methods of use.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: August 17, 2021
    Assignees: LABORATOIRE FRANAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUX
    Inventors: Alexandre Fontayne, Philippe Mondon, Jeanny Laroche-Traineau, Marie-Josée Jacobin-Valat, Martine Cérutti, Gisèle Clofent-Sanchez, Cyril Lorenzato, Audrey Hémadou
  • A SPECIFIC BINDING MOLECULE DIRECTED AGAINST GALECTIN-3 PROTEIN
    Publication number: 20210079101
    Abstract: A specific binding molecule is provided which binds to galectin-3 protein, methods of their production and methods of use.
    Type: Application
    Filed: October 5, 2018
    Publication date: March 18, 2021
    Inventors: Alexandre FONTAYNE, Philippe MONDON, Jeanny LAROCHE-TRAINEAU, Marie-Josée JACOBIN-VALAT, Martine CÉRUTTI, Gisèle CLOFENT-SANCHEZ, Cyril LORENZATO, Audrey HÉMADOU
  • Method of monitoring the release from liposomes of a product of interest using superparamagnetic nanoparticles
    Patent number: 10064962
    Abstract: The invention pertains to a method of monitoring the membrane permeabilization of a liposome and the incidental release of a compound of interest. The method utilizes liposomes comprising a thermosensitive lipidic membrane encapsulating the product of interest and superparamagnetic nanoparticles having the electrostatic surface charge below ?20 mV or above +20 mV when measured in an aqueous medium at physiological pH. In one embodiment, the method comprises the steps of: a) measuring relaxation time (T2*); b) heating the liposome at Tm or above Tm; c) measuring T2* after step b); d) obtaining the transverse relaxivity (r2*) values from the T2* values obtained from step a) and step c); and e) determining the ratio of r2* before and after the heating step b). A ratio above 1.5 indicates the liposome membrane permeabilization and the incidental release of the product of interest.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: September 4, 2018
    Assignees: NANOBIOTIX, UNIVERSITE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Agnés Pottier, Laurent Levy, Marie-Edith Meyre, Matthieu Germain, Cyril Lorenzato, Chrit Moonen, Pierre Smirnov
  • METHOD OF MONITORING THE RELEASE FROM LIPOSOMES OF A PRODUCT OF INTEREST USING SUPERPARAMAGNETIC NANOPARTICLES
    Publication number: 20160038616
    Abstract: The present application relates to a method of monitoring the membrane permeabilization of liposome and the incidental release of a compound of interest.
    Type: Application
    Filed: October 19, 2015
    Publication date: February 11, 2016
    Inventors: AGNÈS POTTIER, LAURENT LEVY, MARIE-EDITH MEYRE, MATTHIEU GERMAIN, CYRIL LORENZATO, CHRIT MOONEN, PIERRE SMIRNOV
  • METHOD OF MONITORING THE RELEASE FROM LIPOSOMES OF A PRODUCT OF INTEREST USING SUPERPARAMAGNETIC NANOPARTICLES
    Publication number: 20140227343
    Abstract: The present application relates to a method of monitoring the membrane permeabilization of liposome and the incidental release of a compound of interest.
    Type: Application
    Filed: January 31, 2012
    Publication date: August 14, 2014
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, NANOBIOTIX
    Inventors: Agnès Pottier, Laurent Levy, Marie-Edith Meyre, Matthieu Germain, Cyril Lorenzato, Chrit Moonen