Abstract: The present invention relates to platinum (IV) prodrug lipid-based amphiphiles and compositions thereof. In particular, it relates to cisplatin, oxaliplatin and carboplatin prodrugs with the capacity to make stable liquid crystalline nanoparticles and crystalline nanoparticles, and uses thereof to treat cancer in animals, including humans.

Abstract: The present invention relates to improved prodrugs, and compositions thereof. In particular, it relates to amphiphilic gemcitabine prodrugs or amphiphilic prodrugs of other biologically active molecules with the capacity to make liquid crystalline nanostructured nanoparticles, and uses thereof to treat animals, including humans.

Abstract: A system for introducing a fine bore catheter into a vein includes a cannula unit comprising an elongate tubular sheath, defining a distal end and a proximal end, and a hub enclosing the proximal end of the sheath. The cannula unit is adapted to receive an introducing needle for introducing the distal end of the sheath of the cannula into a vein. The system also includes a catheter unit, having a distal end and a proximal end, a body portion located at the proximal end of the catheter unit, and a catheter tube extending from the body portion to the distal end of the catheter unit.

Abstract: A fluxgate magnetometer includes a body of magnetic material, a drive coil and a sensing coil. At least one of the drive coil and the sensing coil is composed of two portions, each of the two portions being disposed in generally parallel planes which are spaced apart and respectively include an electrically insulating substrate and a spiral shaped portion which is electrically conductive supported by the electrically insulating substrate, the two portions being electrically connected such that electric current flows in the respective spiral shaped portions in opposite rotational senses relative to the body of magnetic material.

Abstract: An impact fuze arrangement for a missile in which an electromagnetic field is set up within a compartment in the body of the missile and a warhead detonating signal is generated if the field intensity varies by more than a predetermined amount, as will happen due to distortion of the compartment on impact of the missile on a target. Fields may be set up within a plurality of compartments and warhead detonation may be made conditional on distortion of more than one of these compartments.