Abstract: Methods and apparatus are provided for washing pipette tips, including the inside and outside of the pipette tip. Pipette wash devices comprise a main body comprising a wash chamber, a liquid channel, a gas channel, and a nozzle cavity, and a nozzle for providing a washing mist is positioned in the nozzle cavity and fluidically connected with the liquid channel and the gas channel. Methods of washing a pipette tip include inserting a pipette tip in a wash chamber; spraying a mist on an outside surface of the pipette tip; and blowing pressurized air or inert gas on the outside surface of the pipette tip, thereby washing and drying the pipette. Methods of washing a pipette tip also include passing one or more series of liquid slugs separated by gaseous gaps through the inside of the pipette tip.