Patents by Inventor D. Branch Moody

D. Branch Moody has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOSITIONS AND METHODS FOR TREHALOSE PHOSPHOLIPIDS
    Publication number: 20220119438
    Abstract: Provided herein are compositions of trehalose phospholipids and uses thereof, e.g., compounds and compositions comprising 6,6?-diphosphatidyltrehalose (diPT) and analogs thereof with modifications of the diPT chemical scaffold, that bind and agonize Mincle, and the use thereof as adjuvants.
    Type: Application
    Filed: January 8, 2020
    Publication date: April 21, 2022
    Inventors: Ildiko Van Rhijn, Adriaan J. Minnaard, D. Branch Moody, Tan-Yun Cheng, Jeffrey Buter
  • Methods and compositions for immunomodulation
    Patent number: 7795242
    Abstract: Novel antigens are provided herein. The antigens are associated with recognition of CD1 molecules by T cells. These antigens can be used as antigens, adjuvants or as immunomodulatory agents in a variety of therapeutic and prophylactic applications.
    Type: Grant
    Filed: October 15, 2004
    Date of Patent: September 14, 2010
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Ildiko Van Rhijn, David C. Young, D. Branch Moody
  • METHODS AND COMPOSITIONS FOR IMMUNOMODULATION
    Publication number: 20080226587
    Abstract: Compositions for immunomodulation that include acylated peptide antigens recognized by CD1c-restricted T cells, and methods of using the compositions, are provided herein.
    Type: Application
    Filed: October 2, 2007
    Publication date: September 18, 2008
    Inventors: D. Branch Moody, Ildiko Van Rhijn, David C. Young, Catherine E. Costello
  • Methods and compositions for immunomodulation using CD1 antigens
    Patent number: 7253159
    Abstract: The invention relates to novel CD1a-presented antigens. These antigens can be used as antigens, adjuvants or as immunomodulatory agents in a variety of diagnostic, therapeutic and prophylactic applications.
    Type: Grant
    Filed: April 19, 2004
    Date of Patent: August 7, 2007
    Assignees: The Brigham and Women's Hospital, Inc., Trustees of Boston University
    Inventors: D. Branch Moody, David C. Young, Catherine E. Costello
  • Methods and compositions for immunomodulation using CD1 antigens
    Publication number: 20040265976
    Abstract: The invention relates to novel CD1a-presented antigens. These antigens can be used as antigens, adjuvants or as immunomodulatory agents in a variety of diagnostic, therapeutic and prophylactic applications.
    Type: Application
    Filed: April 19, 2004
    Publication date: December 30, 2004
    Applicants: The Brigham and Women's Hospital, Inc., Trustees of Boston University
    Inventors: D. Branch Moody, David C. Young, Catherine E. Costello
  • Synthetic antigens for CD1-restricted immune responses
    Publication number: 20030206914
    Abstract: Synthetic antigens which comprise hydrophobic and hydrophilic components are provided for inducing CD1-restricted T cell responses in mammals. Further provided are methods for using these antigens and compositions which are combinations of CD1-recognized synthetic antigens, additional antigens, adjuvants and other substances that induce immune responses.
    Type: Application
    Filed: May 15, 2003
    Publication date: November 6, 2003
    Applicant: The Brigham and Women's Hospital, Inc.
    Inventors: Steven A. Porcelli, D. Branch Moody