Patents by Inventor D. Carleton Gajdusek

D. Carleton Gajdusek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CDNA clone encoding brain amyloid of alzheimer's disease
    Patent number: 4912206
    Abstract: Four clones have been isolated from an adult human brain cDNA library using an oligonucleotide probe corresponding to the first 20 amino acids of the brain amyloid polypeptide of the Alzheimer's disease. The open reading frame of the sequenced clone coded for 97 amino acids including the known amino acid sequence of this polypeptide. The 3.5 kb messenger RNA has been detected in mammalian brains and human thymus. The gene is highly conserved in evolution and been mapped to human chromosome 21.
    Type: Grant
    Filed: February 26, 1987
    Date of Patent: March 27, 1990
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Dmitry Y. Goldgaber, Michael Lerman, D. Carleton Gajdusek
  • Method for distinguishing Creutzfeldt-Jakob disease from other dementias
    Patent number: 4892814
    Abstract: A method for distinguishing Creutzfeldt-Jakob disease from other causes of human dementia by analyzing the cerebrospinal fluid of patients for proteins 130 and 131. The presence of these proteins indicates the presence of Creutzfeldt-Jakob disease.
    Type: Grant
    Filed: June 22, 1987
    Date of Patent: January 9, 1990
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Michael G. Harrington, Carl R. Merril, David M. Asher, D. Carleton Gajdusek