Abstract: A sphincter treatment apparatus includes an energy delivery device introduction member including a proximal end with a first radius of curvature and a distal end with a second radius of curvature. The introduction member is configured to be introduced into the sphincter in a non-deployed state and to be expanded to a deployed state to at least partially expand the sphincter or an adjoining structure. An energy delivery device is coupled to the introduction member. A retainer member is coupled to the energy delivery device introduction member and configured to controllably position the introduction member in an orifice of the sphincter.

Abstract: A trailer hitch receiver locking apparatus includes a main frame, a first pin assembly, a second pin assembly, a locking mechanism, and an automatically engaging safety mechanism. The first pin assembly and the second pin assembly are engaged in between the main frame and the locking mechanism in such way that the first pin assembly and the second pin assembly are operated in between a locked configuration and an unlocked configuration by the locking mechanism. The main frame is connected with the hitch receiver so that the trailer hitch receiver locking apparatus is able to secure different hitch devices with the hitch receiver through operation of the automatically engaging safety mechanism, the locking mechanism, the first pin assembly, and the second pin assembly.

Abstract: The present invention provides compounds of formula (I): (Formula (I); wherein A, R1, R2, R3I, V, X, and Z are defined herein, which are potassium channel inhibitors. The invention further provides pharmaceutical compositions comprising the compounds of formula (I) and their use in therapy, in particular in treatment of diseases or conditions that are mediated by Kir3.1 and/or Kir3.4 or any heteromultimers thereof, or that require inhibition of Kir3.1 and/or Kir3.4 or any heteromultimers thereof.

Abstract: A cable (2100) includes one or more conductor sets, one or more dielectric unitary blocks (2102) or reservoirs, first and second conductive shielding films (2108) disposed on opposite first and second sides of the conductor sets and the dielectric blocks (2102) or reservoirs, and an adhesive layer (2140). The shielding films (2108) include cover portions and pinched portions arranged such that, in cross-section, the cover portions of the shielding films in combination substantially surround each conductor set and each unitary block (2102) or reservoir, and the pinched portions of the shielding films in combination form pinched portions of the cable on each side of the conductor set and on at least one side of the unitary block (2102) or the reservoir. The adhesive layer (2140) bonds the first shielding film to the second shielding film in the pinched portions of the cable.

Abstract: A control module can include in at least one implementation an electronically actuated water control valve configured to shut off water flow through a water pipe, an electronic flow sensor configured to measure the flow of water through the water pipe, a temperature sensor configured to report water temperature, a water quality sensor, and a processing unit in communication with the electronically actuated water valve and the electronic flow sensor. The processing unit can be further configured to identify irregularities in the flow of the water through the water pipe, and in response to the identified irregularities, shut off the water flow through the water pipe.

Abstract: A shielded electrical ribbon cable includes conductor sets each including one or more insulated conductors, and a first and second shielding film on opposite sides of the cable. In transverse cross section, cover portions of the shielding films substantially surround each conductor set, and pinched portions of the films form pinched portions of the cable on each side of each conductor set. Dense packing is achieved while maintaining high frequency electrical isolation between conductor sets. When the cable is laid flat, a quantity S/Dmin is in a range from 1.7 to 2, where S is a center-to-center spacing between nearest insulated conductors of two adjacent conductor sets, and Dmin is the lesser of the outer dimensions of such nearest insulated conductors. Alternatively, a first and second conductor set each having only one pair of insulated conductors can satisfy a condition that ?/?1 is in a range from 2.5 to 3.

Abstract: Animation for the attachment of content items to a location on a content surface in a user interface is provided. A user interface showing a content surface may be displayed on a computer. The content surface may include a content item at an initial position above the content surface. The content surface may display content formatted for display over an area comprising a totality of the content surface. The computer may then receive in the user interface a request to attach the content item to a final position on the content surface. The computer may then display an animation of the content item moving, from the initial position, across the content surface until the final position has been reached. The computer may then attach the content item to the content surface at the final position.

Abstract: A semiconductor structure, method of manufacturing the same and design structure thereof are provided. The semiconductor structure includes a substrate including a semiconductor layer and a plurality of TSVs embedded therein. At least one TSV has a TSV tip extending from a backside surface of the substrate. The semiconductor structure further includes a multilayer metal contact structure positioned on the backside surface of the substrate. The multilayer metal contact structure includes at least a conductive layer covering the backside surface of the substrate and covering protruding surfaces of the TSV tip. The conductive layer has a non-planar first surface and a substantially planar second surface opposite of the first surface.

Abstract: A wafer probing system includes a probe card assembly having a plurality of individual probe structures configured make contact with a semiconductor wafer mounted on a motor driven wafer chuck, with each probe structure configured with a pressure sensing unit integrated therewith; and a controller configured to drive the probe card assembly with one or more piezoelectric driver units response to feedback from the pressure sensing units of the individual probe structures.

Abstract: A device for treating a tissue region at or near a lower esophageal sphincter to treat gastroesophageal reflux disease including a flexible tube having a plurality of arrays of first and second lumens, a proximal base, a distal hub, a plurality of radially spaced slits formed between the proximal base and distal hub, and a plurality of electrode ports and fluid ports, the electrode and fluid ports and the lumens are positioned between the slits. The tube is flexible outwardly between the slits to form an array of spines forming a three dimensional basket. A first electrode is movable within the first lumen of one array and a second electrode is movable within the first lumen of another array to exit through the electrode ports to penetrate tissue for application of energy to the tissue region to tighten the lower esophageal sphincter to treat gastroesophageal reflux disease.

Abstract: Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.

Abstract: The present invention relates to an agent having activity in the treatment of a tissue disruption.