Abstract: Devices are described relating to the retaining of surgical tools within the chuck of a reciprocating surgical instrument, such as a reciprocating saw. A securing chuck is disclosed for securing a surgical tool to a reciprocating surgical instrument that comprises a shaft and a securing member. The shaft defines an axis and has a cylindrical bore extending along the axis. The bore is shaped to receive a substantially rounded tool shank. A pair of transverse slots extends into the shaft along a plane passing through the axis for receiving a substantially flattened tool shank. The transverse slots intersect with the cylindrical bore. The securing member is carried by the shaft and is radially movable relative to the bore both inwardly and outwardly to secure the surgical tool in the chuck.

Abstract: The present invention relates to a process for the synthesis of conjugates of glycosaminoglycanes (GAG) with biologically active molecules of varying nature, comprising small molecules and macro-molecules. In particular, the present invention relates to the conjugation of hyaluronic acid (HA) and its derivatives with polypeptides and proteins with a biological action, such as, for example, interferons, erythropoietins, growth factors, insulin, cytokines, antibodies and hormones. An object of the present invention also relates to isolatable intermediates obtained by the partial or total reaction of GAG with protected amino aldehydes in the conjugation process mentioned above.

Abstract: Disclosed are hyaluronic acid derivatives functionalized with S-nitrosothiol groups of the general formula: wherein HA indicates hyaluronic acid and G indicates a suitable spacer.

Abstract: The invention relates to isolation of novel ?-actin and ribosomal protein S21 (rpS21) promoters and uses thereof. In particular, this invention features nucleotide sequences for rodent ?-actin promoters including, hamster, rat, and mouse, and hamster rpS21 promoter.

Abstract: Biomaterials obtainable by mixing the autocrosslinked derivative of hyaluronic acid (ACP) with the derivative (HBC) of hyaluronic acid crosslinked with 1,4-butanediol diglycidyl ether (BDDE) in the weight ratio of between 10:90 and 90:10 as novel fillers.

Abstract: The invention relates to isolation of novel ?-actin and ribosomal protein S21 (rpS21) promoters and uses thereof. In particular, this invention features nucleotide sequences for rodent ?-actin promoters including, hamster, rat, and mouse, and hamster rpS21 promoter.

Abstract: A cartridge includes a body, a reservoir, a filter, and a tab. The body is configured to be held in a fixed relationship relative to a stem, wherein the body comprises an inlet and an outlet. The inlet is configured to receive a fluid from a surgical instrument via the stem. The outlet is configured to output a first portion of the fluid from the cartridge. The reservoir is configured to receive the fluid from the inlet. The filter is configured to filter the first portion of the fluid as the first portion of the fluid is directed from the inlet, through the filter, and to the outlet. The tab connected to the body and configured to engage with the stem. The tab is configured to, when the cartridge is moved to disengage from the stem, at least one of break away from the body and become functionally inoperable.

Abstract: Provided herein are devices and methods for generating microfluidic gradients, including an array of unique microfluidic gradients within an array of microchannels. Fluids within conduits are mixed in an intersection region to generate a mixed flow stream in a source reservoir channel that provides a gradient that varies with axial distance from the intersection region. Microchannels having an inlet connected to the source reservoir channel are configured to provide a microfluidic gradient in the microchannel. An outlet end of the microchannel is connected to a sink reservoir channel. By varying the ratio of fluid flow rates from the fluid conduits, the microchannel gradients are tuned. In this manner, a large number of unique gradients or array of microfluidic gradients is provided, wherein the gradient can be any number of physical or chemical parameters, including concentrations and physical fluid properties.

Abstract: A method and a system for calibrating a camera in a surveillance system. The method and system use a mathematical rotation between a first coordinate system and a second coordinate system in order to calibrate a camera with a map of an area. In some embodiments, the calibration can be used to control the camera and/or to display a view cone on the map.

Abstract: Devices are described relating to the retaining of surgical tools within the chuck of a reciprocating surgical instrument, such as a reciprocating saw. A securing chuck is disclosed for securing a surgical tool to a reciprocating surgical instrument that comprises a shaft and a securing member. The shaft defines an axis and has a cylindrical bore extending along the axis. The bore is shaped to receive a substantially rounded tool shank. A pair of transverse slots extends into the shaft along a plane passing through the axis for receiving a substantially flattened tool shank. The transverse slots intersect with the cylindrical bore. The securing member is carried by the shaft and is radially movable relative to the bore both inwardly and outwardly to secure the surgical tool in the chuck.

Abstract: A cartridge includes a body, a reservoir, a filter, and a tab. The body is configured to be held in a fixed relationship relative to a stem, wherein the body comprises an inlet and an outlet. The inlet is configured to receive a fluid from a surgical instrument via the stem. The outlet is configured to output a first portion of the fluid from the cartridge. The reservoir is configured to receive the fluid from the inlet. The filter is configured to filter the first portion of the fluid as the first portion of the fluid is directed from the inlet, through the filter, and to the outlet. The tab connected to the body and configured to engage with the stem. The tab is configured to, when the cartridge is moved to disengage from the stem, at least one of break away from the body and become functionally inoperable.

Abstract: Devices are described relating to the retaining of surgical tools within the chuck of a reciprocating surgical instrument, such as a reciprocating saw. A securing chuck is disclosed for securing a surgical tool to a reciprocating surgical instrument that comprises a shaft and a securing member. The shaft defines an axis and has a cylindrical bore extending along the axis. The bore is shaped to receive a substantially rounded tool shank. A pair of transverse slots extends into the shaft along a plane passing through the axis for receiving a substantially flattened tool shank. The transverse slots intersect with the cylindrical bore. The securing member is carried by the shaft and is radially movable relative to the bore both inwardly and outwardly to secure the surgical tool in the chuck.

Abstract: A lubrication cartridge includes a cartridge body. A cartridge coupling is located on the cartridge body and defines a first passage and a second passage. A lubricant reservoir is housed in the cartridge body and comprises a pressurized fluid inlet coupled to the first passage and a lubricant outlet coupled to the second passage. A metering insert is located between the lubricant outlet and the second passage and comprises a density that controls lubricant flow between the lubricant reservoir and the second passage.

Abstract: A communication construct used for sharing podcast information associated with a podcast can include a link sent to a remote device (103) while playing the podcast, appended metadata to the link, and a communication packet enabling a user to transfer the link and the appended metadata while the user is playing the podcast. The link can be a universal record locator (URL) to the podcast and the appended metadata can include constructs having start times or end times for the podcast, bookmarks for portions of the podcast, digital rights management information, display description, podcast category, or relevant images. The appended metadata can also include URLs for mobile blogging, a sender's weblog, a video blog, a social contact site, contact information from a sender, or a vCard record. The communication constructs enable podcatcher software in a user's computer or remote device to automatically download the podcast associated with the link.

Abstract: A method and a system for calibrating a camera in a surveillance system. The method and system use a mathematical rotation between a first coordinate system and a second coordinate system in order to calibrate a camera with a map of an area. In some embodiments, the calibration can be used to control the camera and/or to display a view cone on the map.

Abstract: Biomaterials obtainable by mixing the autocrosslinked derivative of hyaluronic acid (ACP) with the derivative (HBC) of hyaluronic acid crosslinked with 1,4-butanediol diglycidyl ether (BDDE) in the weight ratio of between 10:90 and 90:10 as novel fillers.

Abstract: A method and a system for calibrating a camera in a surveillance system. The method and system use a mathematical rotation between a first coordinate system and a second coordinate system in order to calibrate a camera with a map of an area. In some embodiments, the calibration can be used to control the camera and/or to display a view cone on the map.

Abstract: A method and a system for calibrating a camera in a surveillance system. The method and system use a mathematical rotation between a first coordinate system and a second coordinate system in order to calibrate a camera with a map of an area. In some embodiments, the calibration can be used to control the camera and/or to display a view cone on the map.

Abstract: The object of the present invention relates to the new and surprising use of sulfated hyaluronic acid (HAS) as regulator agent of the cytokine activity (pro- and anti-inflammatory) and consequently the use of HAS for the preparation of a new medicine for topic use in the prevention and treatment of pathologies associated with the activation and/or deficiency of cytokines of a pro- and anti-inflammatory nature. The Applicant has in fact discovered the exclusive capacity of HAS in modulating the activity of these particular proteins, it has studied the action mechanism and demonstrated the substantial difference between the different sulfated types known in the state of the art, but above all it has demonstrated an unexpectedly high activity of HAS vs different types and strains of Herpes virus, Cytomegalovirus and the virus of vesicular stomatitis. Finally, a further object of the present invention is the use of HAS as a skin absorption promoter of drugs of an anti-inflammatory nature.

Abstract: The present invention relates to a process for the synthesis of conjugates of glycosaminoglycanes (GAG) with biologically active molecules of varying nature, comprising small molecules and macro-molecules. In particular, the present invention relates to the conjugation of hyaluronic acid (HA) and its derivatives with polypeptides and proteins with a biological action, such as, for example, interferons, erythropoietins, growth factors, insulin, cytokines, antibodies and hormones. An object of the present invention also relates to isolatable intermediates obtained by the partial or total reaction of GAG with protected amino aldehydes in the conjugation process mentioned above.