Patents by Inventor D. James Surmeier

D. James Surmeier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR MODULATING CALCIUM CHANNELS
    Publication number: 20210177819
    Abstract: The present invention relates to methods and compositions for modulating calcium channels. In particular, the present invention provides methods and compositions for modulating (e.g., disrupting) Cav1.3a calcium channels for research and therapeutic methods (e.g., treating dopaminergic diseases and conditions).
    Type: Application
    Filed: October 8, 2020
    Publication date: June 17, 2021
    Inventors: D. James Surmeier, Michelle Day, Jun Ding, C. Savio Chan, Jaime Guzman, Jeff Mercer, Tatiana Tkatch, Zhongfeng Wang, Ema Ilijic
  • METHODS AND COMPOSITIONS FOR MODULATING CALCIUM CHANNELS
    Publication number: 20180280371
    Abstract: The present invention relates to methods and compositions for modulating calcium channels. In particular, the present invention provides methods and compositions for modulating (e.g., disrupting) Cav1.3a calcium channels for research and therapeutic methods (e.g., treating dopaminergic diseases and conditions).
    Type: Application
    Filed: June 7, 2018
    Publication date: October 4, 2018
    Inventors: D. James Surmeier, Michelle Day, Jun Ding, C. Savio Chan, Jaime Guzman, Jeff Mercer, Tatiana Tkatch, Zhongfeng Wang, Ema Ilijic
  • METHODS AND COMPOSITIONS FOR MODULATING CALCIUM CHANNELS
    Publication number: 20180064697
    Abstract: The present invention relates to methods and compositions for modulating calcium channels. In particular, the present invention provides methods and compositions for modulating (e.g., disrupting) Cav1.3a calcium channels for research and therapeutic methods (e.g., treating dopaminergic diseases and conditions).
    Type: Application
    Filed: September 2, 2016
    Publication date: March 8, 2018
    Inventors: D. James Surmeier, Michelle Day, Jun Ding, C. Savio Chan, Jaime Guzman, Jeff Mercer, Tatiana Tkatch, Zhongfeng Wang, Ema Ilijic
  • METHODS AND COMPOSITIONS FOR MODULATING CALCIUM CHANNELS
    Publication number: 20130345230
    Abstract: The present invention relates to methods and compositions for modulating calcium channels. In particular, the present invention provides methods and compositions for modulating (e.g., disrupting) Cav1.3a calcium channels for research and therapeutic methods (e.g., treating dopaminergic diseases and conditions).
    Type: Application
    Filed: August 27, 2013
    Publication date: December 26, 2013
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: D. James Surmeier, Michelle Day, Jun Ding, Savio Chan, Jamie Guzman, Jeff Mercer, Tatiana Tkatch, Zhongfeng Wang, Ema Ilijic
  • METHODS AND COMPOSITIONS FOR MODULATING CALCIUM CHANNELS
    Publication number: 20120264808
    Abstract: The present invention relates to methods and compositions for modulating calcium channels. In particular, the present invention provides methods and compositions for modulating (e.g., disrupting) Cav1.3a calcium channels for research and therapeutic methods (e.g., treating dopaminergic diseases and conditions).
    Type: Application
    Filed: June 7, 2012
    Publication date: October 18, 2012
    Inventors: D. James Surmeier, Michelle Day, Jun Ding, Savio Chan, Jamie Guzman, Jeff Mercer, Tatiana Tkatch, Zhongfeng Wang, Ema Ilijic
  • MANIPULATION OF NEURONAL ION CHANNELS
    Publication number: 20100093834
    Abstract: The present invention provides compositions and methods for the manipulation of ion channels. For example, the present invention relates to Parkinson's and other neurological diseases and conditions, and treatments thereof. In particular, the present invention provides methods of decreasing pathophysiological high frequency neuronal bursts of Parkinson's and other neurological diseases and conditions. Methods of the present invention comprise decreasing Kv3 ion channel activity in fast-spiking neurons, including by decreasing activity of a Kv3.4 protein and by specifically targeting a Kv3.4 protein with an inhibitor.
    Type: Application
    Filed: December 1, 2009
    Publication date: April 15, 2010
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: D. James Surmeier, Tatiana Tkatch, Gytis Baranauskas
  • Manipulation of neuronal ion channels
    Patent number: 7629323
    Abstract: The present invention provides compositions and methods for the manipulation of ion channels. For example, the present invention relates to Parkinson's and other neurological diseases and conditions, and treatments thereof. In particular, the present invention provides methods of decreasing pathophysiological high frequency neuronal bursts of Parkinson's and other neurological diseases and conditions. Methods of the present invention comprise decreasing Kv3 ion channel activity in fast-spiking neurons, including by decreasing activity of a Kv3.4 protein and by specifically targeting a Kv3.4 protein with an inhibitor.
    Type: Grant
    Filed: January 21, 2004
    Date of Patent: December 8, 2009
    Assignee: Northwestern University
    Inventors: D. James Surmeier, Tatiana Tkatch, Gytis Baranauskas
  • METHODS AND COMPOSITIONS FOR MODULATING CALCIUM CHANNELS
    Publication number: 20090197920
    Abstract: The present invention relates to methods and compositions for modulating calcium channels. In particular, the present invention provides methods and compositions for modulating (e.g., disrupting) Cav1.3a calcium channels for research and therapeutic methods (e.g., treating dopaminergic diseases and conditions).
    Type: Application
    Filed: January 28, 2009
    Publication date: August 6, 2009
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: D. James Surmeier, Michelle Day, Jun Ding, Savio Chan, Jamie Guzman, Jeff Mercer, Tatiana Tkatch, Zhongfeng Wang, Ema Ilijic
  • Manipulation of neuronal ion channels
    Publication number: 20040220082
    Abstract: The present invention provides compositions and methods for the manipulation of ion channels. For example, the present invention relates to Parkinson's and other neurological diseases and conditions, and treatments thereof. In particular, the present invention provides methods of decreasing pathophysiological high frequency neuronal bursts of Parkinson's and other neurological diseases and conditions. Methods of the present invention comprise decreasing Kv3 ion channel activity in fast-spiking neurons, including by decreasing activity of a Kv3.4 protein and by specifically targeting a Kv3.4 protein with an inhibitor.
    Type: Application
    Filed: January 21, 2004
    Publication date: November 4, 2004
    Applicant: Northwestern University
    Inventors: D. James Surmeier, Tatiana Tkatch, Gytis Baranauskas