Abstract: A valve includes a body having a first end, a second end opposite the first end, and a throughbore extending from the first end to the second end along a central axis, a valve element positioned within the throughbore for selectably isolating fluid flow through the throughbore, a seal end cap including a flange and a neck, wherein the neck is inserted into the throughbore from the second end of the body to engage with the valve element, and a hub end cap including a mounting flange engaged with the flange of the seal end cap, wherein the flange of the seal end cap is engaged with the second end of the body whereby the flange of the seal end cap is compressed between the second end of the body and the mounting flange of seal end cap.

Abstract: A manufacturing method includes: in a loom, weaving a woven reinforcing fibre fabric including a plurality of reinforcing fibre tows and polymeric material; and heating the woven reinforcing fibre fabric as it exits the loom to cause the polymeric material to melt and/or cure.

Abstract: Provided herein are feedback controller circuits and cell state classifiers for tunable phosphorylation-based transcriptional regulation of gene expression in cells based on intracellular miRNA profiles and degradation by small molecules. Also provided are methods of using feedback controller circuits and cell state classifiers for determining the cell state, and methods of treating cells and subjects using feedback controller circuits and cell state classifiers encoding therapeutic output molecules.

Abstract: An apparatus for manufacturing an annular or semi-annular composite component having a circumferentially-extending base and a flange, the apparatus including: a loom for weaving a woven preform of fibre reinforcement material for the composite component; a rotatable mandrel configured to receive and draw the woven preform through the loom for weaving; and a guide disposed between the loom and the rotatable mandrel, configured so that a woven preform drawn by the rotatable mandrel along a guide path under tension engages the guide to transition to a flanged profile at a lip of the guide before being received on the mandrel.

Abstract: A prosthetic foot includes a spring component and a sole component. The spring component comprises two or more stacked beam elements, each beam element including, along the length of the respective beam element, a first portion and a second portion, and the second portion of the beam element includes an extent with a length-varying width. The respective beam elements are fixed to each other and to the sole component proximate the heel portion of the sole component or the toe portion of the sole component at the first portions of the respective beam elements to form a fixed end of a cantilevered composite beam. The second portions of the respective beam elements are laterally movable with respect to each other when the spring component deflects.

Abstract: Systems and methods are provided for fabricating a fuselage of an aircraft. The method includes: disposing arcuate sections of fuselage at a track of a factory such that concavities of the arcuate sections of the fuselage face a floor of the factory, and bearing edges of the arcuate sections of fuselage directly contact the track; advancing the arcuate sections of fuselage synchronously along the track in a process direction; and performing work within concavities of the arcuate sections of fuselage during pauses between pulses of the arcuate section of fuselage via stations that are disposed beneath the concavities and that are directly mounted to the floor of the factory.

Abstract: A sample purification system includes a mixing zone; a settling zone in fluid communication with the mixing zone; a mixer element disposed in the mixing zone, the mixer element being configured to mix immiscible liquids to form a mixture; and a first acoustic wave settler configured to emit an acoustic wave into the mixture.

Abstract: Certain embodiments of the present application relate to an adjustable ostomy wafer system including an ostomy wafer and an insert ring. The ostomy wafer includes an adjustable layer with an effluent opening through which effluent flows, and the adjustable layer has a body-facing side and a non-body-facing side. The insert ring is capable of providing or increasing convexity of the adjustable layer when the insert ring is pressed against the non-body-facing side of the adjustable layer.

Abstract: Various embodiments relate to sensing defects associated with a window. Furthermore, various embodiments relate to performing image processing to produce a corrected image of a scene based at least partly on data corresponding to the detected defects. In some examples, one or more lighting modules may be used to illuminate the window to facilitate detection of the defects by one or more sensor devices.

Abstract: Protective cover layers for electronic devices are described. In an embodiment, an electronic device includes a display panel and a protective cover layer over the display panel. The protective cover layer includes a transparent support substrate and a hardcoat layer covering an exterior facing surface of the transparent support substrate. The display panel may be a flexible display panel and the protective cover layer may flex with the flexible display panel.

Abstract: Systems and methods are provided for fabrication of frames for aircraft.

Abstract: An apparatus includes first and second elongate members having first and second stapling surfaces and being configured to releasably couple together. A clamp member is movable from a first position to a second position to approximate the stapling surfaces for clamping tissue. A latch member is transitionable from an unlatched state to a latched state to releasably retain the clamp member in the second position. A firing assembly is actuatable from a home position to fire staples into the clamped tissue. The latch member is transitionable from the unlatched state to the latched state when the clamp member is in the second position while the firing assembly is in the home position. The latch member is inhibited from transitioning from the unlatched state to the latched state when the clamp member is in the second position while the firing assembly is displaced from the home position.

Abstract: Among other things, aspects, features, and implementations of wireless mesh networks and wireless mesh network devices are described.

Abstract: Methods and systems are provided for electronically managing coupons. The user no longer has to clip and organize coupons. The need for hand processing of coupons is substantially reduced. Rebates or payments for coupons can be substantially hastened and can be deposited directly into a user's bank, credit card, or payment provider account. Merchants and manufactures no longer have to be concerned with receiving bad (e.g., invalid, expired, or counterfeit) coupons. Thus, the electronic coupon management system benefits the users, merchants, and manufactures.

Abstract: A method for collecting a sterilized fluid includes passing a fluid through an inlet stem and into a chamber of a storage container so that the fluid collects within the chamber of the storage container; and applying a beam of radiation to the inlet stem so that the beam of radiation passes through the inlet stem and through at least a portion of the fluid passing through the inlet stem, the beam of radiation at least partially sterilizing the fluid passing through the inlet stem and into the chamber of the storage container.

Abstract: Examples of the present disclosure describe systems and methods for maintaining stale files to minimize computing costs. In examples, a determination is made regarding whether a hydrated file is eligible to remain temporarily stale. If the hydrated file is determined to be eligible to remain temporarily stale, the hydrated file is caused to remain stale at a time when a content refresh for the hydrated file is pending. While the hydrated file remains stale, a set of rules for determining whether the hydrated file should be refreshed is evaluated. If, based on the set of rules, it is determined that the hydrated file should be refreshed, the hydrated file is refreshed.

Abstract: A ride-along vehicle may include both handles and foot rests each capable of providing power to the pump arm. An improved pumper arm and steering mechanism may include a pivot joint that is provided by rods, pins, or bolts attached to opposite sides of the pumper arm. The universal joint between the steering arm and the pumper arm can be aligned with the center of the pivot point to prevent rocking of the steering arm as the pumper arm is actuated.

Abstract: A hybrid rocket solid fuel grain having a cylindrical shape and defining a center port is additive manufactured from a compound of thermoplastic fuel and passivated nanocomposite aluminum additive. The fuel grain comprises a stack of fused layers, each layer formed as a plurality of fused abutting concentric circular beaded structures arrayed to define a center port. During operation, an oxidizer is introduced along the center port, with combustion occurring along the exposed port wall. Each circular beaded structure defines geometry that increases the surface area available for combustion. As each layer ablates the next abutting layer, exhibiting a similar geometry, is revealed, undergoes a gas phase change, and ablates. This process repeats and persists until oxidizer flow is terminated or the fuel grain material is exhausted. To safely achieve this construction, a fused deposition additive manufacturing apparatus, modified to shield the nanocomposite material from the atmosphere, is used.

Abstract: A hybrid rocket solid fuel grain having a cylindrical shape and defining a center port is additive manufactured from a compound of thermoplastic fuel and passivated nanocomposite aluminum additive. The fuel grain comprises a stack of fused layers, each layer formed as a plurality of fused abutting concentric circular beaded structures arrayed to define a center port. During operation, an oxidizer is introduced along the center port, with combustion occurring along the exposed port wall. Each circular beaded structure defines geometry that increases the surface area available for combustion. As each layer ablates the next abutting layer, exhibiting a similar geometry, is revealed, undergoes a gas phase change, and ablates. This process repeats and persists until oxidizer flow is terminated or the fuel grain material is exhausted. To safely achieve this construction, a fused deposition additive manufacturing apparatus, modified to shield the nanocomposite material from the atmosphere, is used.

Abstract: A cylindrically-shaped hybrid rocket engine solid fuel grain defines an axial combustion port. A fuel grain material comprises a compounded blend of thermoplastic fuel and aluminum. The fuel grain comprises fused stack layers, each layer comprising a plurality of fused abutting concentric beaded structures arrayed to define the combustion port; the port exhibits a rifling pattern or rifling inducing geometry along the port wall. When an oxidizer is introduced into the combustion port combustion occurs along the exposed port wall. Each beaded structure defines a geometry that increases the combustion surface area while inducing a vortex flow of oxidizer and fuel gas. As each layer ablates, an abutting layer exhibiting a similar geometry, is revealed, undergoes a gas phase change, and ablates. This process repeats and persists until oxidizer flow is terminated or the fuel grain material is exhausted. The fuel grain may be manufactured by an additive manufacturing process.