Patents by Inventor D. Prince

D. Prince has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystallization and structure determination of glycosylated human beta secretase, an enzyme implicated in alzheimer's disease
    Publication number: 20060136141
    Abstract: An inhibitor bound form of human beta secretase, also known as memapsin 2 and BACE, particularly in a glycosylated form as expressed in Chinese hamster ovary (CHO), HEK293 cells, or in insect cells as part of a Baculovirus expression system has been crystallized, and the three dimensional x-ray crystal structure has been solved to 3.2 ? resolution. The x-ray crystal structure is useful for solving the structure of other molecules or molecular complexes, and designing inhibitors of human beta secretase activity.
    Type: Application
    Filed: December 28, 2005
    Publication date: June 22, 2006
    Inventors: Timothy Benson, Jim Durbin, D. Prince