Patents by Inventor Dóra Méhn

Dóra Méhn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cholesterol loaded insect cell membranes as test proteins
    Patent number: 8129197
    Abstract: The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane.
    Type: Grant
    Filed: May 14, 2007
    Date of Patent: March 6, 2012
    Assignee: SOLVO Biotechnológial ZRT.
    Inventors: György Báthori, Dóra Méhn, Pál Ákos, Péter Krajcsi, Lajos Szente, Éva Fenyvesi, Ágnes Telbisz, Balázs Sarkadi, András Váradi, Szilvia Gedey, Hristos Glavinas, Emese Kis, Tünde Nagy, Attila Németh, Éva Molnár
  • CHOLESTEROL LOADED INSECT CELL MEMBRANES AS TEST SYSTEMS FOR ABC TRANSPORTER PROTEINS
    Publication number: 20100021927
    Abstract: The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane.
    Type: Application
    Filed: May 14, 2007
    Publication date: January 28, 2010
    Inventors: György Báthori, Dóra Méhn, Pál Ákos, Péter Krajcsi, Lajos Szente, Éva Fenyvesi, Ágnes Telbisz, Balázs Sarkadi, András Váradi, Szilvia Gedey, Hristos Glavinas, Emese Kis, Tünde Nagy, Attila Németh, Éva Molnár