Patents by Inventor D. Scott Snyder

D. Scott Snyder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the production of 3-O-deactivated-4?-monophosphoryl lipid A (3D-MLA)
    Patent number: 9512159
    Abstract: The invention relates to a method for extracting lipopolysaccharide (LPS) from rough trough mutant bacteria cells by extracting the cells with an aqueous aliphatic alcohol having from 1 to 4 carbon atoms at a temperature between 35 and 65 degrees C. to produce cells having a reduced phospholipid content. The resultant cells are then extracted with chloroform/methanol to yield LPS.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: December 6, 2016
    Assignee: CORIXA Corporation
    Inventors: Kent R. Myers, D. Scott Snyder
  • Methods for the Production of 3-O-Deactivated-4'-Monophosphoryl Lipid A (3D-MLA)
    Publication number: 20140243513
    Abstract: Herein is disclosed a method for producing lipopolysaccharide (LPS), comprising: (a) growing a culture of a deep rough mutant bacterial strain in a medium; (b) maintaining the culture in stationary phase for at least about 5 hr; (c) harvesting, cells from the culture; and (d) extracting LPS from the cells. The method allows for the production of an LPS which can be used to produce a 3-O-deacylated monophosphoryl lipid A (3D-MLA) having at least about 20 mol % of the hexaacyl congener group.
    Type: Application
    Filed: May 6, 2014
    Publication date: August 28, 2014
    Applicant: GlaxoSmithKline Biologicals S.A.
    Inventors: Kent R. MYERS, D. Scott SNYDER
  • Methods for the production of 3-O-deactivated-4'-monophosphoryl lipid a (3D-MLA)
    Publication number: 20030031684
    Abstract: Herein is disclosed a method for producing lipopolysaccharide (LPS), comprising: (a) growing a culture of a deep rough mutant bacterial strain in a medium; (b) maintaining the culture in stationary phase for at least about 5 hr; (c) harvesting cells from the culture; and (d) extracting LPS from the cells. The method allows for the production of an LPS which can be used to produce a 3-O-deacylated monophosphoryl lipid A (3D-MLA) having at least about 20 mol % of the hexaacyl congener group.
    Type: Application
    Filed: March 14, 2002
    Publication date: February 13, 2003
    Applicant: Corixa Corporation
    Inventors: Kent R. Myers, D. Scott Snyder