Patents by Inventor D. T. Philip Davies

D. T. Philip Davies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay for marker of human polymorphonuclear leukocyte elastase activity
    Patent number: 6124107
    Abstract: A immunoassay based on the detection of leukocyte-elastase produced fibrinogen cleavage peptides which allows the evaluation of the potency of compounds that inhibit formation of cleavage peptides in a variety of in vitro cell biological situations is provided. The assay may be employed to detect an endogenous leukocyte-elastase produced fibrinogen cleavage peptide signal in normal human plasma and at elevated levels in cystic fibrosis plasma and in rheumatoid arthritis synovial fluid samples. The assay procedure can be a single step assay which allows for the rapid and reproducible detection of specific cleavage peptides.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: September 26, 2000
    Assignee: Merck & Co., Inc.
    Inventors: John L. Humes, Richard Allen Mumford, D. T. Philip Davies, Mary Ellen Dahlgren, Joshua Schafer Boger