Patents by Inventor Dávid Simon

Dávid Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12378915
    Abstract: A fuel supply circuit of an aircraft engine includes a centrifugal pump mechanically coupled with an engine shaft delivering mechanical power. The circuit further includes at least one electromagnetic pump including at least one stator delimiting an annular internal volume in which is present a rotor able to drive a fluid, a plurality of magnets annularly distributed on the rotor and at least a plurality of coils annularly distributed inside the stator face-to-face with the magnets. The rotor is connected to the engine shaft by a one-way clutching element.
    Type: Grant
    Filed: May 6, 2024
    Date of Patent: August 5, 2025
    Assignee: SAFRAN HELICOPTER ENGINES
    Inventors: Franck Albert Robert Dupeu, Jean-Marie André Robert Gigon, David Simon Serge Taieb
  • Publication number: 20250236656
    Abstract: The present disclosure provides multimeric polypeptides comprising at least one G-coupled polypeptide receptor (GPCR) ligand for treatment of various conditions and diseases.
    Type: Application
    Filed: December 12, 2024
    Publication date: July 24, 2025
    Applicant: Amide Technologies
    Inventors: Patrick GLEASON, Ganesh JEDHE, Mark David SIMON, Bradley L. PENTELUTE
  • Patent number: 12325931
    Abstract: Disclosed herein are methods and devices that use a low-thermal conductivity inert gas to shield reactant gases and thus enabling a cold wall operation within a hot wall system.
    Type: Grant
    Filed: June 13, 2020
    Date of Patent: June 10, 2025
    Assignees: Alliance for Sustainable Energy, LLC, Rochester Institute of Technology
    Inventors: Elisabeth Lynne McClure, Kevin Louis Schulte, Aaron Joseph Ptak, John David Simon, Wondwosen Tilahun Metaferia
  • Patent number: 12320770
    Abstract: The invention provides a solid state reference electrode comprising: a reference element in ionic communication with a composite, the composite comprising a water-permeable polymeric matrix loaded with a solid inorganic salt comprising a reference anion; an electrode surface for contacting an analyte; and a solid ion-exchange material located between the electrode surface and the reference element, the solid ion-exchange material comprising one or more non-interfering ions, wherein in use the solid ionexchange material immobilises one or more interfering ions, when present in solution in the analyte, by exchange with the noninterfering ions.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: June 3, 2025
    Assignee: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: David Simon Macedo, Mikko Kalevi Vepsäläinen
  • Patent number: 12290783
    Abstract: Gaseous carbon compounds can be converted to carbon neutral or negative products using biological processes to metabolise the gaseous carbon compounds or use thermochemical processes to convert gaseous carbon compounds to syngas followed by thermochemical or biological processes to produce products. The gaseous carbon compounds include a mixture of CO2 and CH4 from either a single source, or two or more different sources. Separate biological processes are incorporated to process different gaseous carbon compounds. A gaseous carbon compound produced as a by-product of one biological process can be used as at least part of the feedstock for another process. A renewable energy system can be provided to power equipment. A control system can be used to control flow of gaseous carbon compounds and reactants entering the entire carbon processing systems to provide mass balanced quantities of gaseous carbon compounds and reactants in each processing system and/or between processing systems.
    Type: Grant
    Filed: July 7, 2023
    Date of Patent: May 6, 2025
    Assignee: Woodside Energy Technologies Pty Ltd
    Inventors: Jitendra Achyut Joshi, Min Ao, Michael Edward Lev Massen-Hane, Qiqing Shen, Sui Boon Liaw, Alexander David Simons
  • Patent number: 12269147
    Abstract: Disclosed is a latching mechanism for a high-torque tool that allows a top semicircular segment to be connected and disconnected from a bottom semicircular segment, which allows a hex jaw (reaction gear) to engage a fluid fitting static nut for application of high torques. A pivoted latch has a curved blade, which is mounted closer to the center point of the hex jaw (reaction gear) than the latch pivot pin of the pivoted latch so that all of the forces are absorbed by the curved blade rather than the latch pivot pin.
    Type: Grant
    Filed: July 14, 2021
    Date of Patent: April 8, 2025
    Inventors: David Wilson, Jr., David Simone Wilson
  • Publication number: 20250101997
    Abstract: A pressure cylinder includes a working cylinder and an intensification cylinder that is divided by a separator block. A working piston is arranged in the working cylinder and connected to a working rod that extends to an end portion. An intensification piston and an intensification rod are arranged in the intensification cylinder. A pump is configured to provide a pressurized hydraulic fluid to the pressure cylinder. A fluid reservoir is configured to supply a hydraulic fluid to the pump. A first valve is configured to selectively regulate hydraulic fluid flow between the pressure cylinder and the fluid reservoir and the pump. A second valve is configured to selectively regulate fluid flow between a first valve and the advance intensification chamber. A controller is in communication with the first valve and the second valve. The controller is configured to coordinate movement of the working piston and the intensification piston.
    Type: Application
    Filed: July 10, 2023
    Publication date: March 27, 2025
    Inventor: David Simone
  • Patent number: 12233412
    Abstract: Disclosed are cartridge components, cartridges, systems, and methods for isolating analytes from biological samples. In various aspects, the cartridge components, cartridges, systems, and methods may allow for a rapid procedure that requires a minimal amount of material from complex fluids.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: February 25, 2025
    Assignee: Xzom, Inc.
    Inventors: Robert Turner, James Madsen, Kai Yang, Juan Pablo Hinestrosa Salazar, Rajaram Krishnan, Pedro David Simon Herrera
  • Publication number: 20240383944
    Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.
    Type: Application
    Filed: December 1, 2023
    Publication date: November 21, 2024
    Applicant: Massachusetts Institute of Technology
    Inventors: Mark David Simon, Bradley L. Pentelute, Andrea Adamo, Patrick Louis Heider, Klavs F. Jensen
  • Publication number: 20240368216
    Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.
    Type: Application
    Filed: November 29, 2023
    Publication date: November 7, 2024
    Applicant: Massachusetts Institute of Technology
    Inventors: Mark David Simon, Bradley L. Pentelute, Andrea Adamo, Patrick Louis Heider, Klavs F. Jensen
  • Publication number: 20240342177
    Abstract: Disclosed herein are pharmaceutical compositions for the treatment of cancer. In particular, disclosed herein are methods and uses of the pharmaceutical compositions for treating, preventing and/or managing cancers of the brain and/or central nervous system. The pharmaceutical compositions may comprise: (i) 5-FU, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable analogue thereof; (ii) folinic acid, or a pharmaceutically acceptable salt thereof; and (iii) a cyclodextrin or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 4, 2021
    Publication date: October 17, 2024
    Inventors: Richard David RANSON, Christian Damian TOOULI, David Simon ZIEGLER
  • Publication number: 20240295192
    Abstract: A fuel supply circuit of an aircraft engine includes a centrifugal pump mechanically coupled with an engine shaft delivering mechanical power. The circuit further includes at least one electromagnetic pump including at least one stator delimiting an annular internal volume in which is present a rotor able to drive a fluid, a plurality of magnets annularly distributed on the rotor and at least a plurality of coils annularly distributed inside the stator face-to-face with the magnets. The rotor is connected to the engine shaft by a one-way clutching element.
    Type: Application
    Filed: May 6, 2024
    Publication date: September 5, 2024
    Applicant: SAFRAN HELICOPTER ENGINES
    Inventors: Franck Albert Robert DUPEU, Jean-Marie André Robert GIGON, David Simon Serge TAIEB
  • Publication number: 20240274746
    Abstract: Disclosed herein are methods for the growth of (110) GaAs solar cells by hydride vapor phase epitaxy (HVPE) as an advance towards a (110)-oriented device platform with substrate reuse via spalling. Controlled spalling offers a fracture-based path to substrate amortization, allowing device removal and substrate reuse, but the faceted surface generated in spalling of (100)-GaAs presents hurdles to direct regrowth of subsequent devices. Spalling of (110)-oriented substrates takes advantage of the natural (110) cleavage plane in zinc-blende III-V materials, eliminating this faceting.
    Type: Application
    Filed: June 6, 2022
    Publication date: August 15, 2024
    Inventors: Kevin Louis SCHULTE, Wondwosen Tilahun METAFERIA, Aaron Joseph PTAK, John David SIMON
  • Patent number: 12043646
    Abstract: Methods and systems for control of solid phase peptide synthesis are generally described. Control of solid phase peptide synthesis involves the use of feedback from one or more reactions and/or processes (e.g., reagent removal) taking place in the solid phase peptide synthesis system. In some embodiments, a detector may detect one or more fluids flowing across a detection zone of a solid phase peptide synthesis system and one or more signals may be generated corresponding to the fluid(s). For instance, an electromagnetic radiation detector positioned downstream of a reactor may detect a fluid exiting the reactor after a deprotection reactor and produce a signal(s). In some embodiments, based at least in part on information derived from the signal(s), a parameter of the system may be modulated prior to and/or during one or more subsequent reactions and/or processes taking place in the solid phase peptide synthesis system.
    Type: Grant
    Filed: December 20, 2022
    Date of Patent: July 23, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Dale Arlington Thomas, III, Alexander James Mijalis, Bradley L. Pentelute, Mark David Simon, Surin Mong
  • Publication number: 20240226303
    Abstract: A solidified melt extrudate comprising an active pharmaceutical ingredient in an amorphous form and a combination of at least two polymers.
    Type: Application
    Filed: March 4, 2022
    Publication date: July 11, 2024
    Inventors: Ammar ALMAJAAN, Gavin Paul ANDREWS, David Simon JONES, Mariana Palmeira BEZERRA, Walkiria Santos SCHLINDWEIN, Karina WOJDAT
  • Patent number: 12006873
    Abstract: A fuel supply circuit of an aircraft engine includes a centrifugal pump mechanically coupled with an engine shaft delivering mechanical power. The circuit further includes at least one electromagnetic pump including at least one stator delimiting an annular internal volume in which is present a rotor able to drive a fluid, a plurality of magnets annularly distributed on the rotor and at least a plurality of coils annularly distributed inside the stator face-to-face with the magnets. The rotor is connected to the engine shaft by a one-way clutching element.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: June 11, 2024
    Assignee: SAFRAN HELICOPTER ENGINES
    Inventors: Franck Albert Robert Dupeu, Jean-Marie André Robert Gigon, David Simon Serge Taieb
  • Publication number: 20240187096
    Abstract: Devices, systems and methods for encoding information using optical components are described. An example photonic filtered sampler includes a spectral shaper configured to receive an optical pulse train, a dispersive element positioned to receive an output of the spectral shaper and to expand spectral contents thereof in time, and a modulator configured to receive an output of the dispersive element and a radio frequency (RF) signal, and to produce a modulated output optical signal in accordance with the RF signal. In this configuration, one or more characteristics of the modulated output optical signal is determined based on a spectral shape provided by the spectral shaper and dispersive properties of the dispersive element.
    Type: Application
    Filed: February 12, 2024
    Publication date: June 6, 2024
    Inventors: Brandon Walter Buckley, David Simon Perlmutter, Peter Thomas Setsuda DeVore, Apurva Shantharaj Gowda, Jason Thomas Chou
  • Patent number: 12003272
    Abstract: Methods, devices and systems for providing accurate measurements of timing errors using optical techniques are described. An example timing measurement device includes an optical hybrid that receives two optical pulse trains and produces two or more phase shifted optical outputs. The timing measurement device further includes two or more optical filters that receive the outputs of the optical hybrid to produce multiple pulse signals with distinctive frequency bands. The device also includes one or more photodetectors and analog-to-digital converters to receive to produce electrical signals in the digital domain corresponding to the optical outputs of the hybrid. A timing error associated with the optical pulse trains can be determined using the electrical signals in digital domain based on a computed phase difference between a first frequency band signal and a second frequency band signal and a computed frequency difference between the first frequency band signal and the second frequency band.
    Type: Grant
    Filed: February 9, 2022
    Date of Patent: June 4, 2024
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Peter Thomas Setsuda DeVore, Apurva Shantharaj Gowda, David Simon Perlmutter, Joshua Linne Olson, Jason Thomas Chou
  • Patent number: 11996889
    Abstract: Devices, systems and methods for encoding information using optical components are described. An example photonic filtered sampler includes a spectral shaper configured to receive an optical pulse train, a dispersive element positioned to receive an output of the spectral shaper and to expand spectral contents thereof in time, and a modulator configured to receive an output of the dispersive element and a radio frequency (RF) signal, and to produce a modulated output optical signal in accordance with the RF signal. In this configuration, one or more characteristics of the modulated output optical signal is determined based on a spectral shape provided by the spectral shaper and dispersive properties of the dispersive element.
    Type: Grant
    Filed: January 24, 2023
    Date of Patent: May 28, 2024
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Brandon Walter Buckley, David Simon Perlmutter, Peter Thomas Setsuda DeVore, Apurva Shantharaj Gowda, Jason Thomas Chou
  • Publication number: 20240150328
    Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.
    Type: Application
    Filed: August 23, 2023
    Publication date: May 9, 2024
    Inventors: Qianhe ZHOU, Michael BOCKER, David Simon MILLAN, Ho Man CHAN, Luis SOARES, Matthew NETHERTON, Sabine K. RUPPEL, Zhaoxia YANG, Jason T. LOWE, Francois BRUCELLE