Patents by Inventor Da Jung Ji

Da Jung Ji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Daphne genkwa extracts, and pharmaceutical composition containing fractions of the extracts or compounds separated from the extracts as active ingredients for preventing or treating atopic dermatitis
    Patent number: 9428520
    Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of Daphne genkwa, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: August 30, 2016
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Jae Wha Kim, Kyung Seop Ahn, Ho Bum Kang, Sei Ryang Oh, Jae Jong Go, Joo Heon Kim, Jang Mi Sun, Jae Sung Song, Hyun Woo Oh, Da Jung Ji
  • Pharmaceutical composition for treating wounds or revitalizing skin comprising extracts, fractions thereof or diterpene compounds separated from the fractions as active ingredient
    Patent number: 9061022
    Abstract: The present invention relates to a pharmaceutical composition for treating wounds or revitalizing skin comprising the Euphorbia kansui extract, the fractions thereof, or the diterpene compound isolated therefrom as an active ingredient. The Euphorbia kansui extract may act on epithelial cells to induce PKD1 activity required for improving the reproduction capability of differentiated epithelial cells, and thus may induce the phosphorylation of lower ERK1 and the generation of Cycline D, thus exhibiting an excellent ability to activate the reproduction of damaged skin. Therefore, the Euphorbia kansui extract may be used effectively as an active ingredient in a pharmaceutical composition for treating wounds or reproducing skin, a health food for recovering skin damage or reproducing skin, or a functional cosmetic for inducing skin cell activity.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: June 23, 2015
    Assignee: Korea Research Institute of Bioscience And Biotechnology
    Inventors: Jae Wha Kim, Sei Ryang Oh, Kyung Seop Ahn, Ho Bum Kang, Ok-Kyoung Kwon, Seung Ho Kim, Jang Mi Son, Hyuk Hwan Song, Hee Gu Lee, Byeong Hwa Jeon, Da Jung Ji, Khiev Piseth
  • PHARMACEUTICAL COMPOSITION FOR TREATING WOUNDS OR REVITALIZING SKIN COMPRISING EUPHORBIA KANSUI EXTRACTS, FRACTIONS THEREOF OR DITERPENE COMPOUNDS SEPARATED FROM THE FRACTIONS AS ACTIVE INGREDIENT
    Publication number: 20150093456
    Abstract: The present invention relates to a pharmaceutical composition for treating wounds or revitalizing skin comprising the Euphorbia kansui extract, the fractions thereof, or the diterpene compound isolated therefrom as an active ingredient. The Euphorbia kansui extract may act on epithelial cells to induce PKD1 activity required for improving the reproduction capability of differentiated epithelial cells, and thus may induce the phosphorylation of lower ERK1 and the generation of Cycline D, thus exhibiting an excellent ability to activate the reproduction of damaged skin. Therefore, the Euphorbia kansui extract may be used effectively as an active ingredient in a pharmaceutical composition for treating wounds or reproducing skin, a health food for recovering skin damage or reproducing skin, or a functional cosmetic for inducing skin cell activity.
    Type: Application
    Filed: December 3, 2014
    Publication date: April 2, 2015
    Inventors: Jae Wha KIM, Sei Ryang Oh, Kyung Seop AHN, Ho Bum KANG, Ok-Kyoung KWON, Seung Ho KIM, Jang Mi SON, Hyuk Hwan SONG, Hee Gu LEE, Byeong Hwa Jeon, Da Jung Ji, Khiev Piseth
  • DAPHNE GENKWA EXTRACTS, AND PHARMACEUTICAL COMPOSITION CONTAINING FRACTIONS OF THE EXTRACTS OR COMPOUNDS SEPARATED FROM THE EXTRACTS AS ACTIVE INGREDIENTS FOR PREVENTING OR TREATING ATOPIC DERMATITIS
    Publication number: 20140072664
    Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of Daphne genkwa, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.
    Type: Application
    Filed: May 17, 2012
    Publication date: March 13, 2014
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Jae Wha Kim, Kyung Seop Ahn, Ho Bum Kang, Sei Ryang Oh, Jae Jong Go, Joo Heon Kim, Jang Mi Sun, Jae Sung Song, Hyun Woo Oh, Da Jung Ji