Patents by Inventor Dabing Ye

Dabing Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRIDOPYRIMIDINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF
    Publication number: 20240166645
    Abstract: A pyridopyrimidinone derivative as represented by formula I, and a tautomer, a stereoisomer, a hydrate, a solvate, a pharmaceutically acceptable salt thereof or a prodrug thereof. The pyridopyrimidinone derivative has a good SOS1 inhibitory effect.
    Type: Application
    Filed: February 8, 2022
    Publication date: May 23, 2024
    Applicant: Wuhan Humanwell Innovative Drug Research and Development Center Limited Company
    Inventors: Xuejun ZHANG, Shaohua CHANG, Xueqiang LI, Dabing YE, Hongqiang WANG, Hongna SUN, Jun YANG, Li'e LI
  • CD73 INHIBITOR AND USE THEREOF
    Publication number: 20230399314
    Abstract: The present disclosure provides a novel compound for effectively inhibiting the activity of CD73, a preparation method thereof, and use thereof in the preparation of drugs, and the novel compound is a compound represented by formula I, or a tautomer, stereoisomer, hydrate, solvate, pharmaceutically acceptable salt, or prodrug thereof.
    Type: Application
    Filed: November 5, 2021
    Publication date: December 14, 2023
    Applicant: WUHAN HUMANWELL INNOVATIVE DRUG RESEARCH AND DEVELOPMENT CENTER LIMITED COMPANY
    Inventors: Xuejun ZHANG, Shaohua CHANG, Dabing YE, Sijun LEI, Yonggang WANG, Yong LIU, Hongna SUN, Jun YANG, Lie LI
  • PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF
    Publication number: 20220064172
    Abstract: Provided is a new compound capable of effectively inhibiting ATX. The compound is represented by formula I, or the compound is a tautomer, a stereoisomer, a hydrate, a solvate, a salt, or a prodrug of the compound represented by formula I. In formula (I), R1 and R2 are independently selected from —H or —CH3, provided that: R1 and R2 are not —H at the same time or are not —CH3 at the same time.
    Type: Application
    Filed: January 22, 2020
    Publication date: March 3, 2022
    Inventors: Xuejun ZHANG, Dabing YE, Lie LI, Jie SHEN, Xiaohua DING, Hongna SUN, Zhe LIU, Yang ZANG, Yonggang WEI
  • Method for preparing efficiently synthetic sitafloxacin intermediate (7S)-5-azaspiro[2.4]heptane-7-yl tert-butyl carbamate
    Patent number: 10358417
    Abstract: The present invention discloses a preparation method for efficient synthesis of sitafloxacin intermediate (7S)-5-azaspiro[2.4]heptane-7-yl-tert-butyl carbamate, comprising the following steps: reacting to obtain reacting to obtain reacting to obtain and reacting to obtain In the present invention, a single compound with a relatively high ee value can be obtained, the unnecessary waste of materials is avoided, the yield is significantly improved, the operation is simple, the industrial scale-up is easy, and the production cost is reduced.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: July 23, 2019
    Assignee: Chen-Stone (Guangzhou) Co., Ltd.
    Inventors: Yingjie Lai, Dabing Ye, Fengrui Lang, Xiangtian Long
  • METHOD FOR PREPARING EFFICIENTLY SYNTHETIC SITAFLOXACIN INTERMEDIATE (7S)-5-AZASPIRO[2.4]HEPTANE-7-YL TERT-BUTYL CARBAMATE
    Publication number: 20180370914
    Abstract: The present invention discloses a preparation method for efficient synthesis of sitafloxacin intermediate (7S)-5-azaspiro[2.4]heptane-7-yl-tert-butyl carbamate, comprising the following steps: reacting to obtain reacting to obtain reacting to obtain and reacting to obtain In the present invention, a single compound with a relatively high ee value can be obtained, the unnecessary waste of materials is avoided, the yield is significantly improved, the operation is simple, the industrial scale-up is easy, and the production cost is reduced.
    Type: Application
    Filed: April 25, 2017
    Publication date: December 27, 2018
    Inventors: Yingjie Lai, Dabing Ye, Fengrui Lang, Xiangtian Long