Abstract: Provided is a new compound capable of effectively inhibiting ATX. The compound is represented by formula I, or the compound is a tautomer, a stereoisomer, a hydrate, a solvate, a salt, or a prodrug of the compound represented by formula I. In formula (I), R1 and R2 are independently selected from —H or —CH3, provided that: R1 and R2 are not —H at the same time or are not —CH3 at the same time.

Abstract: Provided are a 15-PGDH inhibitor and the use thereof. The 15-PGDH inhibitor is a heterocyclic compound as represented by formula I, a solvate thereof, a pharmaceutically acceptable salt thereof, a solvate of a pharmaceutically acceptable salt thereof, or a prodrug thereof. The compound has a good inhibitory effect on 15-PGDH.

Abstract: A modular combined socket, which comprises a circuit module, a connection module and at least two socket modules. The circuit module includes a connection module interface and a socket interface with at least four conductive paths connected to each other. The connection module includes a power supply interface and a circuit module interface with at least four conductive paths that are connected to each other and can be connected to the connection module interface of the circuit module through the circuit module interface, and the socket module includes two or three interconnected socket modules. The output socket and line interface of the conductive path, each of the socket modules can be connected to different conductive paths of the socket interface through the line interface. It has the advantages of flexible combination, large load bearing and strong anti-interference. The present invention also provides a modular power supply assembly.

Abstract: The invention discloses a method for improving rice yield and a protein used thereof. The invention provides a method for cultivating the target rice, comprising the following steps of inhibiting the activity of RAY1 protein in original rice to obtain target rice; compared with the original rice, the target rice shows higher yield and/or larger grain size and/or stronger resistance to rice blast and/or higher plant height and/or longer stem internode length; the RAY1 protein is a protein composed of an amino acid sequence shown as SEQ ID No. 1 in a sequence list. The invention uses CRISPR/Cas9 technology to realize site-directed editing rice RAY1 gene, through knocking out rice RAY1 gene by frameshift mutation, the protein RAY1 is inactivated, and a new generation of rice germplasm with significantly improved yield is obtained.

Abstract: The present invention discloses a method for preparing a rice photosensitive male sterile material and related genes thereof. The method for preparing photosensitive male sterile rice of the present invention includes: reducing the abundance of protein RMS1 in the target rice, reducing the activity of the protein RMS1 in the target rice or reducing the content of the protein RMS1 in the target rice to obtain the photosensitive male sterile rice. The protein RMS1 is the following A1) or A2): A1), the amino acid sequence of which is as shown in SEQ ID No. 1 in the sequence listing; A2), a homologous protein having more than 98% identity with A1) and is derived from rice. The present invention obtains a rice photosensitive male sterile material by controlling the RMS1 gene of rice and its encoded protein, and achieves the fertility of rice under different light conditions.

Abstract: A smart desk and chair includes a desk having at least one lift arm that is expandable and retractable for adjusting the height of a desk surface and a chair having a sensor included inside a chair seat where the sensor detects the presence or absence of a user seated in the chair. A controller in the desk controls the position of the at least one lift arm in the desk. The desk and chair are connected wirelessly enabling the desk surface to be automatically raised or lowered in relation to the floor depending on the standing or seated position of the user.

Abstract: The invention discloses a method for improving rice yield and a protein used thereof. The invention provides a method for cultivating the target rice, comprising the following steps of inhibiting the activity of RAY1 protein in original rice to obtain target rice; compared with the original rice, the target rice shows higher yield and/or larger grain size and/or stronger resistance to rice blast and/or higher plant height and/or longer stem internode length; the RAY1 protein is a protein composed of an amino acid sequence shown as SEQ ID No. 1 in a sequence list. The invention uses CRISPR/Cas9 technology to realize site-directed editing rice RAY1 gene, through knocking out rice RAY1 gene by frameshift mutation, the protein RAY1 is inactivated, and a new generation of rice germplasm with significantly improved yield is obtained.

Abstract: A modular combined socket, which comprises a circuit module, a connection module and at least two socket modules. The circuit module includes a connection module interface and a socket interface with at least four conductive paths connected to each other. The connection module includes a power supply interface and a circuit module interface with at least four conductive paths that are connected to each other and can be connected to the connection module interface of the circuit module through the circuit module interface, and the socket module includes two or three interconnected socket modules. The output socket and line interface of the conductive path, each of the socket modules can be connected to different conductive paths of the socket interface through the line interface. It has the advantages of flexible combination, large load bearing and strong anti-interference. The present invention also provides a modular power supply assembly.

Abstract: A high-throughput and rapid nucleic acids detection method based on capillary microarrays comprises the steps that firstly, microarray containing a number of hydrophilic and vertical micro-channels is fabricated by capillary assembling, casting and machining, and the outer surface of the capillary array is coated with super-hydrophobic Ultra-Ever Dry paint; secondly, different primer sets are individually loaded into the micro-channels and air-dried to adhere them on the inner surface, and then the microarray is anchored into a reaction tube; thirdly, the reaction mixture is introduced into every microchannel at once through capillary force by a special designed sample-loading adaptor, and then the amplification reaction is performed in the temperature control device; and finally, the fluorescence can either be measured continually during the reaction for real-time detection or be recorded once in the end for endpoint detection. Moreover, the products can also be recovered for other use later.

Abstract: A smart desk and chair includes a desk having at least one lift arm that is expandable and retractable for adjusting the height of a desk surface and a chair having a sensor included inside a chair seat where the sensor detects the presence or absence of a user seated in the chair. A controller in the desk controls the position of the at least one lift arm in the desk. The desk and chair are connected wirelessly enabling the desk surface to be automatically raised or lowered in relation to the floor depending on the standing or seated position of the user.

Abstract: The present invention discloses a high-throughput and rapid nucleic acids detection method based on capillary microarrays, and belongs to the technical field of biomedicine.

Abstract: Provided is a breeding method for two lines hybrid rice based on the rice mutant osms4 (Oryza sativa male sterile 4), which was originally selected from the mutagenizing seeds of japonica cultivar 9522 with 60Co gamma ray, and the stable inheritance osms4 mutant was obtained after three generations backcrossing, which is regulated by a recessive single gene OsMS4. The invention is related to the usage of OsMS4 gene (also known as Carbon Starved Anther, the CSA gene), osms4 mutant can be used as male sterile line under short day condition in both japonica and indica background, which grows abnormal anther with defection during second mitosis stage and produces completely sterile pollen. While under the long day condition, the osms4 mutant can be used as maintainer liner and produces normal pollen.