Patents by Inventor Dadong Chen

Dadong Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotide molecules encoding proteins having proteinase inhibitor activity
    Patent number: 6689582
    Abstract: BTL.010 is a novel human serine proteinase inhibitor of the Kunitz family that exhibits greater potency towards neutral serine proteinases, particularly leukocyte elastase and proteinase 3 than towards trypsin-like proteinases. BTL.010, or variants thereof, may be employed as therapeutics in diseases such as emphysema, idiopathic pulmonary fibrosis, adult respiratory distress syndrome, cystic fibrosis, rheumatoid arthritis, organ failure, and glomerulonephritis in which uncontrolled proteolysis due to neutral serine proteinase activity results in tissue damage.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: February 10, 2004
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Christopher Davies, Dadong Chen, Steve Roczniak
  • Methods for modulating angiogenesis
    Publication number: 20030045489
    Abstract: The present invention provides methods for modulating angiogenesis by administering anti-angiogenic FGF-19 polypeptides to a subject. Methods of modulating angiogenesis by administering an anti-angiogenic FGF-19 nucleic acid are also provided.
    Type: Application
    Filed: November 21, 2001
    Publication date: March 6, 2003
    Inventors: John E. Murphy, Jianmin Chen, Nathalle Dubois-Stringfellow, Dadong Chen
  • Protein having proteinase inhibitor activity
    Patent number: 6180607
    Abstract: BTL.010 is a novel human serine proteinase inhibitor of the Kunitz family that exhibits greater potency towards neutral serine proteinases, particularly leukocyte elastase-, and proteinase 3, than towards trypsin-like proteinases. BTL.010, or variants thereof, may be employed as therapeutics in diseases such as emphysema, idiopathic pulmonary fibrosis, adult respiratory distress syndrome, cystic fibrosis, rheumatoid arthritis, organ failure, and glomerulonephritis in which uncontrolled proteolysis due to neutral serine proteinase activity results in tissue damage.
    Type: Grant
    Filed: August 5, 1999
    Date of Patent: January 30, 2001
    Inventors: Christopher Davies, Dadong Chen, Steve Roczniak